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WorksheetsMediator of Inflammation
Total questions: 15
Worksheet time: 12mins
Which of the following is a property of mediators of inflammation?
Produced locally by cells at the site of inflammation
Derived from active precursors
Long-lived
Cannot stimulate other mediators.
Fill in the blank: _______ are newly synthesized mediators from all leukocytes, platelets, and EC.
Prostaglandins
Serotonin
Lysosomal enzymes
Histamine
Which mediator is sourced from mast cells, basophils, and platelets?
Serotonin
Nitric oxide
Histamine
Cytokines
Fill in the blank: _______ are mediators that cause the dilation of blood vessels and increase the permeability of capillaries.
A) Kinins
B) Prostaglandins
C) Cytokines
D) Chemokines
Fill in the blank: _______ are mediators that are involved in the regulation of immune responses and inflammation.
Cytokines
Histamine
Prostaglandins
Chemokines
Which of the following mediators is involved in the process of vasodilation and increased vascular permeability?
Kinins
Leukotrienes
Complement
Cytokines
Histamine is associated with which of the following actions?
Endothelial activation
Muscle relaxation
Neuronal inhibition
Bone growth
Leukotrienes are produced in leukocytes and _______ cells.
mast
red blood
nerve
muscle
Leukotrienes are involved in _______ and smooth muscle reactions.
leukocyte recruitment
protein synthesis
DNA replication
cell division
Which cytokine is primarily sourced from macrophages and other cells and is involved in systemic effects?
IL-6
IL-1
TNF
IL-17
Kinins are derived from plasma proteins by the action of specific proteases called ______.
Kallikreins
Kininogens
Enzymes
Hormones
Fill in the blank: The activation of plasminogen to plasmin is part of the _______ system.
Kinin
Clotting
Fibrinolytic
Complement
Which action is associated with leukotrienes C4, D4, E4?
A) Vasodilation
B) Vasoconstriction
C) Increased vascular permeability
D) Chemotaxis, leukocyte adhesion.
What is the effect of Prostaglandin E2 (PGE2) on blood vessels?
Causes vasoconstriction
Causes vasodilation
Inhibits platelet aggregation
Promotes inflammation
Which mediator is known for its role in chemotaxis of leukocytes?
Histamine
Leukotrienes
Cytokines
Prostaglandins
