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First and Second Line Defense Immune

Total questions: 10

Worksheet time: 5mins

Name
Class
Date
1.

Name the process a cell such as a neutrophil or a macrophage uses to engulf its prey

a)

halitosis

b)

chemotaxis

c)

botulism

d)

phagocytosis

2.

The second line of defence includes:

a)

Inflammation and fever

b)

Targeting specific pathogens

c)

Production of antibodies

d)

Chemical barriers like acids, enzymes, and other secretions

3.

A sign that shows your second line of defence has been triggered:

a)

redness

b)

swelling

c)

inflammation

d)

all of the above

4.

What is the correct order of enzyme activation cascade in the blood clotting process?

a)

Fibrin, fibrinogen, thrombin, prothrombin

b)

Prothrombin, thrombin, fibrin, fibrinogen

c)

Thrombin, prothrombin, fibrin, fibrinogen

d)

Prothrombin, thrombin, fibrinogen, fibrin

5.

The second line of defence helps to:

a)

prevent pathogens from entering body

b)

fight all types pathogens once they have entered the body

c)

fight off specific pathogens, remember pathogens that have previously invaded

6.

What is the correct order of the events in phagocytosis?

a)

discharge, fusion with lysosome, phagosome forms, detection, digestion, ingestion

b)

detection, ingestion, digestion, phagosome forms, fusion with lysosome, discharge

c)

ingestion, detection, digestion, fusion with lysosome, phagosome forms, discharge

d)

detection, ingestion, phagosome forms, fusion with lysosome, digestion, discharge

7.

Neutrophils are a type of white blood cell involved in the second line of defense. Neutrophils:

a)

envelope pathogens that have entered the body

b)

promote blood flow

c)

secrete antibodies

d)

secrete antigens

8.

During the inflammation process the mast cells release _________, which causes vasodilation.

a)

Histamine

b)

Prostaglandins

c)

PAMPS

d)

Fibrin

9.

What is the function of fibrin in blood clotting?

a)

Catalyses the conversion of the soluble plasma protein fibrinogen

b)

It forms an insoluble mesh of fibres which traps blood cells at the site of damage.

c)

Promotes the release of clotting factors

d)

Recognised by Pattern recognition receptors (PRRs) in a variety of body cells

10.

What effect does histamine produce in the inflammation process:

a)

Decreases blood supply to the injury site

b)

Causes vasoconstriction

c)

Increases capillary permeability

d)

Increases heart rate