WorksheetsCNS Response to Injury Quiz
Total questions: 9
Worksheet time: 17mins
Identify the types of tissues and cells in the nervous system.
Describe the neuronal & axonal general response to injury.
Recognize the pathophysiological mechanisms of neural response to injury with special emphasis on the neuronal & glial reactions.
Recognize the role of microglia in CNS inflammation and repair.
Identify the cerebral edema as a possible outcome of various injurious agents.
What are the features of neuronal cell body injury?
Loss of Nissl substance (central chromatolysis)
Shrinkage of the cell body, pyknosis of the nucleus, disappearance of the nucleolus
Intense eosinophilia of the cytoplasm ('red neurons')
What are the types of irreversible cell injury?
Necrosis
Apoptosis
What are the types of intracellular inclusions?
Alzheimer's neurofibrillary tangle
Lewy bodies in Parkinsonism & dementia
Viral Inclusions
Lipofuscin pigment
What are the mechanisms of vasogenic edema?
Increased hydrostatic pressure inside vessel
Increased osmotic pressure in surrounding tissues
Decreased osmotic pressure inside vessel
