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Worksheets

DNA s

Total questions: 31

Worksheet time: 20mins

Name
Class
Date
1.

The enzyme that restores the phosphodiester linkage between adjacent fragments in the lagging strand during DNA replication is

a)

DNA ligase

b)

primase

c)

reverse transcriptase

d)

helicase

2.

Who proved experimentally that DNA is genetic material?

a)

O. Avery and Colleagues

b)

J. Waston and F. Crick

c)

W. Arber and Colleagues

d)

G. Mendel

3.

The enzyme DNA dependent RNA polymerase catalyses the polymerisation reaction in ___________direction.

a)

only 5’ → 3’

b)

only 3’ → 5’

c)

both (a) and (b)

d)

none of these

4.

What is the function of primer

a)

To help DNA polymerase for initiation

b)

To help RNA polymerase for initiation

c)

To help DNA polymerase for termination

d)

To help RNA polymerase for termination

5.

DNA replication takes place at _________ phase of the cell

cyle.

a)

G1

b)

S

c)

G2

d)

M

6.

Which biomolecular group carries and passes on the hereditary information of the organism?

a)

a. carbohydrates

b)

b. lipids

c)

c. nucleic acids

d)

d. proteins

7.
If one series of bases reads: TTGACTAGG, then the complementary set of bases would read:
a)
TTGACTAGG
b)
AACTGATCC
c)
AATCGAACTT
d)
AAGTCATCC
8.

Which ones are purines?

a)

Adenine and Guanine

b)

Adenine and Thymine

c)

Cytosine and Guanine

d)

Cytosine and Thymine

9.

If a gene has 30 nucleotides, how many amino acids does it have?

a)

3

b)

10

c)

60

d)

90

10.

A piece of DNA was analysed and 15% of its nucleotides were adenine. What percentage would be uracil?

a)

0%

b)

15%

c)

35%

d)

70%

11.

If you have 40 adenine in a DNA molecule, how many thymine can you expect?

a)

10

b)

20

c)

40

d)

80

12.

What unique ability does DNA have because it is double-stranded?

a)

it serves as genetic material in all viruses

b)

it can serve as a template for its own copying

c)

it can move around the cells

d)

none of the choices

13.

The repeating units in both DNA and RNA are called

a)

hydrogen bonds

b)

nucleic acids

c)

nucleotides

d)

amino acids

14.

What is helix pitch?

4 lines
15.

Syn- and anti- conformations of nucleotide are related to

a)

Phosphodiester bond

b)

N-glycosidic bond

c)

Phosphoanhydride bond

d)

Hydrogen bond

16.

The bond stabilizing DNA between bases at horizontal plane is

a)

H-bond

b)

London dispersion force

c)

Hydrophobic interaction

d)

All of the above

17.

Which of the following statements is true?

a)

B-form of DNA is left handed helix

b)

Z-form of DNA is left handed helix

c)

A-form of DNA is left handed helix

d)

A-form of DNA is formed due to alternative purine pyrimidine ratio

18.

Factors NOT affecting DNA conformation type (either B, Z or A)

a)

Hydration level

b)

Temperature

c)

Salt concentartion

d)

Sequences of DNA

19.

Formation of A-DNA is favored by

a)

High hydration

b)

Low salt concentration

c)

Low hydration

d)

All of the above

20.

Deoxyribose sugar in B- form of DNA is of ______ conformation

a)

C1'-endo

b)

C2'-endo

c)

C3'-endo

d)

C5'-endo

21.

Watson and Crick built the model of _______ form of DNA

a)

B

b)

Z

c)

A

d)

C

22.

What is hyperchromic shift?

4 lines
23.

Which enzyme can denature DNA intracelluarly?

a)

Helicase

b)

Denaturase

c)

Nucleotidase

d)

All of the above

24.

DNA denaturation can not be done by

a)

Heat

b)

Sound wave

c)

change in H+ ion concentration in solution

d)

Chaotropic agents

25.
What is the function of nucleic acids?
a)
Stores energy
b)
Stores genetic information
c)
Movement
d)
Physical structure
26.

What is the shape of DNA?

a)

Double Hyperbola

b)

Paraolic

c)

Double Helix

d)

Linear

27.
Which is the correct pairing?
a)
A-C
b)
A-T
c)
A-G
28.

What sugar is found in DNA?

a)

Glucose

b)

Ribose

c)

Deoxyribose

d)

Fructose

29.

Which of the following is NOT part of a nucleotide?

a)

Nitrogenous Base

b)

Phosphate Group

c)

Pentose Sugar

d)

Fatty Acid

30.
What is the difference between DNA and RNA from the point of view of the nitrogenous bases that are present in their nucleotides?
a)
In DNA, nucleotides can be made up of A, T, C, G. In RNA, nucleotides can also contain A, C or G; however, instead of T, they contain U.
b)
Purine and Pyrimidine
c)
Pyrimidine: Thymine, Cytosine (Urical)
d)
DNA, RNA
31.
DNA and RNA are examples of...
a)
proteins
b)
nucleic acids
c)
carbohydrates
d)
lipids