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MMR/FLU/DENGUE

Total questions: 30

Worksheet time: 15mins

Name
Class
Date
1.

The nucleocapsid protein of paramyxoviridae participates in viral envelope formation.

a)

true

b)

false

2.

Classic CPE in paramyxovirus infection

a)

cell lysis

b)

syncytia

c)

INCLUSIONS

3.

Mumps is characterized by the suppurative enlargement of one or both salivary glands.

a)

true

b)

false

4.

It is difficult to control mumps transmission due to the presence of virus in saliva before clinical symptoms occur.

a)

true

b)

false

5.

Most sensitive method of detecting paramyxoviruses

a)

ELISA

b)

CELL CULTURE

c)

RT-PCR

6.

identify the structure

a)

Henderson-Patterson

b)

Cowdry A

c)

Warthin-Finkeldy

7.

Term used to described the rashes observed during rubeola.

a)

vesicular

b)

macular

c)

exanthem

d)

maculopapular

8.

It is a pathognomonic symptom for rubeola that is seen on  the buccal mucosa

a)

herpangina

b)

hand foot & mouth disease

c)

forchheimer spots

d)

koplik spots

9.

It is the only member of the genus rubivirus.

a)

mumps virus

b)

rubeola virus

c)

rubella virus

10.

This condition belongs to which group of  CRS symptoms :

a)

GROUP A

b)

GROUP B

c)

GROUP C

11.

It is the only influenza viral type known to cause flu pandemics

a)

A

b)

B

c)

C

12.

Hemagglutinin derives its name from its ability to agglutinate erythrocytes.

a)

TRUE

b)

FALSE

13.

Cleavage of neuraminidase must occur so that the viral attachment is successful.

a)

TRUE

b)

FALSE

14.

It is an abrupt type of change due to genetic reassortment with an unrelated strain.

a)

ANTIGENIC SHIFT

b)

ANTIGENIC DRIFT

15.

Antigenically stable influenza serotype .

a)

A

b)

B

c)

C

16.

It is the surface antigen of influenza virus that facilitates release of virions from infected cell surfaces.

a)

HEMAGLUTININ

b)

NEURAMINIDASE

c)

FUSION PROTEIN

17.

Existing vaccines are continually being rendered obsolete as the viruses undergo antigenic drift and shift.

a)

TRUE

b)

FALSE

18.

Antivirals can be used to treat flu?

a)

true

b)

false

19.

Severity of flu illness and severity of flu season are the same and do not vary.

a)

true

b)

false

20.

Changes in hemagglutinin and neuraminidase of the flu virus occur _________.

a)

dependently

b)

independently

c)

interdependently

21.

The chikungunya virus belongs to which group of viruses?

a)

Arbovirus

b)

Togavirus

c)

Flavivirus

d)

paramyxovirus

22.

What role does Aedes aegypti and Aedes albopictus play in the replication of CHIKV?

a)

major host

b)

principal vectors

c)

intermediate host

23.

Alphaviruses have 3 or 4 major structural polypeptides, two of which are glycosylated.

a)

true

b)

false

24.

CHIKV directly triggers the activation of an innate immune response.

a)

true

b)

false

25.

The most specific serologic assays for CHIKV detect virus-specific _______ .

a)

IgM

b)

IgG

c)

cytopathic effect

26.

Mother to child transmission of dengue is impossible .

a)

true

b)

false

27.

DENV viremia occurs within :

a)

3-14 days

b)

24 hours

c)

5-7 days

d)

immediately after mosquito bite

28.

The rise and fall of body temperature during DENV infection is described as:

a)

wave-like

b)

crescendo

c)

saddleback

29.

A single alphavirus or flavivirus infection by one member of the group, antibodies to other members may also appear.

a)

true

b)

false

30.

Flaviviruses are spherical, _______ in diameter with a positive-sense, single-stranded RNA, 11 kb in size.

a)

140–160 nm

b)

60- 140 nm

c)

40-60 nm

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