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Quiz #1: Nucleosides, Nucleotides and Nucleic Acids

Total questions: 49

Worksheet time: 25mins

Name
Class
Date
1.

  • Unbranched polymers composed 

 of repeating monomers called nucleotides

a)

Nucleosides

b)

Nucleotides

c)

Nucleic Acids

d)

Nucleoprotein

2.

  • Compose DNA and RNA consist of:
    a monosaccharide, a N-containing base, and a phosphate group

a)

Nucleosides

b)

Nucleotides

c)

Nucleic Acids

d)

Nucleoprotein

3.

  • Formed by joining the anomeric carbon of the monosaccharide with a N atom of the base.

a)

Nucleosides

b)

Nucleotides

c)

Nucleic Acids

d)

Nucleoprotein

4.

  • Formed by adding a phosphate group to the 5′-OH of a nucleoside.

a)

Nucleosides

b)

Nucleotides

c)

Nucleic Acids

d)

Nucleoprotein

5.

  • A polynucleotide contains a backbone consisting of alternating sugar and phosphate groups.

a)

Nucleosides

b)

Nucleotides

c)

Nucleic Acids

d)

Nucleoprotein

6.

Two main types of nucleic acids

a)

DNA and ATP

b)

DNA and RNA

c)

RNA and mRNA

d)

mRNA and tRNA

7.

What is the structure of DNA?

a)

B-form double helix

b)

A-form helix or linear

c)

Z-form single helix

d)

Triple-stranded helix

8.

What is the structure of RNA?

a)

B-form double helix

b)

A-form helix or linear

c)

Z-form single helix

d)

Triple-stranded helix

9.

Which of the following are functions of DNA? (Choose all that applies)

a)

Storage of genetic information (long term)

b)

Heredity: Transmission of genetic information to make other cells and new organisms

c)

Protein synthesis: Translates genetic information in DNA, transfer the genetic code from the nucleus to the ribosomes to make proteins

d)

Genetic Material in Some Viruses

10.

Which of the following are functions of RNA? (Choose all that applies)

a)

Storage of genetic information (long term)

b)

Heredity: Transmission of genetic information to make other cells and new organisms

c)

Protein synthesis: Translates genetic information in DNA, transfer the genetic code from the nucleus to the ribosomes to make proteins

d)

Genetic Material in Some Viruses

11.

DNA contains more nucleotides (several million) than RNA (a few thousand) due to its complex structure.

a)

True

b)

False

12.

Humans have how many chromosomes? How many pairs? (Numbers only)

(a)  

13.

Portion of the DNA molecule
responsible for the synthesis of a single protein?

(a)  

14.

In cells, what carries the DNA?

(a)  

15.

What carries genetic information?

(a)  

16.

In RNA, the monosaccharide is the?

a)

Aldopentose D-ribose

b)

Aldopentose D-2-deoxyribose

c)

Aldohexose D-ribose

d)

Aldohexose D-2-deoxyribose

17.

In DNA, the monosaccharide is the?

a)

Aldopentose D-ribose

b)

Aldopentose D-2-deoxyribose

c)

Aldohexose D-ribose

d)

Aldohexose D-2-deoxyribose

18.

Which of the N-containing bases are based on the structure of pyrimidine?

a)

Adenine

b)

Cytosine

c)

Guanine

d)

Uracil

e)

Thymine

19.

Which of the N-containing bases are based on the structure of purine?

a)

Adenine

b)

Cytosine

c)

Guanine

d)

Uracil

e)

Thymine

20.

DNA contains which of the following bases?

a)

Cytosine

b)

Adenine

c)

Thymine

d)

Guanine

e)

Uracil

21.

RNA contains which of the following bases?

a)

Cytosine

b)

Adenine

c)

Thymine

d)

Guanine

e)

Uracil

22.

To name a nucleoside derived from a pyrimidine base,

a)

use the suffix "-idine"

b)

use the suffix "-osine"

c)

add the prefix “deoxy-“

23.

For deoxyribonucleosides,

a)

use the suffix "-idine"

b)

use the suffix "-osine"

c)

add the prefix “deoxy-“

24.

To name a nucleoside derived from a purine base,

a)

use the suffix "-idine"

b)

use the suffix "-osine"

c)

add the prefix “deoxy-“

25.

Name the product: D-ribose + cytosine

a)

Cytidine, a ribonucleoside

b)

Cytidine, a ribonucleotide

c)

deoxycytidine, a ribonucleoside

d)

deoxycytidine, a ribonucleotide

26.

Name the ribonucleoside: D-2-deoxyribose + adenine

(a)  

27.

The identity and order of the phosphates distinguish one polynucleotide from another (primary structure)

a)

True

b)

False

28.

In DNA, the sequence of the bases carries the __________ of the organism.

a)

Gene

b)

Genetic Information

c)

Chromosome

29.

A polynucleotide has one free phosphate group
at the #’ end and one free OH group at the #’ end.

(a)  

30.

Who initially proposed the DNA model?

a)

Rosalind Franklin and Maurice Wilkins

b)

James Watson and Francis Crick

c)

Erwin Chargaff and Linus Pauling

d)

Charles Darwin and Gregor Mendel

31.

In what year was the DNA model proposed by Watson and Crick?

a)

1945

b)

1961

c)

1953

d)

1955

32.

Who confirmed the DNA model of Watson and Crick?

a)

Linus Pauling

b)

Erwin Chargaff

c)

Rosalind Franklin

d)

Martha Chase

33.

In nucleotides, the phosphate group and nucleoside are joined by what bond?

a)

N-glycoside

b)

H-bond

c)

Phosphodiester bond

d)

Phosphodiester linkage

34.

In nucleosides, the base and monosaccharide are joined by what bond?

a)

N-glycoside

b)

H-bond

c)

Phosphodiester bond

d)

Phosphodiester linkage

35.

Nucleic acids (DNA and RNA) are polymers of nucleotides joined by what bond?

a)

N-glycoside

b)

H-bond

c)

Phosphodiester bond

d)

Phosphodiester linkage

36.

Base pairs are joined by what bond?

a)

N-glycoside

b)

H-bond

c)

Phosphodiester bond

d)

Phosphodiester linkage

37.

The two strands of DNA run in what orientation?

a)

Convergent

b)

Perpendicular

c)

Parallel (same direction)

d)

Antiparallel (opposite direction)

38.

DNA consists of two polynucleotide strands that wind into which type of helix?

a)

Left-handed double helix

b)

Right-handed double helix

c)

Left-handed single helix

d)

Right-handed triple helix

39.

In the structure of DNA, where are the sugar-phosphate groups and the nitrogenous bases located?

a)

Sugar-phosphate groups lie on the inside, and bases lie on the outside.

b)

Sugar-phosphate groups lie on the outside, and bases lie on the inside.

c)

Both sugar-phosphate groups and bases are on the outside.

d)

Both sugar-phosphate groups and bases are on the inside.

40.

Which best describes base pairing?

a)

Purines and pyrimidines pair randomly with each other.

b)

A pyrimidine can pair with either a purine or pyrimidine.

c)

A pyrimidine can only pair with a purine.

d)

Only purines can form hydrogen bonds with each other.

41.

Which of the following is the correct base pairing for DNA?

a)

A-U (2 H-bonds)

C-G (3 H-bonds)

b)

A-T (2 H-bonds)

C-G (3 H-bonds)

c)

A-T (3 H-bonds)

C-G (2 H-bonds)

d)

A-U (3 H-bonds)

C-G (2 H-bonds)

42.

Which of the following is the correct base pairing for RNA?

a)

A-U (2 H-bonds)

C-G (3 H-bonds)

b)

A-T (2 H-bonds)

C-G (3 H-bonds)

c)

A-T (3 H-bonds)

C-G (2 H-bonds)

d)

A-U (3 H-bonds)

C-G (2 H-bonds)

43.

Which of the following is the most stable base pair?

a)

A-T

b)

C-G

c)

A-U

d)

T-U

44.

Select all the base pairs that are susceptible to mutagen:

a)

A-T

b)

A-U

c)

C-G

d)

T-A

e)

G-C

45.

In nucleotide formation, what is phosphorylation?

a)

Removal of water to add a phosphate group to a sugar or existing phosphate group

b)

Addition of a hydroxyl group to a sugar

c)

Removal of a phosphate group from a molecule

46.

What happens if AMP (adenosine 5'-monophosphate) is phosphorylated?

a)

It becomes ADP (adenosine diphosphate) and then can be further phosphorylated to form ATP (adenosine triphosphate).

b)

It breaks down into adenosine and phosphate ions.

c)

It becomes cAMP (cyclic adenosine monophosphate) immediately.

d)

It forms only ATP directly without any intermediate.

47.

Which of the following is correct? (Choose all that apples)

a)

Enzyme: Nucleoprotease
Nucleoprotein > Nucleic acids + histones

b)

Enzyme: Nuclease
Nucleic acids > Nucleotides

c)

Enzyme: Nucleotidase
Nucleotides > Nucleosides

d)

Enzyme: Nucleosidase
Nucleosides > base + sugar

e)

Enzyme: Nucleicase
Nucleic acids > Nucleotides

48.

What do you call the process of breaking down proteins from nucleoproteins to the simplest form of base and sugar?

a)

Hydrolysis

b)

Phosphorylation

c)

Deamination

d)

Denaturation

49.

Which of the following is a conjugated protein?

a)

Nucleoprotein

b)

Nucleic acids

c)

Nucleotides

d)

Nucleosides

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