WorksheetsClostridioides difficile Infections Quiz
Total questions: 15
Worksheet time: 8mins
What is the etiological agent of Clostridioides difficile infections (CDI)?
Gram-negative, non-spore-forming bacillus
Gram-positive, spore-forming bacillus
Gram-negative, spore-forming bacillus
Gram-positive, non-spore-forming bacillus
What percentage of CDI cases are nosocomial?
10-20%
25-50%
66-75%
80-90%
Which of the following is a sign of CDI?
Constipation
Profuse, watery or mucoid green, foul diarrhea
Mild abdominal pain
Low fever
What is the role of antibiotics in CDI pathogenesis?
They prevent toxin production
They stimulate toxin production
They have no effect on toxin production
They eliminate toxin production
What is the typical leukocyte count in fulminant CDI?
<5,000/mm³
5,000-10,000/mm³
>15,000/mm³
10,000-15,000/mm³
What is the most sensitive method for diagnosing CDI?
Stool culture
Nucleic acid amplification test (NAAT)
Enzyme immunoassay
BD-GeneOhm™ C. difficile real-time PCR assay
What is the preferred treatment for an initial CDI episode according to the 2021 IDSA guidelines?
Vancomycin 125 mg PO QID for 10 days
Metronidazole 500 mg PO TID for 10-14 days
Fidaxomicin 200 mg PO BID for 10 days
Rifaximin 400 mg TID for 20 days
What is the recommended treatment for a first CDI recurrence?
Fidaxomicin 200 mg PO BID for 10 days
Vancomycin 125 mg PO QID for 10 days
Metronidazole 500 mg PO TID for 10-14 days
Rifaximin 400 mg TID for 20 days
What is a common side effect of metronidazole?
Bitter taste
Dysgeusia (bad taste)
High cost
Low efficacy
What is the availability of Bezlotoxumab in terms of dosage?
1000 mg/40 ml single use vial
500 mg/20 ml single use vial
2000 mg/80 ml single use vial
750 mg/30 ml single use vial
What is the effect of oral vancomycin on recurrent CDI according to the study?
No effect
Significantly lower incidence
Increased incidence
Unchanged incidence
What was the incidence of recurrent CDI in patients receiving placebo?
4.2%
10.5%
26.6%
15.8%
What is a limitation of the study on oral vancomycin for recurrent CDI?
Small sample size
Lack of determination of effect on intestinal flora
Short duration
High cost
What is the primary focus of environmental cleaning in CDI prevention?
Increase humidity
Identify and remove environmental sources
Add more plants
Use air fresheners
What type of study was conducted on oral vancomycin for recurrent CDI?
Prospective study
Retrospective study
Randomized controlled trial
Case study
