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WorksheetsPL-5 Adrenal Medulla and Stress Response
Total questions: 23
Worksheet time: 15mins
Which cells produced catecholamines in adrenal medulla.
Pinealocytes
Neural crest cells
Pituicytes
Which cells produces epinephrine?
Chromaffin cells with less dense granule
Chromaffin cells with very dense granule
Catecholamines are derived from this amino acids.
(a)
These two enzymes are involved in deactivation of catecholamines.
Monoamine oxidase (MAO)
Catechol-O-methyltranferase (COMT)
Phenylethanolamine-N-methyltransfersae
DOPA decarboxylase
Excretion forms of catecholamines are
Vanillyl mandelic acid (VMA)
DOMA
Metaneprhine and normetanephrine
Epinephrine and norepinephrine
Main effects of "Fight-or-Flight" response
Decreases mesenteric blood flow
Increases muscular blood flow
Increases rate of cellular metabolism
Decreases heart rate
How does catecholamines affect cellular metabolism?
Increases gluconeogenesis
Increases glycogenesis
Increases glycogenolysis
Increases lipolysis
Epinephrine secretion is increased when
Stress
Hypovolaemia
Hypoglycaemia
Hypertension
Action of catecholamines in adipose tissue.
Increase activity of HSL
Increases the activity of lipoprotein lipase
Promote lipogenesis
Promote mobilisation of fatty acids from liver to adipose tissue.
Actions of catecholamines in liver.
Increases gluconeogeensis and glycogenolysis
Inhibits glycogenesis
Promote uptake of glucose into liver
Promotes mobilisation of fatty acids in liver to adipose tissues
Which receptor does norepinephrine acts on?
Alpha receptors
Beta receptors
Both receptors equally
Which receptor does epinephrine acts?
Alpha receptors
Beta receptors
Both receptors equally
Increased heart rate is by
B1-adrenergic activity of epinephrine
B1-adrenergic activity of norepinephrine
A1-adrenergic activity of epinephrine
A1-adrenergic activity of nonepinephrine
Vasoconstriction is by
α1-adrenergic activity of norepinephrine
α1-adrenergic activity of epinephrine
β1-adrenergic activity of norepinephrine
β1-adrenergic activity of epinephrine
Lipolysis is caused by which receptor activity
β1
β2
α1
α2
β3
How does baroreceptor reflex helps in widening pulse pressure
Decreasing systolic blood pressure
Increasing diastolic blood pressure
Increasing systolic blood pressure
Decreasing diastolic blood pressure
How does norepinephrine leads to drop of total peripheral resistance?
Stimulation of
α1-receptors
Stimulation of β1-receptors on skeletal muscles and liver
Stimulation of
α2-receptors
Stimulation of β2-receptors on skeletal muscles and liver
Sympatho-adrenal system is best describe as
Production of catecholamines by adrenal glands enhances the sympathetic nervous system
Adrenal glands produces catecholamines to initiate stress response
Catecholamines produced under the influence of adrenal glands are used to initiate stress response
Metenkephalin is produced under the influence of which hormone?
Pro-enkephalin
ATP
Chromogranin A
Adrenomedullin
Dopamine induces which events?
Mesenteric vasodilation
Muscular vasoconstriction
Renal vasodilation
Positive inotrophic effect of heart
Which tumour involves in production of catecholamines?
Pheochromocytoma
Adrenocorticol adenoma
Paraganglioma
Adrenocorticol carcinoma
Cortisol affects cellular metabolism by
Reducing glucose utilisation
Increasing protein catabolism
Increasing fats degradation
Decreasing protein catabolism
Decreasing fat degradation
What are the other hormones produced during stress response?
Aldosterone and ADH
Endorphins
GH and glucagon
Insulin and somatostatin
