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MSSK Bone Pathology Quiz

Total questions: 10

Worksheet time: 5mins

Name
Class
Date
1.

A 7-year-old complained of pain of his right leg for 3 weeks. He had a fall about a month ago. X-ray shows a radiolucency of his right tibia with a sclerotic edge. What is the most likely diagnosis?

a)

Brodies abscess

b)

Chondroma

c)

Osteosarcoma

d)

Tuberculous osteomyelitis

2.

What bone tumour is associated with lifting of periosteum off bone producing the Codman triangle and a sunburst appearance on X-ray?

a)

Chondroma

b)

Ewing Sarcoma

c)

Osteoma

d)

Osteosarcoma

3.

Which type of skeletal tumour is a small-cell malignant tumour of long bones, rubs, pelvis, scapula and seen in boys under 15?

a)

Chondroma

b)

Ewing Sarcoma

c)

Osteosarcoma

d)

Osteoclastoma

4.

A 78-year-old woman sustained hip fracture when she fell from her bed, which is only 1 foot high. What condition is she most likely suffering from?

a)

Idiopathic osteoporosis

b)

Osteogenesis imperfecta

c)

Type 1 osteoporosis

d)

Type 2 osteoporosis

5.

This bone tumour is caused by heterozygous mutations in IDH1 and IDH2 genes identified in the chondrocytes

a)

Enchondroma

b)

Osteosarcoma

c)

Osteoclastoma

d)

Osteochondroma

6.

This tumour is characterized by multinucleated giant cells in a background of epitheliod to spindle shaped mononuclear cells

a)

Ewing Sarcoma

b)

Osteosarcoma

c)

Osteoclastoma

d)

Chondrosarcoma

7.

This tumour is characterized by islands of hyaline cartilage and myxoid tissue and bizarre chondrocytes in clear spaces

a)

Chondroma

b)

Chondrosarcoma

c)

Osteosarcoma

d)

Osteoclastoma

8.

Which of the statements describe the sequestrum in chronic osteomyelitis

a)

Collection of epitheliod cells surrounded by mononuclear cells

b)

Interconnecting trabeculae of woven bone set within oedematous stroma

c)

Sclerotic, necrotic bone surrounded by inflammatory exudates

d)

Reactive new bone formation in response to inflammation

9.

Spinal TB is a presentation of extra-pulmonary TB. Magnetic resonance showed destruction of vertebrae involving T10-T12. Biopsy was taken from lesion. What would the most likely finding of the biopsy?

a)

Caseous necrosis surrounded by multinucleated giant cells, epitheliod cells and lymphocytes

b)

Granuloma with multinucleated giant cells engulfing birefringent materials

c)

Pieces of necrotic bone surrounded by polymorphonuclear cells

d)

Purulent material with bacterial colony surrounded by neutrophils and fibroblast

10.

A 20-year-old man complained of back pain and swelling for 3 months, not responding to NSAIDs treatment and the swelling appear to grow bigger in the last 1 month. He underwent surgery to remove a tumour measuring 3cm. The microscopic morphology is shown above. The tumour is composed of interconnecting trabeculae of woven bone by plump osteoblast, set within loose edematous fibrovascular stroma. What is most likely diagnosis for this tumour?

a)

Chondroma

b)

Osteoblastoma

c)

Osteosarcoma

d)

Osteoclastoma