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Senyawa dari Sponge Laut

Total questions: 22

Worksheet time: 11mins

Name
Class
Date
1.

What is the name of the compound that has antibiotic activity?

a)

Halichondrin B

b)

Spirohexenol

c)

Aeroplysinin

d)

Okadaic acid

e)

Halitoxin

2.

What is the name of the compound that is usually found in marine sponges with potential as an anti-cancer agent?

a)

Spongein A

b)

Marinotoxin

c)

Coralene

d)

Spongestatin

e)

Oceanolide

3.

What is the anti-inflammatory compound that can be found in marine sponges?

a)

Pseudopterosin

b)

Discodermolide

c)

Latrunculin

d)

Dysidamin

e)

Theonellamide A

4.

What is the name of the compound known as an anti-tumor agent derived from sponges?

a)

Latrunculin

b)

Discodermolide

c)

Spongistatin

d)

Dysideamine

e)

Petrosin

5.

What is the main function of Spongein A, found in marine sponges?

a)

Antifungal

b)

Antioxidant

c)

Anti-cancer

d)

Antiviral

e)

Antibiotic

6.

What is the compound that can be found in marine sponges with potential as an HIV enzyme inhibitor?

a)

Manzamine A

b)

Okadaic acid

c)

Latrunculin

d)

Ptilomycalin A

e)

Discodermolide

7.

The compound from marine sponges known to have antiviral properties is...

a)

Theonellamide A

b)

Spongestatin

c)

Aeroplysinin

d)

Halichondrin B

e)

Petrosin

8.

What is the compound that can be found in marine sponges with potential as an inhibitor of cancer cell growth?

a)

Halitoxin

b)

Discodermolide

c)

Latrunculin

d)

Spongestatin

e)

Marinotoxin

9.

Why are marine sponges often used for isolating compounds?

a)

Rich in nutrients

b)

Easy to process

c)

Contains unique compounds

d)

No chemical content

e)

Resistant to weather changes

10.

How is the isolation process of compounds from marine sponges carried out?

a)

By drying the sponge under sunlight

b)

Heating the sponge at high temperatures

c)

Extracting compounds using special solvents

d)

Feeding additional food to the sponge

e)

Using genetic isolation technology

11.

What is the main benefit of using compounds isolated from marine sponges?

a)

Increase sponge resistance to predators

b)

Development of new drugs

c)

Enhance color and beauty of sponges

d)

Reduce the number of sponges in water

e)

Accelerate sponge growth

12.

What can be a challenge in using marine sponges for compound isolation?

a)

Low sponge species diversity

b)

Limited availability in water

c)

Difficulty in extracting compounds

d)

No health benefits

e)

Not environmentally friendly

13.

What is the main role of marine sponges in pharmacology?

a)

Become a drug

b)
c)
d)
e)
14.

What is the main function of marine sponges in pharmacology?

a)

To become approved drugs

b)

To produce hundreds of compounds with interesting pharmacological activity

c)

To function as filter feeders

d)

To produce only secondary metabolites

e)

Only to withstand certain marine environments

15.

What results from the chemical diversity of sponges?

a)

Nucleosides

b)

Terpenes

c)

Sterols

d)

Cyclic peptides

e)

All answers are correct

16.

Why do sponges produce various chemical compounds?

a)

To dissolve in water

b)

As a defense against predators or competition for space

c)

So they can move quickly

d)

Only to attract attention

e)

Unclear according to the text

17.

What makes the Mediterranean Sea considered a biodiversity hotspot?

a)

High diversity and endemism

b)

Very hot climate

c)

Few species originating from the Atlantic Ocean

d)

Lack of natural resources

e)

Low diversity

18.

What is the composition of the skeleton of sponges in the class Hexactinellida?

a)

Calcium carbonate (CaCO3)

b)

Silicon dioxide (SiO2)

c)

Organic collagen network

d)

Spongin

e)

All answers are incorrect

19.

What is the main function of the molecules produced by marine sponges, especially from Demospongiae, such as spongosine, spongouridine, and spongothymidine?

a)

To become cellular building blocks

b)

To enhance parasite growth

c)

To protect against diseases, predators, and parasites

d)

To promote nucleic acid polymerization

e)

To accelerate cell division

20.

Why is Avarone considered more effective in inhibiting tumor growth compared to Avarol?

a)

More toxic to cancer cells

b)

Induces apoptosis through the PERK–eIF2α–CHOP pathway

c)

More selective against leukemia cells

d)

Has stronger cytostatic effects

e)

Inhibits Patched efflux activity in melanoma cells

21.

Why are natural sources, including Mediterranean sponges, considered to provide new ideas for pharmaceutical development related to neurological diseases?

a)

Irregular biochemical pathways

b)

Complex medical approaches

c)

Current pharmacotherapy is unsatisfactory

d)

All answers are correct

e)

Certain diseases

22.

What effect does Spongia officinalis have on seizures and pain sensations in mice?

a)

Increases seizures

b)

Reduces seizures

c)

Increases pain sensations

d)

No effect

e)

Causes pain sensations