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Melanin: Pedigrees, Punnett Squares, Protein Syn. & Mutations

Total questions: 42

Worksheet time: 34mins

Name
Class
Date
1.
What do we use pedigrees for?
a)

To look at families

b)

To make determinations about the offspring

c)

To track traits in families

d)

Nothing

2.

The phenotype of an individual is the ____.

a)

genetic make up of an individual

Ex) AA

b)

physical traits shown by an individual

Ex) curly hair

c)

the alleles

d)

a picture of the chromosomes

3.
What does an open circle represent?
a)
Not Affected Male
b)
Not Affected Female
c)
Affected Male
d)
Affected Female
4.

This picture shows____

a)

male & female connected by a marriage line

b)

male and female siblings

c)

grandparents

d)

offspring

5.
What does a filled in square represent?
a)
Not affected Female
b)
Not affected Male
c)
Affected Male
d)
Affected Female
6.
Looking at this pedigree, how many family members have the disease?
a)

6

b)

7

c)

All

d)

None

7.

Using the pedigree tracking albinism through this family, what are the genotypes for

individuals 1 & 2?

a)

person 1 = AA

person 2 = AA

b)

person 1 = Aa 

person 2 = AA

c)

person 1 = Aa 

person 2 = Aa

d)

person 1 = aa

person 2 = aa

8.

Which of the following are the children of individuals 1 & 2?

a)

3,4,5,6,7,8,9

b)

3,5,6,9

c)

4,7,9

d)

4,5,6,7,8

9.

The pedigree here shows the inheritance of free earlobes and attached earlobes in five generations of a family. Attached earlobes are caused by a recessive allele (f).

What would the genotype be of individual 14? 

a)

Ff

b)

ff

c)

F -

d)

FF

10.

A genotype is the _____.

a)

genetic make up of an individual

Ex) Tt

b)

a picture of the chromosomes

c)

what the individual looks like

d)

the physical trait shown by an individual

Ex) Brown Hair

11.

Aa, DD, Bb, yy are all examples of ___

a)

genotypes

b)

phenotypes

12.

An allele is _____

a)

one form of a gene.

b)

found on a centromere. 

c)

a genetic mutation.

d)

a physical characteristic. 

13.

Organisms that have two identical alleles for a particular trait are said to be _____.

a)

hybrid.

b)

homozygous. 

c)

heterozygous.

d)

dominant. 

14.

Combination of one dominant allele and one recessive allele

is referred to as _____.

a)

homozygous dominant 

b)

heterozygous

c)

homozygous recessive 

d)

dominant

15.

The combinations of RR and Rr will always show up as_____

a)

a recessive phenotype 

b)

a dominant phenotype 

c)

neither phenotype

d)

both phenotypes

16.

A Punnett square is used to determine _____.

a)

the probable outcome of a cross. 

b)

the actual outcome of a cross. 

c)

only genotypes.

d)

only phenotypes.

17.

The likelihood that a particular event will happen is called _____.

a)

test cross. 

b)

occurrence. 

c)

probability.

d)

monohybrids.

18.

With the trait of albinism, what would the genotypic ratio be for the children of parents that are  AA x Aa?

a)

2 normal pigmentation : 2 albino

b)

3 normal pigmentation : 1 albino

c)

2 AA : 2 Aa

d)

1 AA : 2 Aa : 1 aa

19.

With the trait of albinism, what would be the phenotypic ratio for the children of parents that were Aa x aa?

a)

2 Aa : 2 aa

b)

1 AA : 2 Aa : 1 aa

c)

2 normal pigmentation : 2 albino

d)

3 normal pigmentation : 1 albino

20.
If B = brown hair and b = blonde hair, what is the probability of brown hair?
a)
25%
b)
50%
c)
0%
d)
75%
21.

What is a mutation?

a)

a random change in the DNA

b)

a random change in the amino acid chain

c)

an error that occurs when the mRNA is made

22.

What amino acid corresponds to the following mRNA?

AGU

a)

Serine

b)

Valine

c)

Glycine

d)

Proline

23.

The process to go from mRNA to a protein is called

a)

Transcription

b)

Translation

c)

Replication

24.

The process to go from DNA to mRNA is

a)

Transcription

b)

Translation

c)

Replication

25.

Choose the nucleotide sequence of the RNA strand that would be complementary to the following strand:

GTAGTCA

a)

UATUAGA

b)

CAUCAGU

c)

ACGACTG

d)

CATCAGT

26.
Hair colour is an example of
a)
genotype
b)
phenotype
27.
A long chain of amino acids is a/an
a)
protein
b)
nucleic acid
c)
tRNA
d)
mRNA
28.
The exact genetic makeup of an organism, such as RR, Tt, PP is its?
a)
phenotype
b)
dominance
c)
genotype
d)
trait
29.

What is the central dogma of biology?

a)

RNA--> DNA --> Protein

b)

Protein --> RNA --> DNA

c)

DNA-->RNA-->Protein

d)

RNA --> RNA --> RNA

30.

Insertion, deletion, and substitution are all examples of a change in a genetic sequence which is also referred to as (a)

a)

Gene

b)

Amino Acid

c)

Ribose

d)

Mutation

31.

The change in the second codon of DNA sequence from GAA to GAG does not affect the amino acid sequence. This is an example of ........................................

a)

Nonsense mutation

b)

Missense mutation

c)

Silent Mutation

d)

Frameshift Mutation

32.

What type of mutation is this?

a)

STOP (nonsense) mutation

b)

Missense mutation

c)

Silent mutation

d)

Frameshift mutation

33.

A type of mutation that affect every codon beyond the point of mutation.

a)

Point Mutation

b)

Silent Mutation

c)

Nonsense Mutation

d)

Frameshift Mutation

34.

How does the structure of DNA determine the structure of a protein?

a)

DNA --> RNA --> codes for amino acids--> amino acids make protein--> protein makes phenotype

b)

RNA --> DNA --> protein makes phenotype --> codes for amino acid --> amino acid makes protein

c)

Codes for amino acid --> DNA --> amino acid makes protein --> RNA --> protein makes phenotype

35.

What type of mutation involves substituting a DNA base with a different base?

a)

point mutation

b)

frameshift mutation

c)

silent mutation

d)

chromosomal mutation

36.

What type of mutation involves adding or deleting bases from the DNA, which results in new codons (a shift in the reading of the codons)?

a)

point mutation

b)

frameshift mutation

c)

silent mutation

d)

chromosomal mutation

37.

Match the following

a)

1.

Substitution Point Mutation

b)

2.

Insertion Frameshift Mutation

c)

3.

Deletion Frameshift Mutation

38.

What is the role of mRNA

a)

Carry an amino acid to the ribosome

b)

Copy the instructions from DNA and carry it out of the nucleus

c)

Make up the ribosomes

39.

Where does Transcription occur

a)

Nucleus

b)

Ribosome

c)

ER

d)

Mitochondria

40.

Where does Translation occur?

a)

Nucleus

b)

Ribosome

c)

ER

d)

Chloroplast

41.
The information about an organism’s heredity is stored in its DNA. DNA is located in the cell’s _____________________. 
a)
mitochondria
b)
lysosomes
c)
nucleus
42.

Place the steps below in the correct order.

a)

transcription

b)

mRNA travels to the ribosome

c)

translation

d)

new protein is created

1)
2)
3)
4)