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breast lump and nipple discharge

Total questions: 20

Worksheet time: 10mins

Name
Class
Date
1.

A 63 year old lady presents with nipple erythema and ulceration. A nipple biopsy reveals large round cells with large nuclei, prominent nucleoli and abundant vacuolated cytoplasm within the epidermis. The cells are positive for CK7 and negative for S100. What is the most likely diagnosis?

a)

malignant melanoma

b)

Phylloides tumor

c)

Paget's disease of the breast

d)

Bowen's disease

2.

•A 50-year-old post menopausal single woman on regular HRT for her menopausal symptoms, has a right mastectomy following mammographic discovery of a carcinoma of the right breast. She had history of breast lump since 23 years old but she ignore it. Which of the following is a well-known characteristic or association of breast cancer?

a)

nulliparous

b)

hormonal medication

c)

past history of breast lump

d)

advance age

3.

•A 20-year-old woman presents with a solitary discrete, freely movable, firm, rubbery, nontender, well-circumscribed breast lesion. The most likely diagnosis is?

a)

atypical intraductal papiloma

b)

fibrocystic disease

c)

lipoma of the breast

d)

ductal ectasia

4.

A breast lump (mass) is a thickening or bump that feels different from surrounding breast tissue. Which of the following statements about breast lumps is NOT correct?

a)

all breast lump is a cancerous lesion

b)

all breast lump must investigated

c)

all breast lump is a solid or fluid filled mass

d)

breast lump can happen in male

5.

•A 57-year-old woman presents with painfull left lump for the past 3 months . On examination, the left breast is markedly erythematous,swollen, and warm to touch. Left breast lump is 5x4 cm in size fix to the skin and muscle. There is also significant dimpling of the breast (peau d’orange). In addition, the left nipple is completely retracted and associated with pus discharge. TRU-CUT biopsy shows invasive ductal carcinoma . Which of the following is the likely diagnosis?

a)

Inflammatory breast carcinoma

b)

Advance breast carcinoma

c)

infected breast carcinoma

d)

breast carcinoma with mastitis

6.

     An 18-year-old student presents with a 6-month history of a painless lump in her right breast. She is currently in mid cycle of menstruation and does not report any change in the lump. On examination a 3 cm x 2 cm lump is found in the inner lower quadrant of the right breast. Excisional biopsy revealed fibroadenoma.

What is the MOST supporting feature for above diagnosis during physical examination?

a)

Firm in consistency

b)

Freely mobile

c)

Single swelling

d)

smooth surface

7.

A breast feeding mother presented to casualty with 5 days history of left breast mass which is painful. On examination she was noted to have a tender 3x3cm breast lump with surrounding erythema and cracked nipple. What is the most likely diagnosis?

a)

granulomatous mastitis

b)

infected breast lump

c)

cutaneous breast abscess

d)

inflammatory breast cancer

8.

a 37 years-old nulliparous women, presented with mulitple episode of breast pain and swelling since two years. She noticed everytime the breast lump occur, she have to consume antibiotic and the lump resolves temporarily. No risk of cancer, no family history of breast lesion. What do you think the most likely diagnosis ?

a)

Inflammatory breast cancer

b)

infected breast lump

c)

Granulomatous mastitis

d)

breast asbcess

9.

a 3 years-old girl complaints to her mother about the swelling on her right breast since a week. However the swelling is non-tender and no discharge. Otherwise the girl is active and no other complain. What is your diagnosis ?

a)

gynaecomastia

b)

fibroadenoma

c)

early thelarche

d)

advance puberty

10.

a 47 years-old-lady, presented to surgical outpatient department with the symptoms of painless right breast lump for the 3 months. She had no constitual symptoms. The lump is about 3x4cm upper outer quadrant, mobile and non tender. A percutaneous, ultrasound-guided core needle biopsy of the ovoid mass within the right breast was consistent with a grade I (low-grade) follicular B-cell lymphoma. What is the best treatment for her ?

a)

mastectomy first before chemotheraphy

b)

radiotherapy first before chemotherapy

c)

chemothearpy first before mastectomy

d)

mastectomy first before radiotheraphy

11.

A 32-year-old female comes to the surgical clinic complaining of painless right breast lump for the past 2 months. On examination noted to have skin dimpling above the lump. The surgeon decided to do breast conversing surgery on her.

What is the MOST IMPORTANT history to support your diagnosis ?

a)

History of nipple discharge

b)

Itchiness area around the nipple areola complex

c)

Past history of breast surgery

d)

Family history of breast cancer

12.

A 28-year-old woman presents to casualty complaining of left breast pain and

           redness with a recently enlarging swelling next to the nipple. She has been breast-

           feeding her newborn baby. On examination, she has low grade fever and there is a

           tense peri-areolar swelling in the upper outer quadrant of the right breast.

           What is the most likely diagnosis?

a)

infected breast cyst

b)

Granulomatous mastitis

c)

Breast abscess

d)

Periductal Mastitis

13.

WHICH OF THIS STATEMENT IS CORRECT ABOUT THE STAGING OF BREATS CANCER

a)

T1 (includes T1a, T1b, and T1c): Tumor is 1.9 cm (3/4 of an inch) or less across.

b)

N2: Cancer has spread to 4 to 9 lymph nodes under the arm, or cancer has enlarged the internal mammary lymph nodes

c)

T2: Tumor is more than 2.1 cm but not more than 4.9 cm (2 inches) across

d)

T0: Pimary tumor can not be accessed.

14.

What is the best Imaging modality to diagnosed breast cancer in the patient with post radical mastectomy and reconstruction of breast surgery using Latismus flap which presenting to the surgical clinic with breast lump at the previous scar ?

a)

CT scan

b)

PET Scan

c)

MRI breast

d)

USG breast

15.

A 48-year-old woman presents with a hard, irregularly shaped lump in her left breast that has been present for 3 months. The lump is fixed to the surrounding tissue, and there are no palpable lymph nodes. What is the most suspicious feature of this lesion, and what is the next appropriate step in its management?

a)

The lump is painless; biopsy is not needed

b)

The lump is mobile; a benign process is likely

c)

The lump is hard and fixed; proceed with a core needle biopsy.

d)

The lump is a cyst; aspiration is the best initial step.

16.

52 years old malay ladies, presented with painless left breast lump for the past three months. On further questioning she had implanted a silicone breast on the left side 5 years ago. Which of the imaging modality is the best for her ?

a)

Left breast MRI

b)

Left breast CT scan

c)

Left breast usg

d)

Left breast xray

17.

A 55-year-old woman presents with a 6 cm breast mass with skin dimpling and fixed axillary lymph nodes. Biopsy confirms triple-negative breast cancer. CT scan shows no distant metastasis.

What is the MOST APPROPRIATE initial management?

a)

Simple Mastectomy then followed by radiotherapy to axilla

b)

Start radiotherapy first then chemotherapy

c)

Neoadjuvant chemotherapy

d)

Start hormonal therapy

18.

A 42-year-old woman is diagnosed with ductal carcinoma in situ (DCIS) confined to one quadrant of the breast. There is no invasive component.

What is the MOST APPROPRIATE treatment?

a)

Adjuvant chemotherapy

b)

Wide local excision with radiotherapy

c)

Simple mastectomy with axillary clearance

d)

Start Hormonal therapy first

19.

A 50-year-old woman undergoes wide local excision and sentinel lymph node biopsy for early breast cancer. One sentinel node is positive for metastasis.

What is the MOST APPROPRIATE next step?

a)

Completion axillary lymph node dissection

b)

Start chemotherapy without further surgery

c)

Completion of mastectomy

d)

radiotherapy of axilla

20.

A 45-year-old woman is diagnosed with HER2-positive invasive breast cancer with lymph node involvement. She has completed surgery.

Which adjuvant treatment is MOST APPROPRIATE?

a)

oral Tamoxifen with radiotherapy

b)

25 Rads of Radiotherapy

c)

Trastuzumab with chemotherapy

d)

Trastuzumab with tamoxifen