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Rabies and it's Prevention

Total questions: 40

Worksheet time: 12mins

Name
Class
Date
1.

What is the structure of the rabies virus?

a)

The rabies virus has a spherical structure and contains double-stranded DNA.

b)

The rabies virus has a cube-like structure and contains a segmented RNA genome.

c)

The rabies virus has a bullet-shaped structure, is enveloped, and contains a single-stranded RNA genome.

d)

The rabies virus is rod-shaped and lacks an envelope.

2.

How is rabies primarily transmitted to humans?

a)

Via consumption of undercooked meat from infected animals.

b)

Through bites from infected animals.

c)

By inhaling infected air particles.

d)

Through contact with contaminated water.

3.

What are the initial symptoms of rabies infection in human?

a)

Chest pain, shortness of breath, and fatigue.

b)

Nausea, vomiting, and diarrhea.

c)

Cough, sore throat, and runny nose.

d)

Fever, headache, and general weakness.

4.

How does the rabies virus enter the nervous system?

a)

The rabies virus enters via the respiratory system.

b)

The rabies virus enters through the skin.

c)

The rabies virus enters through the bloodstream.

d)

The rabies virus enters the nervous system via peripheral nerves.

5.

What are the late-stage symptoms of rabies?

a)

Skin rash, itching, pustules, ulcers, shock and death

b)

Cough, shortness of breath, runny nose, hypoxia, coma and death

c)

Nausea, vomiting, dysentery, spasticity, paralysis and death

d)

Confusion, agitation, hallucinations, paralysis, hydrophobia, coma, and death.

6.

What is the recommended schedule for Pre exposure rabies vaccination?

a)

2 doses for pre-exposure (0, 14 days)

b)

4 doses for pre-exposure (0, 7, 14, 21 days)

c)

3 doses for pre-exposure (0, 7, 21/28 days)

d)

3 doses for pre-exposure (0, 14, 28 days)

7.

What should be done immediately after a potential rabies exposure?

a)

Apply ice to the wound and wait for symptoms to appear.

b)

Wash the wound with soap and water and seek medical attention immediately.

c)

Take over-the-counter pain medication and monitor the wound.

d)

Ignore the wound and continue with daily activities.

8.

What is the incubation period for rabies in humans?

a)

3 to 5 days

b)

6 months to 1 year

c)

1 to 2 weeks

d)

1 to 3 months

9.

How does rabies affect the brain and nervous system?

a)

Rabies affects the brain and nervous system by causing inflammation, dysfunction, and severe neurological symptoms.

b)

Rabies only causes mild headaches and fatigue.

c)

Rabies enhances brain function and improves coordination.

d)

Rabies has no effect on the brain or nervous system.

10.

PEP (Post Exposure Prophylaxis) is the name for rabies treatment given to a person who has already been bitten and consists of the following:

a)

Only a course of rabies vaccination at the healthcare facility

b)

Only wound washing and disinfection.

c)

Wound washing and disinfection, a course of rabies vaccination, and sometimes RIG.

d)

Use anti inflammatory and anticholinergic drugs

11.

Children are more likely to be exposed to rabies because of the following reasons:

a)

They are less likely to report bites or scratches to their parents

b)

They do not recognize or avoid threatening behavior in dogs

c)

They are less capable of protecting themselves when they are attacked

d)

They are immunocompromised

12.

If a dog attacks you and you are on the ground, you should do the following.

a)

Pretend to be a rock

b)

Shout at the dog

c)

Try to attack the dog.

d)

Get up and run away from the dog.

13.

What can a vaccinator do to desensitize a vaccination site prior to injecting a dog?

a)

Rub the skin where the vaccine will be administered for 5 seconds.

b)

Desensitizing the site of vaccination is a waste of time.

c)

Pinch the dog to ensure that it won’t react to the injection.

d)

None of these

14.

Rabies vaccines should always be kept within a constant temperature range of:

a)

4 – 8 °C

b)

-4 - 0 °C

c)

room temperature

d)

10 – 15 °C

15.

The recommended dosage for RIG is as follows:

a)

HRIG: 40 IU/kg; ERIG: 40 IU/kg body mass of the patient

b)

HRIG: 20 IU/kg; ERIG: 40 IU/kg body mass of the patient

c)

HRIG: 20 IU/kg; ERIG: 20 IU/kg body mass of the patient

d)

HRIG: 40 IU/kg; ERIG: 20 IU/kg body mass of the patient

16.

What is the minimum WHO-recommended antibody titre for rabies to ensure adequate protection?

a)

15 IU/ml

b)

1 IU/ml

c)

0.2 IU/ml

d)

0.5 IU/ml

17.

How long is the observation period of a suspected rabid animal?

a)

7 days

b)

10 days

c)

21 days

d)

30 days

18.

Intramuscular rabies vaccines should be administered in the ______________ for all adults and children above the age of 2.

a)

Deltoid muscle

b)

Suprascapular muscle

c)

Gluteal region

d)

None of these

19.

Ante-mortem laboratory confirmation relies on the detection of viral RNA in the following recommended samples

a)

Cerebrospinal fluid

b)

Nasal Swab

c)

Saliva

d)

Urine & Feces

20.

Which of the following virus cause rabies

a)

Coronavirus

b)

Adenovirus

c)

Lyssa virus

d)

Ebola virus

21.

Which of the following is the confirmatory lesion of rabies

a)

Negri bodies

b)

Tiger heart

c)

Zebra stripes

d)

Synovitis

22.

Intramuscular rabies vaccines should be administered in the ______________ for infants and and children aged less than 2 years.

a)

Deltoid muscle

b)

Anterolateral thigh muscle

c)

Suprascapular region

d)

None of these

23.

What is the recommended schedule for Post exposure rabies vaccination?

a)

4 doses for Post exposure (0, 7, 21, 28 days)

b)

5 doses for Post exposure (0, 7, 14, 21, 28 days)

c)

5 doses for Post exposure (0, 3, 7, 14, 28 days)

d)

4 doses for Post exposure (0, 3, 7, 21 days)

24.

Which of the following symptoms is NOT associated with encephalitic rabies?

a)

Hydrophobia

b)

Rigidity of the axial jaw muscles

c)

Aerophobia

d)

Behavioural change

25.

What is the appropriate course of action when an immunocompromised patient has been exposed to a potentially rabid animals

a)

Only thorough wound washing should be applied in the case of immunocompromised individuals.

b)

Thorough wound washing and full course of rabies vaccine. RIG should not be provided to immunocompromised individuals.

c)

Thorough wound washing, a full course of rabies vaccine, and RIG (for category II and III exposures) administered directly into the wound.

d)

Thorough wound washing and RIG administered directly into the wound site. Rabies vaccine should not be provided to immunocompromised individuals.

26.

What often causes “blow-back” to occur?

a)

A syringe that is too big.

b)

A needle that is too small

c)

A needle that is not placed firmly on the syringe.

d)

None of these

27.

Which of the following country is free from rabies?

a)

China

b)

India

c)

Thailand

d)

Fiji

28.

According to WHO, how many deaths are caused by rabies worldwide each year?

a)

55,000 - 60,000 human deaths approximately

b)

80,000 - 90,000 human deaths approximately

c)

200,000 - 250,000 human deaths approximately

d)

15,000 - 30,000 human deaths approximately

29.

The time it takes for the rabies symptoms to appear is determined by the following:

a)

Where the bite is located on the person’s body

b)

How much rabies virus is deposited into the wound during the bite

c)

Immunity of the individual

d)

Type of the animal

30.

Who was the first person to be cured of rabies?

a)

Jeanna Giese

b)

Louis Pasteur

c)

Dr. Grancher

d)

Joseph Meister

31.

The first rabies vaccine was created by

a)

Joseph Lister

b)

Louis Pasteur

c)

Robert Koch

d)

Antoni van Leeuwenhoek

32.

What specific amino acid substitution in the rabies virus glycoprotein that confers resistance to neutralizing antibodies?

a)

Arginine-to-lysine a position 333

b)

Glutamic acid-to-aspartic acid at position 456

c)

Tyrosine-to-phenylalanine at position 272

d)

Asparagine-to-threonine at position 189

33.

Which of the following is the differential diagnosis for rabies in animals?

a)

Babesiosis

b)

Mycobacterium paratuberculosis

c)

Vestibular syndrome

d)

Listeriosis

34.

What is the function of rabies immunoglobulin (RIG) ?

a)

Rabies immunoglobulin prevents the onset of secondary infections.

b)

Rabies immunoglobulin enhances the patient’s antibody titres.

c)

Rabies immunoglobulin provides passive immunization by neutralizing RABV at the wound site.

d)

Rabies immunoglobulin enhance the wound healing

35.

What is the incubation period for fixed virus

a)

6-7 days

b)

10-14 days

c)

21-28 days

d)

60-90 days

36.

The intracytoplasmic inclusion bodies produce by rabies virus are

a)

Heinz bodies

b)

Negri bodies

c)

Councilman bodies

d)

Guarnieri bodies

37.

The test/procedure for the detection of rabies antigen is

a)

Histopathology

b)

Cytological smears

c)

Mouse inoculation test

d)

Immunoperoxidase test

38.

Which of the following is used to produce rabies vaccination

a)

Street virus

b)

Fixed virus

c)

Lab virus

d)

Intermittent virus

39.

Which of the following drug has been found to give good response against rabies virus in experimental animals.

a)

Phenobarbital

b)

Vincristine

c)

Remdesivir

d)

Clindamycin

40.

Sexual excitement is the remarkable symptom of rabies in

a)

Cat

b)

Cattle

c)

Sheep

d)

Pig