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Worksheets

Biotechnology

Total questions: 19

Worksheet time: 12mins

Name
Class
Date
1.

What is the purpose of restriction enzymes?

a)

To join fragments of DNA

b)

To cut DNA at specific recognition sites

c)

To amplify DNA sequences

d)

To separate DNA fragments according to size

2.

What is the function of DNA ligase?

a)

To join fragments of DNA

b)

To cut DNA at specific recognition sites

c)

To amplify DNA sequences

d)

To separate DNA fragments according to size

3.

What is the function of a plasmid in DNA cloning?

a)

Amplifying DNA segments

b)

Cutting DNA at specific sites

c)

Ligating DNA fragments

d)

Serving as a vector to carry DNA into host cells

4.

What is the term for the resulting DNA molecule when two different DNA fragments are joined together in DNA cloning?

a)

Recombinant DNA

b)

Replicated DNA

c)

Amplified DNA

d)

Mutated DNA

5.

What is the purpose of bacterial transformation in DNA cloning?

a)

To cut and paste DNA fragments

b)

To amplify DNA sequences

c)

To join fragments of DNA

d)

To introduce foreign DNA into bacteria

6.

What is the goal of PCR?

a)

To cut DNA at specific recognition sites

b)

To join fragments of DNA

c)

To amplify a specific DNA region

d)

To separate DNA fragments according to size

7.

What is denaturation in the PCR process?

a)

The cooling of the reaction mixture

b)

The separation of DNA strands by heating

c)

The addition of primers to the reaction

d)

The final step in PCR amplification

8.

What is the typical temperature range for the denaturation step in PCR?

a)

37-42°C

b)

50-60°C

c)

72-75°C

d)

90-95°C

9.

What is the purpose of the extension step in PCR?

a)

To separate DNA strands

b)

To cool the reaction mixture

c)

To synthesize new DNA strands

d)

To add primers to the reaction

10.

How many cycles of denaturation, annealing, and extension are typically performed in a PCR reaction?

a)

1 cycle

b)

5 cycles

c)

20-40 cycles

d)

90-100 cycles

11.

What is the purpose of gel electrophoresis?

a)

To cut DNA at specific recognition sites

b)

To join fragments of DNA

c)

To amplify DNA sequences

d)

To separate DNA fragments according to size

12.
In gel electrophoresis, the largest DNA fragment will appear
a)
closest to the starting wells
b)
farthest from the starting wells
c)
three quarters away from the starting wells
d)
it depends on how many fragments there are
13.
Why do the fragments of DNA in gel electrophoresis travel away from the negative electrode?
a)

DNA is negatively charged and attracted to the positive end of the unit

b)

DNA is positively charged and attracted to the negative end of the unit

c)

the agarose gel is negatively charged

d)
the agarose gel is positively charged
14.
Based on these results whose blood was found in the blood stain at the crime scene?
a)
Bob
b)
Sue
c)
John
d)
Lisa
15.
Why do bacteria have restriction enzymes?
a)
To prevent being infected by viruses
b)
To help DNA get into the cell
c)
To be able to grow in an incubator
d)
They don't - viruses have restriction enzymes
16.

Which RE's from above make blunt cuts?

a)

Alul

b)

HaeIII

c)

BamHI

d)

HindIII

e)

EcorRI

17.

Which RE's from above make sticky cuts?

a)

Alul

b)

HaeIII

c)

BamHI

d)

HindIII

e)

EcorRI

18.

Which of the following is NOT a component of a DNA sequencing reaction?

a)

DNA template

b)

DNA polymerase

c)

Dideoxynucleotides (ddNTPs)

d)

Deoxynucleotides (dNTPs)

e)

Radioactive isotopes

19.

What is the role of dideoxynucleotides (ddNTPs) in DNA sequencing?

a)

They initiate DNA synthesis

b)

They terminate DNA synthesis at specific bases

c)

They elongate the DNA strands

d)

They repair DNA damage