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Understanding Neurofibromatosis and Genetics

Total questions: 15

Worksheet time: 8mins

Name
Class
Date
1.

Which of the following is a type of Neurofibromatosis?

a)

Neurofibromatosis Type 3

b)

Neurofibromatosis Type 1

c)

Neurofibromatosis Type 4

d)

Neurofibromatosis Type 5

2.

What is a common symptom of Neurofibromatosis Type 1?

a)

Hearing loss

b)

Vision impairment

c)

Café-au-lait spots

d)

Muscle weakness

3.

Neurofibromatosis is primarily inherited in which pattern?

a)

Autosomal recessive

b)

X-linked dominant

c)

Autosomal dominant

d)

Mitochondrial

4.

Which diagnostic method is commonly used to confirm Neurofibromatosis?

a)

Blood test

b)

MRI scan

c)

Ultrasound

d)

X-ray

5.

Which of the following is NOT a symptom of Neurofibromatosis Type 2?

a)

Bilateral vestibular schwannomas

b)

Lisch nodules

c)

Hearing loss

d)

Balance problems

6.

What is the primary genetic cause of Neurofibromatosis Type 1?

a)

Mutation in the NF2 gene

b)

Mutation in the NF1 gene

c)

Deletion of chromosome 22

d)

Duplication of chromosome 17

7.

Which of the following is a characteristic feature of Neurofibromatosis Type 2?

a)

Neurofibromas

b)

Optic gliomas

c)

Vestibular schwannomas

d)

Café-au-lait spots

8.

How is Neurofibromatosis Type 1 typically diagnosed?

a)

Genetic testing

b)

Skin biopsy

c)

Blood pressure monitoring

d)

Bone density scan

9.

Which of the following is a potential complication of Neurofibromatosis Type 1?

a)

Diabetes

b)

Hypertension

c)

Scoliosis

d)

Asthma

10.

What is the likelihood of a child inheriting Neurofibromatosis if one parent has the condition?

a)

25%

b)

50%

c)

75%

d)

100%

11.

Which of the following is a common feature of Neurofibromatosis Type 1 in children?

a)

Cataracts

b)

Learning disabilities

c)

Heart defects

d)

Kidney stones

12.

What is the role of the NF1 gene in the body?

a)

Regulates blood sugar levels

b)

Controls cell growth

c)

Produces insulin

d)

Maintains bone density

13.

Which of the following is a diagnostic criterion for Neurofibromatosis Type 1?

a)

Presence of two or more neurofibromas

b)

Presence of a single café-au-lait spot

c)

Hearing loss

d)

Muscle atrophy

14.

What is the primary function of the NF2 gene?

a)

Regulates cholesterol levels

b)

Produces the protein merlin

c)

Synthesizes hemoglobin

d)

Controls blood pressure

15.

Which of the following is a common diagnostic tool for assessing tumors in Neurofibromatosis Type 2?

a)

CT scan

b)

EEG

c)

PET scan

d)

Audiometry