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WorksheetsBIOCEL 01
Total questions: 20
Worksheet time: 11mins
Name
Class
Date
1.
The ___ performs most of the cell’s intermediate metabolism, which focuses primarily on ______.
a)
cytosol / catabolism
b)
mitochondrion / anabolism
c)
mitochondrion / aerobic glycolysis
d)
mitochondria / oxidative phosphorylation (OXPHOS)
e)
cytosol / anabolism
2.
They are non-membrane bound organelles:
a)
Free ribosomes and cytoskeleton
b)
Fixed ribosomes and rough endoplasmic reticulum
c)
Golgi apparatus and peroxisomes
d)
Lysosomes and mitochondria
e)
Vacuoles and vesicles
3.
Example in which the transport protein molecule becomes embedded in the lipid bilayer.
a)
Protein traffic from the cytosol into the ER lumen
b)
Protein traffic from the cytosol into the nucleus
c)
Intracellular diffusion of small protein molecules
d)
Vesicular transport
e)
Protein traffic from ER to Golgi apparatus
4.
______ are responsible for cleaving the stretch amino acid sequence 'sorting signals' from N-terminals of proteins once the sorting process is completed in eukaryotic cells.
a)
All are correct
b)
Signal peptidases (SPases)
c)
Ubiquitous membrane-anchored serine proteases
d)
Endoplasmic reticulum signal peptidase (ER SPase)
e)
Mitochondrial processing peptidase (MPP)
5.
Evolutionary theory in which eukaryotic cell's organelles (eukaryogenesis) came from a symbiotic origin
a)
All are correct
b)
Xenogenus theory
c)
Merging theory
d)
Exogenous theory
e)
Endosymbiotic theory
6.
A eukaryotic cell organelle that depicts a paradigmatic endogenous theory scenario
a)
Peroxisome
b)
Golgi apparatus
c)
Lysosome
d)
Ribosome
e)
Cytoskeleton
7.
The evolutionary process that played a major role in the adaptation of organisms to different environments
a)
All answers are correct
b)
Morphological differences between the same organelles in different species
c)
Different enzymatic functions in the same organelles in different cell-types
d)
Organelle's proteome variabillity across tissues and conditions
e)
Re-targeting or relocalization of proteins to different compartments
8.
A major process of communication between the compartments that connect the cell with its environment is achieved by:
a)
Vesicular transport
b)
Gated transport
c)
Protein translocation
d)
Free diffusion of small molecules
e)
All answers are correct
9.
Membrane trafficking can be divided into two basic pathways based on the direction of travel, exocytosis and endocytosis. The __________ is/are an example of the endocytic pathway.
a)
All answers are correct
b)
macropinocytosis
c)
phagocytosis
d)
autophagy
e)
Uptake of vitamins, iron or cholesterol
10.
The_________ vesicles mediate retrograde transport within the Golgi and towards the ER
a)
Coat protein I (COPI)
b)
Clathrin-coated
c)
Coat protein II (COPII)
d)
protein complexes-caveolins
e)
All answers are correct
11.
Most vesicles traffic along microtubules using kinesin, dynein, myosin II and Myosin V motors to move along the actin network. Those, the __________ is responsible for moving vesicles throughout the cell.
a)
cytoskeleton
b)
Protein translocation
c)
Gated transport
d)
Signal peptidases (SPases)
e)
Ubiquitous membrane-anchored serine proteases
12.
The _______ proteins dock the transport vesicle at the correct acceptor compartment (membrane location) & catalyze membrane fusion (the final step in cargo delivery).
a)
SNAREs
b)
Rab
c)
Kinesin
d)
Complexes-caveolins and cavins.
e)
All answers are correct
13.
Found in all cells, there are three exocytosis pathways. The __________ deliver freshly synthesized membrane lipids and proteins, and soluble secretory proteins from a retrograde movement through the Golgi network directly to the plasma membrane were secretory vesicles accumulate and concentrate waiting for an external signal to fuse with the plasma membrane (e.g. the synapse in neurons).
a)
Regulated secretory pathway
b)
Lysosomal secretory pathway
c)
Constitutive secretory pathway
d)
Endosomal secretory pathway
e)
All answers are correct
14.
In polarized cells, proteins can be moved from one side of the cell to the other, via the ___________.
a)
Transcytotic pathway
b)
Lysosomal pathway
c)
Constitutive pathway
d)
Endosomal pathway
e)
All answers are correct
15.
Membrane trafficking can be divided into two basic pathways based on the direction of travel, exocytosis & endocytosis. Membrane receptors are mainly internalized via _______.
a)
Clathrin-coated vesicles
b)
Kinesin proteins
c)
Rab-coated vesicles
d)
Signal peptidases (SPases)
e)
All answers are correct
16.
_______ is a bidirectional process where cargo molecules move from one polarized cell's side to the other, a clear example of cross-talk between the exocytic and endocytic pathways.
a)
Transcytosis
b)
Passive transport
c)
Passive diffusion
d)
Active transport
e)
Late Endosome-to-Plasma Membrane
17.
After a virus attaches to its host cell, it must find some way to enter the cell. Viruses are internalized into the cell by______ pathway to finally cause infections.
a)
All answers are correct
b)
via phagocytosis
c)
via clathrin and caveolae-mediated endocytosis
d)
via raft-dependent endocytosis
e)
via clathrin and caveolae-independent endocytic pathways
18.
Clathrin, caveolae and raft-mediated endocytosis depend on the ______ for pinching off the newly formed vesicles from the membrane of the cell or a cellular compartment.
a)
GTPase dynamin
b)
Kinesin proteins
c)
Rab GTPases
d)
Actin
e)
Myosin
19.
Is/are a vesicular process(es) regulated by GTPases cascades
a)
All answers are correct
b)
Vesicle coat assembly
c)
Vesicle formation and cargo sorting
d)
Vesicle membrane curvature into spherical buds
e)
Vesicle fission and un-coating (disassembly)
20.
Is/are key components of the machinery involved in vesicular transport?
a)
All answers are correct
b)
Coat and motor proteins
c)
Rab GTPases
d)
Cargo receptors
e)
SNARE proteins
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