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DNA repl

Total questions: 12

Worksheet time: 8mins

Name
Class
Date
1.

In conservative DNA replication, each new DNA molecule contains one newly synthesized daughter strand and one paternal template strand of DNA.

a)

False

b)

True

2.

In DNA replication, only 1 strand is used as the template.

a)

False

b)

True

3.

DNA replication starts at special sites called origins of replication (Ori).

a)

False

b)

True

4.

DNA primase binds to DNA by complementary base pairing.

a)

False

b)

True

5.

RNA primers are required as DNA Polymerase requires a free 5’ OH group from pre-existing chain, to synthesis new DNA.

a)

False

b)

True

6.

DNA polymerase and DNA ligase help to catalyse the formation of phosphodiester bonds.

a)

False

b)

True

7.

Both leading and lagging strands are synthesised in the 5’ to 3’ direction.

a)

False

b)

True

8.

There is a need for multiple primers for the synthesis of lagging strand as the DNA molecule opens up gradually to expose new 3’ ends on the template (for lagging strand) in the replication fork.

a)

False

b)

True

9.

DNA ligase helps to remove RNA primers from the daughter strand.

a)

False

b)

True

10.

The failure of DNA polymerase I to replace the last primer removed with deoxyribonucleotides on the lagging strand results in a 3’ overhang, in eukaryotes.

a)

False

b)

True

11.

Which statements are correct for all nucleotides?

 

1      The nitrogen-containing base is always attached to carbon atom 1 of the pentose.

2      The phosphate group is always attached to carbon atom 5 of the pentose.

3      A condensation reaction occurs to join the nitrogen-containing base to the pentose.

4          Nucleotides are linked together by condensation reactions between phosphate groups.

a)

1, 2 and 3

b)

1 and 2 only

c)

1, 3 and 4

d)

2, 3 and 4

12.

How many phosphodiester bonds are present in a circular DNA molecule of 2700 base pairs?

a)

2699

b)

2700

c)

5398

d)

5400