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Suli Event

Total questions: 4

Worksheet time: 2mins

Name
Class
Date
1.

Activation of osteoblasts by molecules secreted from stromal cells, and from the myeloma cells themselves, causes bone destruction that leads to multiple well-defined osteolytic lesions, and radiological changes resembling those of generalized osteoporosis and hypercalcaemia

a)

True

b)

False

2.

In 50% of patients with myeloma, the paraprotein is IgA, in 25% it is IgG, in 20% it is light chain only, and in 1–2% it is IgD or IgE. IgM-producing myelomas are extremely rare.

a)

True

b)

False

3.

Venetoclax is approved for use in multiple myeloma and has single-agent activity specifically in patients with t(11;14) subtype of multiple myeloma.

a)

True

b)

False

4.

ØIsatuximab targets a specific epitope on CD38 different from the binding site for daratumumab?

a)

True

b)

False