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Non-Coding RNAs Quiz

Total questions: 16

Worksheet time: 8mins

Name
Class
Date
1.

What is the central dogma of molecular biology?

a)

DNA → mRNA → proteins

b)

mRNA → DNA → proteins

c)

Proteins → mRNA → DNA

d)

Proteins → DNA → mRNA

2.

What percentage of the human genome codes for proteins?

a)

50%

b)

10%

c)

98%

d)

2%

3.

What was the initial belief about the 'junk DNA' in the genome?

a)

It was involved in RNA synthesis

b)

It was considered useless

c)

It encoded important proteins

d)

It was responsible for gene regulation

4.

What are the two known classes of non-coding RNAs?

a)

Ribosomal RNAs and transfer RNAs

b)

Messenger RNAs and ribosomal RNAs

c)

Regulatory non-coding RNAs and housekeeping non-coding RNAs

d)

Small non-coding RNAs and long non-coding RNAs

5.

What is the function of transfer RNAs?

a)

Decoding the mRNA sequence and translating it into an amino acid sequence

b)

Carrying genetic information in the cell

c)

Regulating gene expression

d)

Building the structural components of ribosomes

6.

What is the most abundant RNA species in the cell?

a)

Ribosomal RNAs

b)

Transfer RNAs

c)

Messenger RNAs

d)

Small non-coding RNAs

7.

What is the function of microRNAs?

a)

Decoding the mRNA sequence

b)

Cutting up coding mRNAs

c)

Building ribosomes

d)

Transcribing DNA into mRNA

8.

What is the role of the non-coding RNA Xist?

a)

Repairing damaged DNA

b)

Inactivating one of the X chromosomes in female cells

c)

Enhancing protein synthesis

d)

Regulating gene expression in male cells

9.

What is the RNA World hypothesis?

a)

The idea that the first biomolecular processes were based on RNA

b)

The concept of using RNA as a data storage molecule

c)

The hypothesis that RNA is only involved in protein synthesis

d)

The theory that RNA is the most stable nucleic acid

10.

What are ribozymes?

a)

RNAs that regulate gene expression

b)

RNAs responsible for DNA replication

c)

RNAs involved in protein synthesis

d)

RNAs with a catalytic function like enzymes

11.

What is the function of cyclic AMP and cyclic di-GMP?

a)

Mediating signalling within or between cells

b)

Inactivating X chromosomes

c)

Decoding the mRNA sequence

d)

Building ribosomes

12.

What is the main challenge in studying the RNA World hypothesis?

a)

Lack of understanding of gene regulation

b)

Difficulty in sequencing the human genome

c)

Lack of direct evidence from 4 billion years ago

d)

Limited knowledge of non-coding RNAs

13.

What is the focus of the author's research project?

a)

The interaction between proteins and RNAs

b)

The sequencing of the human genome

c)

The role of non-coding RNAs in diseases

d)

The function of RNAs on the surface of chromosomes during cell division

14.

What is the significance of the story of junk DNA?

a)

It explains the evolution of the RNA World

b)

It challenges the central dogma of molecular biology

c)

It proves the uselessness of non-coding RNAs

d)

It highlights the complexity of the genome

15.

What is the importance of having an open mind in scientific research?

a)

To notice unexpected and beautiful things hidden behind nature's complexity

b)

To ignore the complexity of nature

c)

To adhere strictly to established theories

d)

To focus only on the known functions of biomolecules

16.

There was a lot of additional important information in this article. Do you think more information like this should be included in CSII?

a)

Definitely not. We already have a lot to learn

b)

No. What we have OK

c)

Maybe.

d)

Yes. It would be a more complete picture of RNA

e)

Definitely yes. We go too slowly and this is easy to add to what we are doing