Where do T cells develop?

T cells are involved in the ___ immune response.

Select all of the following that is true about T cells.

What are the two "lineages" of T cells?

Which of the two lineages make the majority of T cells?

The thymus and the proportion of T cells it produces increases with age.

Which of the following statements about the thymus is true?

Which of the following about the thymus is true?

Involution of the thymus

Early T cell precursor development occurs in the ___

Where do T cells go through selection and education processes?

Progenitor cells are not committed to the T lineage when they enter the thymus.

Immature T cells

Thymocytes that lack the TCR but beginning to rearrange their TCR genes

T cell development is driven by

Thymic cells that produce growth factors and ligands that contribute to T cell development.

Which receptor signaling commits the progenitor cell to the T lineage?

Growth factor that is secreted by thymic stromal cells

Notch +1 means the progenitor becomes a

Notch 1- means the progenitor becomes a

What are the screening processes for T cells?

If the TCR binds strongly to MHC class I or II molecules then ___

If the TCR binds with HIGH affinity to self antigen then the T cell ____

When does gene rearrangment occur to produce a functional TCR?

The first gene rearrangement in the double negative stage is of the ___ chain

When the beta chain is produced, is forms a complex with ___

Which rearrangement is first during the double negative stage?

Once the complete T cell receptor is formed then the cell expresses