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Vitamins INT MD

Total questions: 15

Worksheet time: 9mins

Name
Class
Date
1.

Biotin is involved in which of the following types of
reactions?

a)

Deaminations

b)

Hydroxylation

c)

Oxidation

d)

Reduction

e)

Carboxylation

2.

Which of the following vitamins is associated with
synthesis of coagulation factor prothrombin?

a)

Vitamin A

b)

Vitamin K

c)

Vitamin D

d)

Vitamin C

e)

Vitamin D

3.

To prevent rickets in case of chronic renal disorders, which
of the following substances should be administered?

a)

Cholecalciferol

b)

Ergocalciferol

c)

25-OH-calciferol

d)

1,25-di-OH-cholecalciferol

e)

High dietary magnesium

4.

Which of the following forms of vitamin A is used in the visual cycle:

a)

Retinol

b)

Retinoic acid

c)

Retinaldehyde

d)

Retinyl palmitate

e)

Retinyl acetate

5.

The disease pellagra is due to a deficiency of:

a)

Vitamin B6

b)

Nicotinic acid

c)

Pantothenic acid

d)

Folic acid

e)

Folic acid

6.

Which of the following coenzyme is involved in the
formation of hydorxy-proline during collagen synthesis?

a)

Pyridoxal-P

b)

TPP

c)

Cobalamine

d)

Biotin

e)

Ascorbic acid

7.

A hypochromic microcytic anaemia with increased Fe
stores in the bone marrow may be:

a)

Folic acid responsive

b)

Vitamin B12 responsive

c)

Pyridoxine responsive

d)

Vitamin C responsive

e)

Iron responsive

8.

In haemochromatosis, the liver is infiltrated with:

a)

Copper

b)

Iron

c)

Manganese

d)

Chromium

e)

Lipids

9.

Ceruloplasmin shows the activity of:

a)

ferroxidase

b)

reductase

c)

ligase

d)

transferase

e)

hydrolase

10.

In case of Wilson’s disease,
the features include all of the following, except:

a)

Kayser-Fleischer ring

b)

Low levels of caeruloplasmin

c)

Biliary excretion of Cu is decreased

d)

Progressive hepatic cirrhosis

e)

Urinary excretion of Cu is decreased

11.

A 75-year-old woman is seen in the emergency room with a fractured arm. Physical examination revealed multiple bruises and hemorrhages, periodontitis, and painful gums. Her diet consists predominately of weak coffee, bouillon, rolls, and plain pasta. Lab results indicated mild microcytic anemia. Which of the following enzymes should be less active than normal in this patient?

a)

Homocysteine methyltransferase

b)

γ-Glutamyl carboxylase

c)

Dihydrofolate reductase

d)

ALA synthase

e)

Prolyl hydroxylase

12.

One of the first chemotherapeutic agents was methotrexate, a compound that was effective in killing rapidly dividing cells like those of leukemias. This compound would be expected to elevate concentrations of which of the following compounds?

a)

Homocysteine and dUMP

b)

Thymine and choline

c)

Serine and methionine

d)

Glycine and methionine

e)

Homocysteine and thymine

13.

Which of the following components can be derived from tryptophan, along with its active compound?

a)

Biotin, carboxybiotin

b)

Intrinsic factor, cobalamin

c)

Pantothenic acid, coenzyme A

d)

Nicotinamide, nicotinamide adenine dinucleotide

e)

Pyridoxine, pyridoxal phosphate

14.

A 52-year-old female presents with fatigue of several months’ duration. Blood
studies reveal a macrocytic anemia, reduced levels of hemoglobin, elevated
levels of homocysteine. Which of the
following is most likely deficient in this patient?

a)

Folic acid and B12

b)

Vitamin B6

c)

Iron

d)

Vitamin C

e)

Cooper

15.

Which of the following statements describes the function of vitamin E in humans?

a)

It functions as a chain-breaking antioxidant.

b)

It functions to maintain the integrity of eyes.

c)

It promotes bone growth.

d)

It promotes clotting of blood.

e)

It serves as coenzyme in carboxylation reactions.