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MI 3.1.3 When Cells Lose Control

Total questions: 14

Worksheet time: 11mins

Name
Class
Date
1.
Uncontrolled cell division is stopped by...
a)
tumor suppressor genes
b)
oncogenes
2.
Which is an example of a tumor suppressor gene?
a)
apoptosis
b)
proto-oncogenes
c)
p53
d)
oncogenes
3.

When is apoptosis initiated?

a)

When DNA damage is repaired.

b)

When cells are removed from the cell cycle.

c)

When DNA damage cannot be repaired.

4.
Proto-oncogenes can mutate into...
a)
oncogenes
b)
tumor suppressor genes
c)
DNA repair proteins
5.

Random errors in gene replication that lead to a change in the sequence of DNA

a)

Mutations

b)

Cell Cycle Checkpoints

c)

Mitosis

6.

What is apoptosis?

a)
The process of cell mutation
b)
The process of cell division
c)
The process of programmed cell death
d)
The process of cell growth
7.

What is the purpose of the cell cycle checkpoints?

a)

To make sure the cell isn't duplicating too fast

b)

They were there by chance and happen to help reduce the chances of cancer

c)

To make sure that all parts of the cell are healthy to avoid mutations

8.

What is osteosarcoma?

a)
A type of bone cancer
b)

A type of blood cancer

c)

A type of ear cancer

d)

A type of eye cancer

9.

What does metastasis mean?

a)
The spread of cancer cells from the original site to other parts of the body
b)
The elimination of cancer cells from the body
c)
The shrinking of cancer cells at the original site
d)
The development of cancer cells at the original site
10.

Which is cancer: benign or malignant?

a)
malignant
b)
benign
11.

Choose the possible contributions to the development of cancer by causing changes to a cell's genes.

a)
Exposure to radiation, certain chemicals, and viruses
b)
Eating a balanced diet
c)
Regular exercise
d)
Getting enough sleep
12.

Organize these options into the right categories

Categorize the following

divide in an organized manner

proliferate indefinitely

respond to signals appropriately

have a low mutation rate

undergo apoptosis when necessary

efficiently repair DNA damage

evade apoptosis

inefficient DNA repair

ignore signals for growth control

contain distinct features

lose specialized features

have the same shape

vary in size and shape

have one small nucleus

have large, variably shaped nuclei

arrange themselves in an organized manner

have disorganized arrangement

Healthy Cells
Cancer Cells
13.

What is an oncogene?

a)
A gene that prevents cancer
b)
A gene that has no effect on cancer
c)
A gene that cures cancer
d)
A gene that has the potential to cause cancer
14.

Are these cells normal or cancerous?​ (a)  

Choose from the below words
cancerous
normal