WorksheetsNSAID/Anti-coagulant Adverse Side Effects
Total questions: 10
Worksheet time: 6mins
Which of the following is a common adverse side effect of both NSAIDs & anti-coagulants?
Stomach pain
Ulcer formation
Kidney problems
Increased bleeding risk
What is the correct MOA of anti-coagulants?
Thins the blood
Interferes with and delays the blood coagulation process
Stops blood from clotting
Dissolves the blood clot
What are two ways the long-term use of non-selective NSAIDs can increase your bleeding risk?
Reduced gastroprotection
Reduces the production of coagulation factors
Reduced platelet aggregation
Increases blood flow
What are the 2 targets of non-selective NSAIDs?
Arachidonic acid
Thromboxane A2
COX-1
COX-2
What is the target of selective NSAIDs?
Thromboxane A2
Arachidonic acid
COX-2
COX-1
Out of the following NSAIDs listed below what would you recommend to a patient taking anti-coagulants?
Etoricoxib
Ibuprofen
Naproxen
Diclofenac
Which enzyme promotes gastroprotection?
COX-1
COX-2
Amylase
Oxidases
What listed below is a prostaglandin that is important for platelet aggregation?
Arachidonic acid
COX-2
COX-1
Thromboxane A2
How does warfarin increase the risk of bleeding?
Inhibits enzyme vitamin K epoxide reductase and the downstream effects increases bleeding risk
Damages gastric mucosa
Binds to the active site of thrombin and the downstream effects increases the bleeding risk
Increases the formation of ulcers
Select as many relevant answers. What are the signs of excessive bleeding?
Passing blood in your stool
Sudden severe back pain
Vomiting blood
Difficulty breathing
