WorksheetsComplement Cascade Quiz
Total questions: 15
Worksheet time: 8mins
What is the initial complex formed in the complement cascade?
C1 complex
C3 convertase
C5b-9 complex
C3b and C3a fragments
Which pathway is involved in the formation of the C3 convertase?
Classical pathway
Alternative pathway
Both Classical and Alternative pathways
Neither pathway
What fragments are produced during C3 hydrolysis?
C3b and C3a fragments
C5a and C5b fragments
C2a and C4b fragments
C6 and C7 fragments
What does C3b cleave to form C5a and C5b?
C5
C3
C4
C2
Which components form the cylindrical membrane attack complex?
C5b, C6, C7, C8, and C9
C1, C2, C3, and C4
C3a, C3b, and C5a
C2a, C4b, and C3b
What happens to the cell at the end of the complement cascade?
It swells and bursts
It shrinks and dies
It divides
It becomes dormant
Which antibody is involved in the formation of the C1 complex?
IgG
IgA
IgM
IgE
What is the role of C3 convertase in the complement cascade?
It hydrolyzes C3
It forms the C1 complex
It cleaves C5
It forms the membrane attack complex
Which fragments are involved in the classical pathway?
C2a and C4b
C5a and C5b
C3b and C3a
C6 and C7
What is the function of the membrane attack complex?
To lyse the target cell
To bind antigens
To activate antibodies
To inhibit cell division
Which component directly cleaves C5 in the complement cascade?
C3b
C1 complex
C3 convertase
C5b-9 complex
What is the result of C3 hydrolysis in the complement cascade?
Formation of C3b and C3a fragments
Formation of C5a and C5b fragments
Formation of C2a and C4b fragments
Formation of C6 and C7 fragments
Which pathway can activate the complement cascade without antibodies?
Alternative pathway
Classical pathway
Both pathways
Neither pathway
What is the main function of the complement cascade?
To destroy pathogens
To produce antibodies
To activate T-cells
To inhibit immune response
Which fragment is responsible for cleaving C5?
C3b
C2a
C4b
C5a
