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Dr Heemer lung cancer

Total questions: 11

Worksheet time: 6mins

Name
Class
Date
1.

Which of the following is the most common cause of cancer-related deaths in the US?

a)

Breast

b)

Lung

c)

Colorectal

d)

Prostate

2.

What is the difference between Non-Small Cell Cancer (NSCLC) and Small Cell Lung Cancer (SCLC)

a)

SCLC overexpresses CKIT, a protein tyrosine kinase- receptor that is specific for stem cell factor

b)

SCLC has mutations in Epidermal growth factor receptor EGFR)

c)

SCLC has mutations in Anaplastic lymphoma kinase (ALK)

3.

Select all the drugs that target the EML4-ALK pathway, important for treatment of NSCLC adenocarcinoma .

a)

Crizotinib

Ceritinib

Alectinib

Brigatinib

b)

Erlotinib

Gefitinib

Afatinib

Dacometinib

Osimertinib

c)

All of them

4.

EGFR inhibitors used to treat NSCLC and offer potential method of lung cancer chemoprevention

a)

Erlotinib

Gefitinib

Afatinib

Dacometinib

Osimertinib

b)

Erlotinib

Gefitinib

c)

Crizotinib

Ceritinib

Alectinib

Brigatinib

5.

Slower growth rate and doubling time than…

a)

SCLC

b)

NSCLC

c)

ClSS

d)

LCLs

6.

Bevacizumab should be used for the treatment of non-small cell lung cancer with which of the following

a)

Nonsquamous histology

b)

Squamous histology

c)

It’s not use in lung cancer treatment

7.

A 76 YO patient is diagnosed with nonsmall cell lung cancer with expression rearrangements This patient is a candidate for which of the following targeted agents for the treatment of lung cancer?

a)

Crizotinib

Enterctinib

b)

Crizotinib

Erlotinib

c)

Vandetanib

Bevacizumab

d)

Crizotinib

Bevacizumab

8.

Which is true regarding NSCLC

a)

Moderately sensitive to radiation

Low sensitivity to chemotherapy

Squamous cell histology

Slower growing

b)

none of the above

c)

Relatively sensitive to chemotherapy and radiation

d)

all of the above

9.

A 69 YO male patient is diagnosed with extensive stage small-cell lung cancer. This patient's social history includes smoking (30pack / y ear) Patient's other disease states include DM and hypertension. All patient's labs are WNL except SCr = 1.7 and estimated creatinine clearance about 34mL / m in The patient is starting treatment today for small-cell lung cancer (extensive stage)

a)

Cisplatin and etoposide

b)

Carboplatin and etoposide

c)

Cyclophosphamide, etoposide and Crizotinib

d)

Doxorubicin and etoposide

10.

A 69 YO male patient is diagnosed with extensive stage small-cell lung cancer. This patient's social history includes smoking (30pack / y ear) Patient's other disease states include DM and hypertension. All patient's labs are WNL except SCr = 1.7 and estimated creatinine clearance about 34mL / m in The patient is starting treatment today for small-cell lung cancer (extensive stage)

Which is most likely the risk factor for this patient SCLC?

a)

Chronic renal failure

b)

Hypertension

c)

History of smoking

d)

DM diagnosed

11.

Difference between Cisplatin and carboplatin

a)

Caboplatin cause more nausea vomiting and nephrotoxicity

b)

Carboplatin causes less nausea and vomiting, nephrotoxicity, neurotoxicity, but more myelosuppression (thrombocytopenia)

c)

Cisplatin causes less nausea and vomiting, nephrotoxicity, neurotoxicity, but more myelosuppression (thrombocytopenia)