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Disease Storyline #2 Quiz

Total questions: 22

Worksheet time: 11mins

Name
Class
Date
1.

What can cancer cells do that normal cells cannot?

a)

they do everything the same

b)

they regenerate their telomeres, preventing them from aging

c)

they go through cellular division

d)

they grow

2.

True or False: Having healthy tumor suppressor genes is an advantage to fighting cancer.

a)

True

b)

False

3.

What is the complementary mRNA strand for the following DNA strand? TGA GTT TGT

a)

CAU CAA ACA

b)

ACU CGG ACA

c)

ACU CAA ACA

d)

ACT CAA ACA

4.

What is the mutation present in the following DNA strands?

TGA ATG GAC

TGA ACG GAC

a)

insertion of Cytosine

b)

deletion of Thymine

c)

substitution of Cytosine to Adenine

d)

substitution of Thymine to Cytosine

5.

What gene is often mutated to become inactive which can lead to cancers?

a)

p57

b)

EVR 1

c)

p53

d)

telomerase

6.

The scientist who said that cells lose DNA with each cell division and therefore will only divide a finite number of times is

a)

James Watson

b)

Leonard Hayflick

c)

Albert Einstein

d)

Rachel Carson

7.

What purpose do telomeres serve (select all that apply)?

a)

they protect the coding regions of chromosomes

b)

they code for proteins

c)

they help cancer progress

d)

they help maintain genome stability

8.

Use the codon wheel to determine the amino acid sequence below:

AUU CCG UUG GAG

a)

Methionine - Leucine- Leucine - Aspartic Acid

b)

Isoleucine - Proline - Leucine -Aspartic Acid

c)

Isoleucine - Proline - Leucine -Glutamic Acid

d)

Asparagine - Arginine - Phenylalanine - Glycine

9.

A nitrogen base is lost from the healthy DNA strand. What do we call this mutation?

a)

substitution

b)

insertion

c)

point mutation

d)

deletion

10.

This repetitive DNA sequence, TTAGGG, found at the end of eukaryotic chromosomes is (a) ____

a)

DNA polymerase

b)

telomere

c)

p53

d)

cancer

11.

Suppose someone has more telomerase activity than normal, what would this indicate about that person's cells? (select all answers that apply)

a)

they could be cancerous

b)

their cells could be immortal

c)

their cells would die quickly

d)

they may have long telomeres

12.

What is apoptosis?

a)

necrosis

b)

phagocytosis

c)

programmed cell death

d)

inflammation of the cell

13.

In relation to the cell cycle and cancer, a mutation in this gene is like having your foot stuck on the gas pedal.

a)

oncogene

b)

tumor suppressor gene

c)

DNA repair gene

14.

How many more copies of p53 gene do elephants have compared to humans?

a)

2 times

b)

40 times

c)

20 times

d)

10 times

15.

What is the relationship between cancer rates and the body mass of animals?

a)

The larger the animals the higher the cancer rates

b)

The smaller the animal the lower the cancer rates

c)

There is no correlation between cancer rates and body size

d)

The small the animal the higher the cancer rates

16.

What are two potential contributing factors that may lead to high rates of cancer in sea lions? (Select all that apply)

a)

genetic factors

b)

obesity

c)

pollutants in the water

d)

age

17.

How is facial tumor disease spread between Tasmanian devils?

a)

biting

b)

virally passed on

c)

grooming

d)

through mating

18.

The Hayflick limit involves

a)

the size a cell can reach before dividing

b)

a cell dividing about 50 times before it reaches senescence

c)

telomeres lengthening with each cell division

d)

None of the choices

19.

In a healthy cell, if p53 identifies a mutation in the DNA of a cell it will

a)

destroy it

b)

not allow it to move to the next phase until it is repaired

c)

allow the cell to continue dividing

d)

attack and destroy the DNA

20.

If the DNA of a gene reads as follows what would the final amino acid sequence be?

CAC - TGA - TTA - ATG

a)

Histidine - Threonine - Lysine - Glycine

b)

Histidine - Stop - Lysine - Methionine

c)

Valine - Threonine - Asparagine - Tyrosine

21.

Telomeres ___ with each cell division

a)

lengthen

b)

shorten

22.

True/False: the more copies of p53 an organism has the more likely they will develop cancer.

a)

True

b)

False