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WorksheetsReading Signal Transduction Pathways
Total questions: 5
Worksheet time: 8mins
Examine the Signal Transduction pathway below and put the events in the correct order.
Ligand binds to the receptor
Relay Protein 1 is activated
Relay Protein 2 is activated
Response occurs in the cell.
Examine the Signal Transduction pathway and put the events in the correct order.
Ligand binds to the receptor
adenylyl cyclase converts ATP into cAMP, removing two phosphates and linking the remaining phosphate to the sugar in a ring shape.
cAMP activates an enzyme called protein kinase A (PKA)
Response occurs in the cell.
Examine the Signal Transduction pathway and put the events in the correct order.
Ligand binds to the receptor
an enzyme called phospholipase C cleaves (chops) PIP2 into two fragments, DAG and IP3
DAG stays in the plasma membrane and activates a target called protein kinase C (PKC)
Phosphorylation occurs
Response occurs in the cell.
Examine the Signal Transduction pathway and put the events in the correct order.
Ligand binds to the receptor
an enzyme called phospholipase C cleaves (chops) PIP2 into two fragments, DAG and IP3
IP3 - diffuses into the cytoplasm and can bind to ligand-gated calcium channels in the endoplasmic reticulum
Ca2+ is released and binds to proteins
Response occurs in the cell.
Examine the Signal Transduction pathway and put the events in the correct order.
Ligand (growth factor) binds to the EGF receptor
activated receptors trigger a series of events that activate the kinase Raf.
Active Raf phosphorylates and activates MEK, which phosphorylates and activates the ERKs.
ERKs phosphorylate and activate a variety of target molecules.
Response occurs in the cell.
