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Gene Regulation and Mutation

Total questions: 20

Worksheet time: 31mins

Name
Class
Date
1.

Mutations increase the likelihood that a species will survive in a changing environment because they are a source of variation in the species.

a)

True

b)

False

2.

The type of mutation represented by these sequences is:

Normal: TAGCCAGTA

Diseased: TAACCAGTA

a)

Insertion

b)

Deletion

c)

Substitution

d)

Frameshift

3.
Any change in the sequence of DNA is...
a)
transgenic shift
b)
Single Genotype
c)
Monohybrid Trait
d)
Mutation
4.

DNA molecule segment is : TTA-CGC-AAG

The mutated DNA segment is TTC-GCA-AG. This is an example of ___ mutation.

a)

Substitution

b)

Deletion

c)

Insertion

d)

Inversion

5.

Why are insertion and deletion mutations so harmful?

a)

They change all of the codons from the mutation on down the line, which changes the amino acid sequence

b)

They insert things that an organism doesn't need.

c)

They often delete things that organisms need.

d)

Insertion and deletions are not any more harmful than substitution mutations.

6.

One nucleotide base is changed so only one amino acid

is affected

a)

Substitution Mutation

b)

Point Mutation

c)

Translocation

d)

Inverse Mutation

7.

A point mutation where one nucleotide base replaces an original nucleotide base

a)

Inversion Mutation

b)

Chromosomal Mutation

c)

Translocation

d)

Substitution Mutation

8.

A substitution mutation that has no effect

on amino acids sequence

a)

Insertion Mutation

b)

Translocation

c)

Silent Mutation

d)

Deletion Mutation

9.

A nucleotide base is inserted or deleted shifting the entire DNA sequence. Entire protein will be changed.

a)

Substitution Mutation

b)

Silent Mutation

c)

Frameshift Mutation

d)

Translocation

10.

A frameshift mutation where a nucleotide base

is removed from the DNA sequence.

a)

Deletion Mutation

b)

Substitution Mutation

c)

Translocation

d)

Silent Mutation

11.

A frameshift mutation where a nucleotide base is added

to the DNA sequence

a)

Insertion Mutation

b)

Deletion Mutation

c)

Substitution Mutation

d)

Chromosomal Mutation

12.

What mutation has occurred here?

T-G-A-C-C-A

T-G-A-G-C-A

a)

Substitution

b)

Deletion

c)

Insertion

d)

Frameshift

13.

Which mutation will cause translation to stop?

a)

Mutations 1 and 3 only

b)

Mutation 1 only

c)

Mutation 2 only

d)

Muations 1, 2, 3

14.
Which RNA bases would pair with TACGAA in transcription? 
a)
AUGCUU
b)
ATGCTT
c)
GCATCC
d)
GCAUCC
15.
A type of substitution in which no  amino acids change is called 
a)
Missense
b)
Nonsense
c)
Silent
d)
Deletion
16.
Which of the following can increase the rate of mutation?
a)
UV Radiation
b)
Viruses
c)
toxic chemicals 
d)
All of the above
17.
Original: ATC CAT
Mutation: ATC GCAT
What mutation occurred?
a)
deletion
b)
insertion
c)
silent
d)
transverse
18.
If you are missing or have an extra base  at the end of your mutated DNA . What type of mutation occurred?
a)
Substitution
b)
Frameshift
c)
Duplication 
d)
Insertion
19.
Normal-
GAG-CTC-GAC-AGA
Mutant
GAG CTC-CAC-AGA
a)
no mutation
b)
substitution
c)
insertion
d)
deletion
20.
How can a person's muscle cells have the same exact DNA sequences as their nerve cells even though the look and perform completely different?
a)
The two different cells become mutated
b)
The proteins expressed in each cell are different
c)
They actually have different DNA in the two types of cells.
d)
The genome of the different cells changes