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DNA Replication & Its Enzymes

Total questions: 16

Worksheet time: 14mins

Name
Class
Date
1.

Imagine Benjamin and David are tiny scientists exploring the microscopic world of a cell! They notice that DNA replic​ation is happening. Can you tell them during which phase this occurs? .​ ​ (a)  

Choose from the below words
interphase

metaphase

telophase

anaphase

prophase

2.

Match the following

a)

Polymerase

1.

builds the complimentary DNA strand

b)

Ligase

2.

bonds DNA fragments together

c)

Primase

3.

Indicates whee DNA replication begins

d)

Helicase

4.

"unzips" the DNA

3.

Reorder the following

a)

DNA is unzipped

b)

Primase marks region to begin replication

c)

Polymerase builds complimentary DNA strand

d)

Ligase bonds DNA fragments

1)
2)
3)
4)
4.

Imagine Oliver and Ava are tiny scientists exploring a DNA molecule. After replication, each strand they observe has ​ (a)   new strand(s) and ​ (b)   old strand(s). Zoe, their friend, is curious to know the answer. Can you help them?

Choose from the below words

one

two

zero

5.

Aria, Lily, and Benjamin are studying DNA structures. They learned that each strand of the double helix serves as a (a)   for a new strand. Can you help them fill in the blank?

6.

Ethan, Ava, and William are in a science quiz competition. They got a tricky question, 'What is the principal enzyme involved in DNA replication?'

a)

glucose

b)

fructose

c)

DNA Polymerase

d)

Lactase

7.

Elijah, Aria, and Anika are in a science competition. They are shown a picture of an enzyme unwinding and unzipping DNA.

​They are asked to name this enzyme. Can you help them out?

a)

DNA Helicase

b)

DNA Ligase

c)

DNA polyermase

d)

RNA Polymerase

8.

Samuel, Elijah, and Aiden are on a mission to save the world from an alien invasion. The aliens' weakness is a specific DNA nucleotide pairing. Can you help them identify the correct DNA nucleotide pairings? (mark all that apply)

a)

Adenine with Thymine

b)

Guanine with Cytosine

c)

Thymine with Cytosine

d)

Adenine with Uracil.

e)

Uracil with Thymine

9.

Abigail, Zoe, and Mason are on a thrilling quest to decode a mysterious DNA strand they found in their science lab. The DNA strand reads 5'ATGCTCAGCTGA3'. Can you help them figure out the corresponding DNA strand?

a)

5'UACGAGUCGACU3'

b)

5'TACGAGTCGACT3'

c)

3'UACGAGUCGACU5'

d)

3'TACGAGTCGACT5'

10.

Imagine Michael, Benjamin, and Arjun are in a race to replicate a DNA strand. They have a toolbox of enzymes to help them. Can you help them put the enzymes in the correct order from start to finish?

a)

Helicase, DNA primase, DNA polymerase, Ligase

b)

RNA primase, Helicase, DNA polymerase, Ligase

c)

Helicase, RNA primase, DNA polymerase, Ligase

d)

DNA primase, Helicase, RNA polymerase, Ligase

11.

Imagine this, Mia and Benjamin are on a thrilling adventure inside a cell, exploring the structure of a DNA molecule.

They come across a type of bond (indicated by the arrows) that can easily be broken, allowing the two sides of DNA to move apart for use in the cell. Noah, their guide, asks them to identify this bond. What do you think it is?

a)

covalent bond

b)

peptide bond

c)

Nitrogen bond

d)

hydrogen bond

12.

Imagine Harper, Olivia, and Arjun are in a science lab, working on a DNA replication experiment. They come across a DNA template segment ACC GTA CTG ATC. Can you help them figure out which complementary strand this segment would produce during DNA replication?

a)

TGG CAT GAC TAG

b)

TCC GTA CTG ATC

c)

UGG CAU GAC UAG

d)

ACC GUA CUG AUG

13.

Maya, Evelyn, and Kai are in a heated debate about DNA replication in their biology class. Which of their descriptions is accurate?

a)

Maya says: 'the nucleotides of both strands of DNA are taken apart and used to assemble two completely new DNA molecules.'

b)

Evelyn says: 'the original double-stranded DNA is "unzipped" and each strand serves as a template for building a complementary DNA strand from free floating nucleotides.'

c)

Kai says: 'the original single stranded DNA is unzipped and is used to make a new DNA strand before being put back together.'

d)

Maya argues: 'the nucleotides of one strand of DNA are taken apart to form a new DNA molecules then its replaced by free nucleotides.'

14.

Put the steps of DNA replication in the correct order

a)

DNA unwinds

b)

Separate the double helix DNA - Helicase

c)

Add primer

d)

Elongation of the new DNA strand

e)

Ligation of DNA fragments

1)
2)
3)
4)
5)
15.

Imagine Liam, Ava, and Ethan are tiny scientists exploring the microscopic world of DNA replication. They come across two new DNA molecules. How would they identify these molecules?

a)

the molecule that Liam copied quickly

b)

each molecule has one strand that Ava calls "old" and one that Ethan calls "new"

c)

one molecule is entirely what Liam calls "old" and one is what Ava calls "new"

d)

the molecule that Ethan always copied with no mistakes

16.

Imagine Hannah, Aiden, and Abigail are tiny scientists exploring the microscopic world of DNA! Can you help them figure out which units are repeatedly joined together to form a strand of DNA?

a)

Amino Acids

b)

Nucleotides

c)

Fatty Acids

d)

Polysaccharides