WorksheetsDr Heemer lung cancer
Total questions: 11
Worksheet time: 6mins
Which of the following is the most common cause of cancer-related deaths in the US?
Breast
Lung
Colorectal
Prostate
What is the difference between Non-Small Cell Cancer (NSCLC) and Small Cell Lung Cancer (SCLC)
SCLC overexpresses CKIT, a protein tyrosine kinase- receptor that is specific for stem cell factor
SCLC has mutations in Epidermal growth factor receptor EGFR)
SCLC has mutations in Anaplastic lymphoma kinase (ALK)
Select all the drugs that target the EML4-ALK pathway, important for treatment of NSCLC adenocarcinoma .
Crizotinib
Ceritinib
Alectinib
Brigatinib
Erlotinib
Gefitinib
Afatinib
Dacometinib
Osimertinib
All of them
EGFR inhibitors used to treat NSCLC and offer potential method of lung cancer chemoprevention
Erlotinib
Gefitinib
Afatinib
Dacometinib
Osimertinib
Erlotinib
Gefitinib
Crizotinib
Ceritinib
Alectinib
Brigatinib
Slower growth rate and doubling time than…
SCLC
NSCLC
ClSS
LCLs
Bevacizumab should be used for the treatment of non-small cell lung cancer with which of the following
Nonsquamous histology
Squamous histology
It’s not use in lung cancer treatment
A 76 YO patient is diagnosed with nonsmall cell lung cancer with expression rearrangements This patient is a candidate for which of the following targeted agents for the treatment of lung cancer?
Crizotinib
Enterctinib
Crizotinib
Erlotinib
Vandetanib
Bevacizumab
Crizotinib
Bevacizumab
Which is true regarding NSCLC
Moderately sensitive to radiation
Low sensitivity to chemotherapy
Squamous cell histology
Slower growing
none of the above
Relatively sensitive to chemotherapy and radiation
all of the above
A 69 YO male patient is diagnosed with extensive stage small-cell lung cancer. This patient's social history includes smoking (30pack / y ear) Patient's other disease states include DM and hypertension. All patient's labs are WNL except SCr = 1.7 and estimated creatinine clearance about 34mL / m in The patient is starting treatment today for small-cell lung cancer (extensive stage)
Cisplatin and etoposide
Carboplatin and etoposide
Cyclophosphamide, etoposide and Crizotinib
Doxorubicin and etoposide
A 69 YO male patient is diagnosed with extensive stage small-cell lung cancer. This patient's social history includes smoking (30pack / y ear) Patient's other disease states include DM and hypertension. All patient's labs are WNL except SCr = 1.7 and estimated creatinine clearance about 34mL / m in The patient is starting treatment today for small-cell lung cancer (extensive stage)
Which is most likely the risk factor for this patient SCLC?
Chronic renal failure
Hypertension
History of smoking
DM diagnosed
Difference between Cisplatin and carboplatin
Caboplatin cause more nausea vomiting and nephrotoxicity
Carboplatin causes less nausea and vomiting, nephrotoxicity, neurotoxicity, but more myelosuppression (thrombocytopenia)
Cisplatin causes less nausea and vomiting, nephrotoxicity, neurotoxicity, but more myelosuppression (thrombocytopenia)
