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WorksheetsUrinary System 1 for Medical Students
Total questions: 29
Worksheet time: 27mins
What is the function of erythropoietin?
Increases RBC production
Increases Hb production
Increases iron metabolism
Increases bone marrow proliferation
A 40-year-old man with smoking 20 years has low serum oxygen saturation due to chronic lung disease. What is the addaptation of his hematologic system?
Increased Hb level
Decreased Hb level
Increased hepatic iron storage
Decreased hepatic iron storage
What is the function of angiotensin II?
Vasocontriction
Aldosterone stimulation
Vascular smooth muscle cell proliferation
All of them
A 40-year-old man with CKD stage 2 (eGFR 70 mL/min) starts ACE inhibitor. After a week, his eGFR drops to 65 mL/min. His clinical is stable and he refused of taking other drugs/supplement or having accident. What is the most appropriate management.
Observe
Stop ACE inhibitor
Increase dose of ACE inhibitor
Add a diuretic
Measure cystatin to confirm the eGFR level
Which is true regarding parathyroid hormone vs FGF23 function in renal phosphate reabsorption?
They counteracts each other on the same transporter.
They effects inversely on the different transporters
They have similar effects on the same transporter.
They have similar effects but affect on different transporters.
Parathyroid hormone regulates vitamin D by ?
Stimulation
Inhibition
Work synergistically
No effect
What is the receptors of FGF23?
FGF21 receptor
FGF 23 receptors
Klotho
FGF23-Klotho receptor
FGF23 regulates vitamin D by ?
Stimulation
Inhibition
Work synergistically
No effect
What is the common source of energy used by renal cortex?
What is the Renal rubular transporter responsible for renal glucose reabsorption?
GLUT1
GLUT2
SGLT1
SGLT2
Which of the following hormones has the LEAST effect on renal glucose etabolism?
Insulin
Glucagon
Catecholamine
Cortisol
What is the alteration of renal tubular response to glucose in diabetes?
Decreased renal glucose threshold
Increased renal glucose threshold
Decreased renal gluconeogenesis
Increased renal gluconeogenesis
Patients with massive proteinuria has high fat content in renal tubular cells causing renal lipotoxicity. Where is the most common source of this fat?
Blood
Urine
Endogenous (intracellular synthesis)
Exogenous (trasnported from liver)
What is the main function of megalin?
facilitate all kinds of protein reabsorption
Facilitate only albumin reabsorption
Facilitate albumin and lipid reabsorption
Facilitate only renal-derived protein reabsorption
In healthy adult, serum carnitine is derived from?
Liver
Kidney
Food
All are correct
Where is/are the target tissues of lactate produced by renal medulla?
Liver
Lung
Kidney
Liver and kidney
What is/are the products of citrate synthesis by renal tubular cells?
CO2
Acetyl CoA
Oxaloacetate
All of them
What is/are the functions of neprilysin?
Degrades ANP
Degrades BNP
Degrades angiotensin II
All of them
Which of the following glomerular tissues does not involves in preservation of serum albumin?
Bowman's capsule
Glomerular endothelial cell
Glomerular basement membrane
Podocyte process
Which of the following is/are considered as the main charge barrier for urinary protein leakage?
Glomerular endothelial cell
Glomerular basement membrane
Podocyte process
All of them
Which of the following protein(s) is/are responsible for presevation of serum albumin leakage in slit diaphragm?
Glycocalyx
Collagen type IV
Laminin
NEPH-1
What is the most abundant renal protein in urine?
Albumin
Tamm-horsfall
Urokinase
Globulin
Which of the following condition increased urinary albumin excretion rate?
Decreased renal blood flow
Increased renal blood flow
Glomerular hypertension
Non-functioning glomeruli
24-hour urine urea (BUN) can be used to estimate daily intake of?
Which of the followling conditions is commonly found in patients with Type 2 DM for 15 years with well controlled blood sugar?
Hematuria
Leukuria
Proteinuria
Cast
In a patient with metabolic acidosis, renal ammonia production will be ......
Which of the following conditions presents with WBC casts and positive nitrite in urine?
Pyelonephritis
Cystitis
Drug-induced nephritis
Urolithiasis
Which of the following patients most likely has the highest RAAS activity?
A boy with high-grade fever and seizure
A man with congestive heart failure
A marathon runner who did not drink for -hours running
A woman with heavy menstruation
A girl with bilateral renal artery stenosis
Which hormones are produced by kidneys?
