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Unit 4: Cell Cycle and DNA Replication

Total questions: 33

Worksheet time: 23mins

Name
Class
Date
1.

Reorder the following phases of mitosis:

a)

b)

c)

d)

1)
2)
3)
4)
2.

Label the phases in the image shown.

3.

A student studying mitosis captures an image of cells from an onion root tip with a camera mounted on a microscope. Which events occur after the phase circled in the student's image?

a)

chromosomes condense

b)

paired chromosomes separate

c)

the nuclear membrane disappears

d)

chromosomes attach to spindle fibers

e)

the cytoplasm separates into two cells

4.

A student studying mitosis captures an image of cells from an onion root tip with a camera mounted on a microscope. Which events occur before the phase circled in the student's image?

a)

chromosomes condense

b)

paired chromosomes separate

c)

the nuclear membrane disappears

d)

chromosomes attach to spindle fibers

e)

the cytoplasm separates into two cells

5.

Scientists determined the total mass of DNA from a sample of animal cells. The masses of equal number of cells were taken during three different stages of the cell cycle. Stage I contains cells massed during G1 of the cell cycle.

 

Using the graphic below, indicate which stage is described by the statement:

 

"The cells have replicated their DNA, but have not completed mitosis and cytokinesis."

6.

The model of the cell cycle includes two arrows that represent a process in the cycle.

Fill in the blanks to describe the two arrows.

Arrow 1 represents -

Arrow 2 represents -

7.

Cells pass through a G2 checkpoint before entering mitosis. Ideally, if DNA damage is detected, the cells do not enter mitosis until the damage is repaired. Why is DNA damage repaired before cells enter mitosis?

a)

So that another round of DNA synthesis does not have to take place

b)

So that the chromosomes can align at the metaphase plate during mitosis

c)

So that the cytoplasm can be divided equally between the two daughter cells

d)

So that healthy daughter cells are produced, allowing the organism to continue growing

8.

Which of these properties is found only in cancer cells?

a)

Unregulated cell division

b)

Regulated gene expression

c)

Response to signals outside of the cell

d)

Presence of mitochondria

9.

Which of these is MOST LIKELY an indication that cells may have become cancerous?

a)

Cells undergoing slower rates of mitosis

b)

Cells with few or no mutations

c)

Cells not responding to checkpoints in the cell cycle

d)

Cells with decreased rates of protein synthesis

10.

Normal cells have a contact inhibition feedback mechanism that prevents the cells from replicating when other cells are touched. A diagram of cells with contact inhibition and cells without contact inhibition is shown. 

Which statement best describes what will happen to cells in an organism that lack contact inhibition?

a)

The cells will continue to grow, causing a tumor in the body.

b)

The cells will replicate normally, replacing body cells that die.

c)

The cells will replicate until the food supply for each cell is used, causing each cell to die.

d)

The cells will stop replicating once one layer is produced, as other body cells will crowd them out.

11.

Cells typically respond to DNA damage in three ways: by ceasing to grow and divide until the damage is repaired, by permanently ceasing to grow and divide, or by dying. In 2010 a group of scientists reported that a certain kind of immune reaction can cause DNA damage that leads to a fourth response. DNA damage can turn off genes involved in cell-signaling pathways. Turning off these genes can cause less-mature cells to divide too rapidly, often leading to the development of —

a)

tumors

b)

allergies

c)

hemophilia

d)

cardiovascular disease

12.

What components make up the backbone of a DNA molecule? Select 2 correct answers

a)

purines

b)

deoxyribose

c)

pyrmidines

d)

ribosomes

e)

phosphate groups

13.

In Texas Longhorn cattle, coat coloration is an inherited trait. What is the genetic basis of coat-color variation in Texas Longhorn cattle?

a)

Differences in the nucleotide sequences of genes

b)

Differences in the numbers of chromosomes in cells

c)

Differences in the diets of individual cattle

d)

Differences in the environmental conditions of different geographic areas

14.

During which phase does DNA replication occur?

a)

G1

b)

S

c)

G2

d)

M

15.

Two DNA molecules are the result of DNA replication.  Which of the following is a true statement regarding DNA replication? 

a)

Each DNA 

molecule has two 

new strands

b)

One of the DNA 

molecules has two new strands while 

the other has two original strands

c)

Each DNA 

molecule has two 

original strands

d)

Each new DNA 

molecule is made 

up of one new 

strand and one 

original strand.

16.

A student is investigating mitosis by examining detailed pictures of the process. The student wants to observe the formation of the nuclear envelope around the chromosomes. 

The student should focus on pictures of which phase of mitosis?

a)

Prophase

b)

Metaphase

c)

Anaphase

d)

Telophase

17.

Helicase is a protein that breaks the hydrogen bonds between complementary strands of DNA to allow DNA replication to occur. What type of biomolecule contains the code for making helicase?

a)

Carbohydrates

b)

Lipids

c)

Proteins

d)

Nucleic Acids

18.

Which of the following best describes the main purpose of the sequences of nitrogenous bases in DNA?

a)

Gives DNA the shape needed for translation

b)

Prevents mutations when coding for amino acids

c)

Forming the hydrogen bonds between bases

d)

Carries instructions for the traits of an organism

19.

Which of the following correctly identifies the proper nitrogen base pairing in DNA replication?

a)

A:T; G:C

b)

T:C; G:A

c)

T:U; C:G

d)

A:U; G:C

20.

The following represents a small section of one strand of DNA:

5’ TACATGTGGCCACT 3’

How should the complementary strand of DNA be represented?

a)

5’ TACATGTGGCCACT 3’

b)

3’ ATGTACACCGGTGA 5’

c)

5’ UTGTUCUCCGGTGU 3’

d)

3’ AUGUAGAGGCCUGA 5

21.

What part of the cell cycle results in daughter cells?

a)

Mitosis

b)

Prophase

c)

Cytokinesis

d)

G2 Checkpoint

22.

What occurs at G1?

a)

Chromatin 

condenses to form 

chromosomes

b)

Cleavage of 

cytoplasm and 

formation of cell

 plate

c)

Period of growth 

and development 

between mitotic 

divisions

d)

Nuclear membrane nucleolus, and 

chromatin fade

23.

In 1952, Rosalind Franklin took an X-ray photograph revealing the structure of DNA.  James Watson and Francis Crick follwed up on this discovery in 1953.  They discovered that the molecule has a shape specific to just that molecule.That shape can best be described as —

a)

a single strand containing 4 different bases that vary depending on the type of DNA

b)

ladder shaped, containing 5 nitrogenous bases that bond to one another

c)

triple stranded, with bonds between each strand holding the three strands togethe

d)

double stranded and twisted, with a base bonded to another base holding the strands together

24.

Of the following bases, which one is not found in DNA?

a)

Adenine

b)

Guanine

c)

Uracil

d)

Thymine

25.

A sample of human DNA is made up of approximately 30% adenine.  Based on this information, and the base pairing rules, approximately how much cytosine is found in human DNA?

a)

10%

b)

20%

c)

30%

d)

70%

26.

What are the products of photosynthesis?

a)

water

b)

oxygen

c)

glucose

d)

carbon dioxide

e)

light energy

27.

What are the products of cellular respiration?

a)

water

b)

oxygen

c)

glucose

d)

carbon dioxide

e)

chemical energy

28.

Based on the image, ______ is used as chemical energy to form ______, a source of energy for cellular processes.

(a)  

29.

What occurs inside of a cell while it performing the process of respiration?

a)

Sugar is broken down to generate adenosine triphosphate (ATP) molecules that are used for energy.

b)

The negative charge inside of the cell is used to increase the concentration chemicals inside of the cell.

c)

Light reactive chemicals combine carbon dioxide (CO2) and water to form glucose molecules that are stored as food.

d)

The cell membrane forms around air bubbles to create a vacuole that is used to separate the oxygen from the rest of the air.

30.

What occurs inside of a cell while it performing the process of photosynthesis?

a)

Sugar is broken down to generate adenosine triphosphate (ATP) molecules that are used for energy.

b)

The negative charge inside of the cell is used to increase the concentration chemicals inside of the cell.

c)

Light reactive chemicals combine carbon dioxide (CO2) and water to form glucose molecules that are stored as food.

d)

The cell membrane forms around air bubbles to create a vacuole that is used to separate the oxygen from the rest of the air.

31.
Which of the following conclusions can be drawn from this graph?
a)
The optimum pH of the enzyme is 6.6.
b)
The optimum pH of the enzyme is 5.8
c)
The enzyme’s activity increases as pH increases 5.0 to 9.0
d)
The enzyme’s activity is greater around pH of 8.0 .
32.

Which category of macromolecules do enzymes belong to?

a)

Carbohydrates

b)

Proteins

c)

Fats/Lipids

33.

What does an enzyme need in order to work properly?

a)

The right amount of oxygen & CO2

b)

The right temperature & amount of water

c)

The right temperature & pH

d)

The right temperature & pressure