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Human Inheritance

Total questions: 118

Worksheet time: 2hrs 21mins

Name
Class
Date
1.

The chromosomes inside you exist as ________, one from each of your parents.

a)

Duplicates

b)

Genes

c)

Pairs

d)

Alleles

2.

Human ABO blood type is an example of a trait that is determined by ___________ alleles.

a)

One

b)

Single

c)

Multpile

d)

No

3.

A _________ shows phenotypes of genetically related family members.

a)

Pedigree

b)

Punnett Square

c)

Codominance

d)

Genetic Chart

4.

_______ occurs when more than one gene affects a trait

a)

Incomplete dominance

b)

Codominance

c)

Multiple alleles

d)

Polygenic inheritance

5.

_______ mean that three or more possible alleles determine the trait

a)

Incomplete dominance

b)

Codominance

c)

Multiple alleles

d)

Polygenic inheritance

6.
Can an individual be a carrier for a dominant  genetic disorder. 
a)
Yes 
b)
No
7.

Pick the disorder that is a recessive genetic disorder.

a)

Huntington's Disease

b)

Cystic Fibrosis

c)

Achondroplasia

d)

They are all recessive genetic disorders.

8.
What is a carrier? 
a)
An individual is heterozygous for a dominant recessive genetic disorder.
b)
An individual is homozygous for a recessive genetic disorder. 
c)
An individual is heterozygous for a recessive genetic disorder. 
d)
An individual is homozygous for a dominant genetic disorder. 
9.
Can an individual be a carrier for a dominant  genetic disorder. 
a)
Yes 
b)
No
10.

Can two parents with albinism have an unaffected child?

a)

Yes

b)

No

11.
In the second generation-how many people have the disease or display the physical trait?
a)
2
b)
4
c)
5
d)
6
12.

What is the mode of inheritance shown here?

a)

Dominant genetic disorder

b)

Recessive genetic disorder

13.
The genotype of the affected son and daughter at the bottom of this pedigree...
a)
homozygous dominant
b)
homozygous recessive
c)
heterozygous
d)
Can't tell
14.

If this pedigree shows a recessive genetic disorder, what MUST the genotype of individual II-3 be?

a)

HH

b)

Hh

c)

hh

d)

None of the above

15.
How many carrier males are present? 
a)
2
b)
4
c)
6
d)
8
16.
In a pedigree, what shape represents a male?
a)
circle
b)
square
c)
triangle
d)
diamond
17.

How many people in this whole pedigree are heterozygous?

a)

7

b)

3

c)

4

d)

6

e)

5

18.
True or False.  Some genetic disorders are caused by changes in the DNA of genes, but some are caused by changes in the structure or number of chromosomes.
a)
True
b)
False
19.
True or False.  Pictured above is a karyotype of a male human being.
a)
True
b)
False
20.
True or False.  With the genetic disorder known as Down Syndrome, a person's cells have an extra copy of chromosome 21. 
a)
True
b)
False
21.
True or False.  A clone has exactly the same genes as the organism from which it was produced.
a)
True
b)
False
22.
True or False.  Genetic engineering is used to produce a protein called insulin, which helps people who suffer from diabetes.
a)
True
b)
False
23.
True or False.  The mission Human Genome Project is to identify the DNA code of every gene in each of our chromosomes.
a)
True
b)
False
24.

Trisomy 18 is classified as a

a)

single allele dominant trait

b)

single allele recessive trait

c)

disorder caused by nondisjunction

25.

Having an extra #21 chromosome is (check all that apply)

a)

Down Syndrome

b)

caused by nondisjunction

c)

Klinefelter Syndrome

26.
What disease is characterized by abnormally shaped red blood cells?
a)
hemophilia
b)
sickle cell anemia
c)
phenylketonuria
d)
Huntington's 
27.
This karyotype is taken from a  ________.
a)
female with Turner's syndrome
b)
male with Down's syndrome
c)
female with Down's syndrome
d)
normal female
28.

Which of the following is a genetic disorder that results when two mutated alleles are inherited?

a)

Down syndrome

b)

colorblindness

c)

cystic fibrosis

d)

hemophilia

29.

Which of the following is the protein that is NOT normal in people with sickle-cell disease?

a)

mucus

b)

clotting protein

c)

karyotype

d)

hemoglobin

30.

A couple that have a family history of a genetic disorder might wish to receive advice from a genetic counselor

a)

True

b)

False

31.

________ is a genetic disorder caused by a recessive allele on the X chromosome

a)

Syndromw down

b)

colorblindness

c)

cystic fibrosis

d)

hemophilia

32.

A condition in which a person's skin, hair, and eyes lack normal coloring is called ___________

a)

albinism

b)

Syndrome down

c)

colorblindness

d)

hemophilia

33.
Cystic Fibrosis is a genetic disorder in which the body produces thick mucus in the lungs and intestines,
a)
True
b)
False
34.
Disease that causes red blood cells to be shaped incorrectly.
a)
Hemophilia
b)
Sickle Cell Disease
c)
Anemia
35.
If a person carries a gene for a specific disorder they will always develop the disease.
a)
True
b)
False
36.
Albinism is a recessive genetic disorder.  An individual who has two recessive alleles will be albino; while an individual with one dominant allele will not. What is the definition of a recessive genetic disorder? 
a)
One copy of an abnormal gene must be present for the disease or trait to develop. 
b)
 Two copies of an abnormal gene must be present in order for the disease or trait to develop?
37.
If a recessive genetic disorder mean that you need 2 abnormal alleles to express the disorder.  What dose a dominant genetic disorder mean?
a)
An individual only needs 1 abnormal allele to express the disorder. 
b)
An individual needs 2 abnormal alleles to express the disorder. 
c)
An individual will never express the disorder.
d)
An individual needs 3 abnormal alleles to express the disorder. 
38.

You either have a widow's peak or you don't. This is an example of

a)

a single gene with 2 traits

b)

a gene with multiple traits

c)

a trait controlled by many genes

39.

Which is NOT a pattern of inheritance in humans?

a)

single gene with 1 allele

b)

single gene with2 alleles

c)

single gene with multiple alleles

d)

trait controlled by many genes

40.

There are hundreds of shades of skin color. This is an example of

a)

a single gene with 2 traits

b)

single gene with multiple traits

c)

trait controlled by many genes

41.

In humans, the sex chromosomes are the ____________ pair of chromosomes.

a)

1st

b)

15th

c)

23rd

d)

46th

42.

If a recessive trait is found on the X chromosome who is more likely to have that trait?

a)

males

b)

females

43.

Would Lebron James be the same basketball player he is regardless of where he was born and raised?

a)

Yes, his skills are entirely genetic

b)

No, he might not be as tall and fit if he had grown up with less access to food.

44.

A picture of a set of chromosomes is a

a)

genetic disorder

b)

karyotype

c)

pedigree

45.

A genetic disorder caused by an extra 21st chromosome

a)

cystic fibrosis

b)

sickle cell anemia

c)

hemophilia

d)

Down syndrome

46.

A genetic disorder that can cause pain and blood clots due to red blood cells becoming misshapen.

a)

cystic fibrosis

b)

sickle cell anemia

c)

hemophilia

d)

Down syndrome

47.

A sex linked genetic disorder that causes blood to clot slowly or not at all.

a)

cystic fibrosis

b)

sickle cell anemia

c)

hemophilia

d)

Down syndrome

48.

A genetic disorder that causes abnormally thick mucus in the lungs and intestines.

a)

cystic fibrosis

b)

sickle cell anemia

c)

hemophilia

d)

Down syndrome

49.

What is a strong clue that a trait you are looking at on a pedigree is a sex linked trait?

a)

there are no female carriers, they either have the trait or they don't

b)

there are no male carriers, they either have the trait or they don't

50.

A gene that is found on the X or Y chromosome is called a(n)

a)

codominant gene

b)

autosomal gene

c)

somatic gene

d)

sex-linked gene

51.

True or False: Males always inherit their X chromosome from their mother

a)

True

b)

False

52.

If a woman is a carrier for an X-linked recessive trait of hemophilia and her husband has hemophilia, which of the following is true?

a)

All sons will have hemophilia but daughters would not have hemophilia

b)

all daughters will have hemophilia

c)

50% of daughters and 50% of sons could have hemophilia

d)

100% of sons could have hemophilia and 100% of daughters could be carriers

53.

Eye color in fruit flies is sex-linked. If a female fruit fly heterozygous for red eyes (XRXr) mates with a white-eyed male (XrY), what percent of their offspring would have white eyes?

a)

0%

b)

25%

c)

50%

d)

75%

54.

What are some symptoms of CF?

a)

Salty-Tasting Sweat

b)

Cold Feet

c)

Yellow Eyes

d)

Digestive System Problems

e)

Chest Problems

55.

what does CF stand for?

a)

Chick-fil-A

b)

Cystic Fibrosis

c)

Crummy Feet

56.

What chromosome is affected by CF?

a)

10

b)

7

c)

8

d)

what is a chromosome???????

57.

If you see crescent moon shaped red blood cells, what disease does this indicate?

a)

sickle cell disease

b)

cancer

c)

tay sachs

d)

ALS

58.

Symptoms of sickle cell anemia include

a)

fever

b)

joint pain

c)

fatigue

d)

all the above

59.

Sickle cell anemia is caused by

a)

a gene mutation

b)

mosquitoes

c)

bad water

d)

climate change

60.

Sickled shaped red blood cells can make it easier for blood to get stuck in the veins and arteries, causing

a)

stroke

b)

joint pain

c)

heart attack

d)

all the above

61.
Sickle red blood cells have a decreased ability to carry 
a)
nutrients
b)
wastes
c)
oxygen
d)
proteins
62.

Sickled RBC

a)

A

b)

B

63.

Can Down Syndrome be prevented or cured?

a)

Yes

b)

No

64.

Why does Down Syndrome happen?

a)

2 chromosomes

b)

Extra chromosome

c)

A missing chromosome

d)

No chromosomes

65.

Down Syndrome was named after a British doctor, John Langdon Down.

a)

True

b)

False

66.

How can I help someone with Down Syndrome?

a)

Smiling

b)

Inviting them to play with me or have a conversation.

c)

Informing an adult if I see someone being mean to them.

d)

All of the above

67.

People with Down Syndrome will have certain physical features and may have medical problems

a)

True

b)

False

68.

How many chromosomes a baby with born down syndrome will have?

a)

44

b)

46

c)

45

d)

47

69.

Down Syndrome is also called ..

a)

Trisomy 20

b)

Trisomy 22

c)

Trisomy 23

d)

Trisomy 21

70.

Some common physical features of down syndrome

a)

short neck

b)

small ears

c)

small hands

d)

strong muscle tone

71.

What is Hemophilia?

a)

a medical condition in which the ability of the blood to clot is severely reduced, causing the sufferer to bleed severely from even a slight injury.

b)

a genetic disorder where there is a 23rd chromosome

c)

a type of gene

d)

an allele

72.

What is replacemet therapy?

a)

Where a doctor takes all the blood out of someone with hemophilia and replaces it with normal blood

b)

Clotting factors are replaced by injecting (infusing) a clotting factor concentrate into a vein.

c)

taking out the section of the brain with hemophilia

73.
What percentage of the female offspring will be a carrier for this recessive disease?
a)
0%
b)
50%
c)
100%
d)
25%
74.
Hemophilia is a recessive x-linked disorder.
Which genotype represents a female who is a carrier for hemophilia?
a)
XHXh
b)
XhXh
c)
XHXH
d)
XhY
75.
Hemophilia is a recessive x-linked disorder.
Which genotype represents a male with hemophilia?
a)
XHXh
b)
XhXh
c)
XHY
d)
XhY
76.
Which of the following genotypes belongs in the red box in the Punnett square?
a)
XBXb
b)
XbXb
c)
XbY
d)
XBY
77.

This pedigree shows the disease of cystic fibrosis, a dissease where mucus devleops in the lungs. Based on the pedigree, is this condition dominant or recessive?

a)

Dominant

b)

Recessive

78.

How many daughters did I1 and I2 have?

a)

1

b)

2

c)

3

d)

4

79.

This NEW pedigree shows the condition of albinism, which is a deficiency of pigmentation in the hair and skin. Based on the pedigree, is albinism dominant or recessive?

a)

Dominant

b)

Recessive

80.

How are II-5 and II-7 related?

a)

cousins

b)

married

c)

siblings

d)

uncle/nephew

81.
True or False.  Some genetic disorders are caused by changes in the DNA of genes, but some are caused by changes in the structure or number of chromosomes.
a)
True
b)
False
82.
True or False.  Pictured above is a karyotype of a male human being.
a)
True
b)
False
83.
True or False.  A clone has exactly the same genes as the organism from which it was produced.
a)
True
b)
False
84.
True or False.  Genetic engineering is used to produce a protein called insulin, which helps people who suffer from diabetes.
a)
True
b)
False
85.
True or False.  The mission Human Genome Project is to identify the DNA code of every gene in each of our chromosomes.
a)
True
b)
False
86.

Selective breeding is the process of selecting organisms with desired traits to be the parents of the next generation.

a)

True

b)

False

87.

The process of transferring genes from one organism to another

a)

genetic engineering

b)

selective breeding

c)

natural selection

88.

Organisms that contain foreign DNA are called

a)

Genetically Modified Organisms

b)

Genetically Changed Organisms

c)

Genetically Manipulated organisms

89.

Scientists have taken the ________________ gene and inserted it into bacteria to help produce it for individuals with diabetes.

a)

insulin

b)

pepsin

c)

adrenalin

90.
Concerns about genetically modified organisms include(s)
a)
risk to human health
b)
may be harmful to ecosystems
c)
seed/pollen drift to organic farms
d)
all of these are valid concerns
91.

What term is used to express creating an identical copy of a gene or organism?

a)

Hybridization

b)

Inbreeding

c)

Genetic engineering

d)

Cloning

92.

Which kitten is most likely the offspring of this cat?

a)

1

b)

2

c)

3

d)

4

93.

The two examples of selective breeding are:

a)

inbreeding and outbreeding

b)

outbreeding and developing

c)

hybridization and outbreeding

d)

hybridization and inbreeding

94.

A cross of two genetically different individuals

a)

hybridization

b)

inbreeding

c)

outbreeding

95.

Crossing two individuals that have similar desirable characteristics

a)

hybridization

b)

inbreeding

c)

outbreeding

96.

Genetic engineering is also known as

a)

gene therapy

b)

DNA manipulation

c)

artificial selection

97.
The insertion of working copies of a gene into the cells of a person with a genetic disorder in attempt to correct the disorder.
a)
Gene Therapy
b)
Genetic Engineering
c)
Hybridization
d)
Clone
98.

Golden retriever puppies are an example of

a)

inbreeding

b)

hybridization

99.

Labrodoodles are examples of

a)

inbreeding

b)

hybridization

100.

All dogs, no matter what breed, are the same species.

a)

true

b)

false

101.

Selective breeding is a relatively new practice that humans have used.

a)

true

b)

false

102.

Selective breeding probably began as far back as

a)

100 years ago

b)

1000 years ago

c)

10,000 years ago

103.

How many "mothers" were used to clone Dolly?

a)

1

b)

2

c)

3

d)

4

104.

Cloning could be used to repopulate extinct species.

a)

True

b)

False

105.

Check all the reasons a farmer might create GMO's

a)

Save Money

b)

Increase shelf-life of produce

c)

Make plants resistant to pesticides

d)

Produce bad crops

e)

Poison people

106.

What are some products that have been produced using genetic engineering?

a)

Tylenol

b)

insulin

c)

growth hormone

d)

cough syrup

e)

blood clotting factors

107.

In which ways can genetic engineering can improve crops

a)

Make them pest or drought resistant

b)

Make them more nutritious

c)

Make them larger

d)

All answers are correct

108.
Corn and rice are two of these most genetically modified crops in the US.
a)
true
b)
false
109.
Which term refers to a farmer choosing the best corn from this year to plant next year?
a)
natural selection
b)
selective breeding
c)
genetic engineering
d)
genetic transformation
110.
Someone has a wild cat breed with a house cat in order to have a cat that looks wild but is more gentle. This is__.
a)
Genetic Modification
b)
Gene Therapy
c)
Animal Husbandry
d)
Selective breeding
111.
Parkinson's is a disease that could be potentially cured through_____. 
a)
Gene Therapy
b)
Gene Modification
c)
Selective Breeding
d)
Animal Husbandry
112.

a)

A

b)

B

c)

C

d)

D

113.

a)

A

b)

B

c)

C

d)

D

114.

a)

A

b)

B

c)

C

d)

D

115.

a)

A

b)

B

c)

C

d)

D

116.

a)

A

b)

B

c)

C

d)

D

117.

a)

A

b)

B

c)

C

d)

D

118.

a)

A

b)

B

c)

C

d)

D

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