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Worksheets

Mutations

Total questions: 20

Worksheet time: 16mins

Name
Class
Date
1.

A change in a gene, group of genes or chromosome that results in a change in the proteins

a)

Replication

b)

Mutations

c)

Translation

d)

Transcription

2.

A permanent change in the DNA sequence

which can affect a single gene or group of genes

a)

Homeostasis

b)

Somatic Cell

c)

Chromosomal Mutation

d)

Gene Mutation

3.

One nucleotide base is changed so only one amino acid

is affected

a)

Substitution Mutation

b)

Point Mutation

c)

Translocation

d)

Inverse Mutation

4.

A point mutation where one nucleotide base replaces an original nucleotide base

a)

Inversion Mutation

b)

Chromosomal Mutation

c)

Translocation

d)

Substitution Mutation

5.

A substitution mutation that has no effect

on amino acids sequence

a)

Insertion Mutation

b)

Translocation

c)

Silent Mutation

d)

Deletion Mutation

6.

A nucleotide base is inserted or deleted shifting the entire DNA sequence. Entire protein will be changed.

a)

Substitution Mutation

b)

Silent Mutation

c)

Frameshift Mutation

d)

Translocation

7.

A frameshift mutation where a nucleotide base

is removed from the DNA sequence.

a)

Deletion Mutation

b)

Substitution Mutation

c)

Translocation

d)

Silent Mutation

8.

Mutations that involve parts of or all of

a chromosome

a)

Replication

b)

Deletion Mutation

c)

Chromosomal Mutation

d)

Transcription

9.

Part of a chromosome

is deleted

a)

Deletion Mutation-Gene

b)

Translocation

c)

Deletion Mutation -Chromosomal

d)

Crossing Over

10.

Part of a chromosome is repeated

a)

Gene Mutation

b)

Point Mutation

c)

Deletion Mutation

d)

Duplication Mutation

11.

Part of a chromosome is reversed.

a)

Inversion Mutation

b)

Deletion Mutation

c)

Translocation

d)

Point Mutation

12.

Part of one chromosome is transported and attached

to a non-homologous chromosome

a)

Inversion Mutation

b)

Translocation Mutation

c)

Duplication Mutation

d)

Point Mutation

13.

Failure of homologous chromosomes

to separate during meiosis.

Results in gametes with either one extra or one missing chromosome.

a)

Translocation

b)

Nondisjunction

c)

Replication

d)

Transcription

14.

Condition caused by nondisjunction at pair 21 during meiosis.

Individuals have an extra chromosome

at pair 21, or a total of 47 chromosomes.

Also called Trisomy 21.

a)

Cystic Fibrosis

b)

Translocation

c)

Hemophilia

d)

Down Syndrome

15.
What is a Gene?
a)
A segment of RNA that encodes for a protein
b)
A chromosome
c)
A segment of DNA that encodes for a protein
d)
Your genome
16.

DNA molecule segment is : TTA CGC AAG
The mutated DNA segment is TTC GCA AG. This is an example of ___ mutation.

a)

Missense Substitution

b)

Deletion Frameshift

c)

Insertion Frameshift

d)

Nonsense Substitution

17.

What type of chromosomal mutation is this?

a)

Translocation

b)

Inversion

c)

Deletion

d)

Duplication

18.

ATT TGA GCC- Original
ATT GAG CC - Mutated
The example above is an example of a 

a)

Insertion- Frameshift

b)

Deletion- Substitution

c)

Deletion -Frameshift

d)

Missense-Substitution

19.

Any change in the sequence of DNA is...

a)

Genetic Variation

b)

Transformation

c)

Meiosis

d)

Mutation

20.

Genetic mutations can be...

a)

beneficial, harmful, or neutral

b)

beneficial only

c)

harmful only

d)

neutral only