wayground logo

Free Printable Worksheets

NEW

Font size

S
M
L
XL
Worksheets

Mediator of Inflammation

Total questions: 15

Worksheet time: 12mins

Name
Class
Date
1.

Which of the following is a property of mediators of inflammation?

a)

Produced locally by cells at the site of inflammation

b)

Derived from active precursors

c)

Long-lived

d)

Cannot stimulate other mediators.

2.

Fill in the blank: _______ are newly synthesized mediators from all leukocytes, platelets, and EC.

a)

Prostaglandins

b)

Serotonin

c)

Lysosomal enzymes

d)

Histamine

3.

Which mediator is sourced from mast cells, basophils, and platelets?

a)

Serotonin

b)

Nitric oxide

c)

Histamine

d)

Cytokines

4.

Fill in the blank: _______ are mediators that cause the dilation of blood vessels and increase the permeability of capillaries.

a)

A) Kinins

b)

B) Prostaglandins

c)

C) Cytokines

d)

D) Chemokines

5.

Fill in the blank: _______ are mediators that are involved in the regulation of immune responses and inflammation.

a)

Cytokines

b)

Histamine

c)

Prostaglandins

d)

Chemokines

6.

Which of the following mediators is involved in the process of vasodilation and increased vascular permeability?

a)

Kinins

b)

Leukotrienes

c)

Complement

d)

Cytokines

7.

Histamine is associated with which of the following actions?

a)

Endothelial activation

b)

Muscle relaxation

c)

Neuronal inhibition

d)

Bone growth

8.

Leukotrienes are produced in leukocytes and _______ cells.

a)

mast

b)

red blood

c)

nerve

d)

muscle

9.

Leukotrienes are involved in _______ and smooth muscle reactions.

a)

leukocyte recruitment

b)

protein synthesis

c)

DNA replication

d)

cell division

10.

Which cytokine is primarily sourced from macrophages and other cells and is involved in systemic effects?

a)

IL-6

b)

IL-1

c)

TNF

d)

IL-17

11.

Kinins are derived from plasma proteins by the action of specific proteases called ______.

a)

Kallikreins

b)

Kininogens

c)

Enzymes

d)

Hormones

12.

Fill in the blank: The activation of plasminogen to plasmin is part of the _______ system.

a)

Kinin

b)

Clotting

c)

Fibrinolytic

d)

Complement

13.

Which action is associated with leukotrienes C4, D4, E4?

a)

A) Vasodilation

b)

B) Vasoconstriction

c)

C) Increased vascular permeability

d)

D) Chemotaxis, leukocyte adhesion.

14.

What is the effect of Prostaglandin E2 (PGE2) on blood vessels?

a)

Causes vasoconstriction

b)

Causes vasodilation

c)

Inhibits platelet aggregation

d)

Promotes inflammation

15.

Which mediator is known for its role in chemotaxis of leukocytes?

a)

Histamine

b)

Leukotrienes

c)

Cytokines

d)

Prostaglandins