Worksheets01/13/26 FM4 Mycology
Total questions: 5
Worksheet time: 10mins
A 50-year-old woman with uterine cancer has persistent fever despite being treated with broad-spectrum antibiotics. She has a PICC line that appears clean and dry. However, blood cultures are positive and show medium sized creamy colonies with a stellate appearance. A Gram stain shows large gram positive budding organisms of various sizes. Which of the following is the most likely causal organism?
Cryptococcus neoformans
Candida albicans
Histoplasma capsulatum
Coccidioides imitis
A 28-year-old woman returns to her primary care physician after being treated for a urinary tract infection. She now has vaginal itching and a thick, cheesy discharge. Microscopic examination of the discharge shows 5 neutrophils/hpf and many microorganisms likely to be the cause of the vaginitis. Which of the following best describes the microscopic appearance of the organism causing her discomfort?
Motile flagellated organisms
Long, slender bacilli single and in chains
Budding yeast with pseudohyphae
Epithelial cells covered by bacteria
A 35-year-old woman with allergic rhinitis managed by intranasal corticosteroids presents to the emergency room because of double vision and right eye pain. On physical exam, it is noted that her right eye is deviated laterally and bulging out of the socket. She also has headache, confusion and drowsiness. A CT scan of the head shows a large mass in the right frontal and ethmoidal sinuses, with destruction of bone and extension into the right orbit and right frontal lobe of the brain. She undergoes a surgical procedure to remove the infected tissue and broad aseptate ribbon-like hyphal structures with right angle branching are seen on frozen section. Which of the following is the most likely diagnosis?
Actinomycosis
Sporotrichosis
Aspergillosis
Zygomycosis
A 45-year-old woman pricked her thumb on a rose bush while gardening. Three weeks later, she developed a purple bump that started to get larger and ulcerate. She presented to the urgent care because the lesion began spreading to her 2nd finger and hand. A fungal culture is ordered and grows a fungus at 25C and yeast at 35C. Which of the following is the most likely causal organism?
Sporothrix schenckii
Candida albicans
Cryptococcus neoformans
Actinomyces israelii
A 21-year-old woman presents to her primary care physician with complaints of enlarging lymph nodes. She is noted to have a 2.0 cm axillary mass and several 1.0-1.5 cm neck masses bilaterally. She was raised in Fresno and is attending college in Los Angeles. A lymph node from the neck is excised and sent for surgical pathology examination. Samples are also sent for bacterial, fungal and AFB culture. A white mold grows on the sabaroud's dextrose agar plate at room temperature and a mold grows at 35C. Microscopic examination of the room temperature culture shows the presence of arthroconidia. Spherules are seen within the tissue on the H&E slide. Which of the following is the most likely causal organism?
Epidermophyton floccosum
Coccidioides immitis
Histoplasma capsulatum
Paracoccidioides brasiliensis
