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Worksheets

Tumor Module

Total questions: 24

Worksheet time: 24mins

Name
Class
Date
1.

When performing an open incisional biopsy of a musculoskeletal neoplasm, which of the following principles does not apply?

a)

Dissection through intermuscular planes should be avoided

b)

A torniquet should not be used

c)

The incision should be placed longitudinally and in line with the intended future resection

d)

Hemostasis should be maintained

2.

Most common benign tumor of hand is

a)

Giant cell tumor

b)

Osteochondroma

c)

Enchondroma

d)

Aneurysmal Bone Cyst

3.

12 years girl, presented in OPD with history of fall from bed, complaining of pain in right leg. On examination right proximal leg is mild swellen and tender. Xray showed here. What is the next best step in the treatment of her pain?

a)

CT Scan right leg

b)

Incisional biopsy

c)

Extended curattage and grafting

d)

Manage conservatively i.e. analgesics, rest and observation.

4.

A 14 years boy presents with 6 months of knee pain and swelling. Radiograph and MRI are shown here. Biopsy showed chondroblats arranged in a cobblestone pattern. What is the most likely diagnosis?

a)

Chondrosarcoma

b)

Giant cell tumor

c)

UBC

d)

Malignant fibrous histocytoma

e)

Chondroblatoma

5.

You are asked to consult on a 8 years child in the emergency department with the pathological fracture shown here. In preparation for transfer to a sarcoma center for treatment , all of the following are correct steps in the child's management EXCEPT?

a)

Pain Management

b)

Hanging arm sling

c)

Tumor staging including bone scan, CT of chest, MRI of entire bone

d)

Consultation with pediatric oncology

e)

Tumor biopsy performed by interventional radiologist

6.

A 78 years old male with known metastatic renal cell carcinoma who presented in OPD with severe left arm pain and dificulty in lifting objects. His radiograph is shown here. What is the patient's Mirels score?

a)

7

b)

9

c)

10

d)

12

7.

A 8 years boy presents with knee pain and an effusion. Biopsy and staging show a distal femoral osteosarcoma with contamination of the knee joint. Which of the following treatment options will provide this child with the best chance of local control and the highest level of function?

a)

Through knee amputation

b)

Above knee Amputation

c)

Rotationplasty

d)

Extrarticular resection, endoprosthetic reconstruction and free flap coverage

8.

Which of the following factors portends the worst prognosis in a patient with an osteosarcoma of the distal femur?

a)

Age

b)

Size

c)

Location in proximal femur

d)

Skip metastasis

9.

25 years male presented in OPD with complain of pain in rigth leg for last two months. there is no history of trauma, fever. Pain increase with activity, worse at night and relieved by NSAID. Xray showed here. What will be your next step in management?

a)

Do MRI right leg with contrast

b)

Do CT scan right leg

c)

Incisional biopsy

d)

Surgical resection

10.

All of the following locations are common sites for Giant cell tumor of bone to occur Except

a)

Posterior elements of spine

b)

Distal femur

c)

Sacrum

d)

Distal radius

11.

A 19 years girl presents with dull right thigh pain for the last 2 months. Radiograph shown here and biopsy showed tumor cells with marked atypia producing lacey osteoid. What will be most appropriate definitive treatment?

a)

Intravenous antibiotic for 4 to 6 weeks

b)

Extended Curattage and bone grafting

c)

Extended curattage and bone cement placement

d)

Radiotherapy

e)

Neoadjuvant chemotherapy, wide mardin resection and adjuvant chemotherapy

12.

A 12 years old girl presents with an isolated distal femur osteosarcoma that extends into the soft tissue. Workup is negative for metastasis but biopsy reveals a high grade lesion. What is the stage of this tumor by the Musculoskeletal Tumor society system?

a)

II A

b)

I B

c)

II B

d)

III

13.

A 8 year old girl comes to the OPD with increasing thigh pain mostly at night. Radiograph shown here. The patients WBC and ESR are both elevated. Biopsy revealed sheets of monotonous small round blue cells. what is the most likely diagnosis?

a)

Osteosarcoma

b)

Ewings Sarcoma

c)

Osteomyelitis

d)

Chondrosarcoma

14.

16 years female presented to OPD with left shoulder pain. She is otherwise healthy and denies trauma. Radiograph and MRI images are shown here. Biopsy done which revealed blood filled spaced without endothelial lining. What is your diagnosis?

a)

Fibrous Dysplasia

b)

Aneurysmal Bone cyst

c)

Unicameral bone cyst

d)

Giant cell tumor

15.

A 45 years woman presents with painful knee that has rapidly progressed in the last 9 months. MRI image is shown here. The treating surgeon elects to proceed with a biopsy. How should the biopsy be performed?

a)

Transverse incisional biopsy through anterior approach

b)

Longitudinal incisional biopsy through lateral approach

c)

Transverse incional biopsy through posterior approach

d)

Longitudinal incional biopsy through medial approach

16.

A 40 years female presents with 6 months of wrist pain and swelling. she is otherwise healthy and denies trauma.. Radiograph is shown here. What is the most likely diagnosis?

a)

Unicameral Bone Cyst

b)

Aneurysmal Bone cyst

c)

Giant cell tumor

d)

Fibrous dysplasia

17.

A 58 years male is referred to your clinic for a sacral mass found on a lumbar spine MRI. He brought a biopsy report that was performed at an outside hospital that states "primary malignant bone tumor of notochordal remnant cells". There is no distant disease. Which of the following describes the best treatment strategy for this patient?

a)

Tumor debulking and chemotherapy

b)

Wide Surgical resection

c)

Radiation therapy

d)

Observation with serial imaging

18.

Soft tissue sarcoma commonly metastasize to the

a)

Liver

b)

Lung

c)

Bone

d)

Brain

19.

A 23 years male reports a firm, immobile mass behind his tibia that creates pain when he walks long distances or uses stairs. He reports no night pain or constitutional symptoms. His WBC, LDH and Alk Phos are normal. Radiographs and MRI are shown here. What is the next most appropriate step in management?

a)

Neoadjuvant chemotherapy followed by surgical resection followed by adjuvant chemotherapy

b)

Radical margin resection with allograft prosthetic reconstruction

c)

Marginal resection

d)

External beam irridiation

20.

Which of the following bone tumor has Sun-ray appearence on Xray

a)

Ewings Sarcoma

b)

Osteosarcoma

c)

Osteoblastoma

d)

Chondroarcoma

21.

Which of the following tumors has the favourable preoperative downstaging role with Denosumab?

a)

Osteosarcoma

b)

Ewings Sarcoma

c)

Giant cell tumor

d)

Rhabdomyosarcoma

22.

A 36 years female presented in OPD with a left sided pelvic mass. biopsy already has been done somewhere else which showed hypercellular stroma with malignant cells and abundant cartilaginous matrix. Radiograph is shown here. Which of the following risk factors is associated with poorer prognosis for this tpe of tumor?

a)

Female gender

b)

Biopsy performed at a tumor center

c)

Negative resection margins

d)

Pelvis location

23.

Following preoperative chemotherapy, the percent of tumor necrosis has been shown to be of prognostic value for which of the following tumors?

a)

Giant cell tumor

b)

Chondrosarcoma

c)

Osteosarcoma

d)

Metastatic adenocarcinoma

24.

A 45 years male presents with a 6 month history of recurrent knee effusion and pain. There is no history of trauma. Exam shows a lrge joint effusion, decrease range of motion and a odularity surrounding the knee. MRI and arthroscopic pictures are shown here. what is the most likely diagnosis?

a)

Synovial sarcoma

b)

Synovial Chondromatosis

c)

Haemophilic arthropathy

d)

Pigmented villonodular synovitis