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14 - DNA and Replication (AP Bio)

Total questions: 29

Worksheet time: 16mins

Name
Class
Date
1.
Which of the following statements is TRUE regarding DNA replication?
a)
both sides of the DNA ladder are copied at the same time and at the same speed
b)
one of the original strands of DNA is conserved in the process
c)
the process occurs near the ribosomes in the cytoplasm of the cell
d)
the process is error-proof
2.
Which of the following is responsible for the creation of Okazaki fragments during replication?
a)
The two sides of the DNA ladder are not symmetrical
b)
Single strand binding proteins only attach to one side of the strand
c)
DNA helicase can only influence one side of DNA
d)
DNA polymerase can only travel in the 3’ to 5’ direction
3.
Which enzyme is responsible for unzipping (or unwinding) the DNA molecule?
a)
Helicase
b)
DNA polymerase
c)
Ligase
d)
DNA primase
4.
The arrow on the image indicates which end?
a)
3'
b)
5'
5.
Consider the base pair rule when answering this question. If a sample of DNA is 30% adenine, what % of the sample would you expect to be cytosine. (There is math involved here!)
a)
10
b)
20
c)
50
d)
70
6.
The photo taken by Rosalind Franklin provided what clue for Watson and Crick?
a)
the way bases paired
b)
the helix shape of the molecule
c)
the hydrogen bond locations
d)
the anti-parallel arrangement
7.
In the Hershey-Chase experiment, radioactive phosphorous was found in newly created phages. This supported which hypothesis?
a)
DNA was in the form of a double helix.
b)
DNA could be transformed into harmful variants.
c)
DNA was the molecule of heredity.
d)
DNA contained equal amount of thymine and adenine.
8.
Which of the following images most accurately illustrates DNA replication?
a)
A
b)
B
c)
C
d)
D
9.
Which type of mutation does not change an organism's phenotype despite changing it's genotype?
a)
missense
b)
nonsense
c)
silent
d)
frameshift
10.
Each time a cell divides, the telomeres:
a)
decrease in number
b)
decrease in size
c)
increase in number
d)
increase in size
11.
Which enzyme is responsible for binding Okazaki fragments?
a)
Helicase
b)
DNA polymerase
c)
Topoisomerase
d)
Ligase
12.

Consider one side of a strand of DNA. What is the complimentary strand's sequence? C A T G A A

(a)  

13.

What is the role of DNA polymerase during DNA replication?

a)

Binding Okazaki fragments

b)

Synthesizing new DNA strands

c)

Stabilizing the DNA helix

d)

Unzipping the DNA strands

14.

What is the function of topoisomerase in DNA replication?

a)

Initiating the replication process

b)

Preventing the DNA strands from tangling

c)

Adding nucleotides to the growing DNA strand

d)

Sealing gaps between Okazaki fragments

15.

Which enzyme is responsible for adding nucleotides to the growing DNA strand during replication?

a)

Helicase

b)

DNA polymerase

c)

Ligase

d)

Primase

16.

How does DNA polymerase ensure the accuracy of DNA replication?

a)

By unwinding the DNA double helix

b)

By synthesizing RNA primers

c)

By proofreading and correcting mismatched nucleotides

d)

By joining Okazaki fragments

17.

During DNA replication, the function of the RNA primer is to:

a)

Serve as a starting point for DNA synthesis

b)

Add nucleotides to the DNA strand

c)

Unwind the DNA helix

d)

Repair mistakes in DNA synthesis

18.

What is the main function of DNA polymerase during DNA replication?

a)

To break hydrogen bonds between nitrogenous bases

b)

To add nucleotides to the growing DNA strand

c)

To unwind the DNA double helix

d)

To join Okazaki fragments

19.

Which enzyme synthesizes RNA primers during DNA replication?

a)

DNA Ligase

b)

DNA Polymerase

c)

Primase

d)

DNA Helicase

20.

Which enzyme has the ability to proofread and correct errors during DNA replication?

a)

DNA Ligase

b)

DNA Helicase

c)

DNA Polymerase

d)

Primase

21.

Which enzyme is responsible for adding nucleotides to the growing DNA strand during replication?

a)

Helicase

b)

DNA polymerase

c)

Ligase

d)

Primase

22.

How does DNA polymerase ensure the accuracy of DNA replication?

a)

By unwinding the DNA double helix

b)

By synthesizing RNA primers

c)

By proofreading and correcting mismatched nucleotides

d)

By joining Okazaki fragments

23.

During DNA replication, the function of the RNA primer is to:

a)

Serve as a starting point for DNA synthesis

b)

Add nucleotides to the DNA strand

c)

Unwind the DNA helix

d)

Repair mistakes in DNA synthesis

24.

Click the rectangle that contains deoxyribose.

A
B
C
D
E
25.

Drag the labels to the appropriate place on the diagram.

a)Deoxyribose
b)Phosphate
c)A - T base pair
1
2
3
1)
2)
3)
26.

The two DNA strands are ​ (a)   ​ and form a​ ​ (b)  

Choose from the below words
antiparallel
double helix
parallel
perpendicular
single helix
triple helix
27.

Match the enzymes to the correct location.

a)

Helicase

b)

DNA Polymerase

c)

Ligase

1
2
3
1)
2)
3)
28.
Question Image

Match the following

a)

E

1.

primase

b)

G

2.

DNA polymerase

(on left side of image)

c)

H

3.

Okazaki fragment

d)

I

4.

DNA polymerase

(on right side of image)

e)

J

5.

ligase

29.

Which elements stabilize the DNA molecule during replication?

a)

helicase

b)

single strand binding proteins

c)

DNA polymerase

d)

trinucleotide repeats

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