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WorksheetsCell Injury - Pathology
Total questions: 10
Worksheet time: 4mins
What is the earliest morphologic manifestation of reversible cell injury?
Ribosomal detachment
Cellular swelling
Plasma membrane changes
Nuclear changes
Which of the following is a consequence of decreased ATP levels in reversible cell injury?
Increased protein synthesis
Activation of degradative enzymes
Decreased activity of Na+K+ Pump
Lysosomal rupture
What nuclear change is associated with reversible cell injury?
Pyknosis
Karyolysis
Chromatin clumping
Karyorrhexis
In irreversible cell injury, which enzyme's activation is associated with plasma membrane breakdown?
ATPase
Lipase
Caspase
None of the above
Which morphological change indicates irreversible cell injury?
Myelin figures
Ribosomal detachment
Mitochondrial dysfunction
Membrane blebbing
Which term describes nuclear fragmentation during irreversible cell injury?
Pyknosis
Karyorrhexis
Karyolysis
Chromatin clumping
What happens to lysosomes during irreversible cell injury?
They detach from the endoplasmic reticulum
They rupture, leading to autolysis
They swell but remain intact
They aggregate with mitochondria
Myelin figures are seen in?
Reversible cell injury
Irreversible cell injury
Niemann-Pick's cells
All of the above mentioned conditions
What is the consequence of increased mitochondrial permeability in irreversible cell injury?
Increased ATP production
Decreased electron transport chain activity
Ribosomal reattachment
Decreased cellular swelling
What kind of densities/inclusions in mitochondria indicate irreversible cell injury?
Chromatin clumps
Myelin figures
Amorphous densities
Ribosomal inclusions
