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AP Biology Gene Regulation

Total questions: 15

Worksheet time: 15mins

Name
Class
Date
1.

Why might a point mutation in DNA make a difference in the level of proteinʹs activity?

a)

It might substitute an amino acid in the active site.

b)

It might exchange one stop codon for another stop codon.

2.

What does the operon model attempt to explain?

a)

the coordinated control of gene expression in bacteria

b)

the mechanism of viral attachment to a host cell

3.

When this is taken up by the cell, it binds to the repressor so that the repressor no longer binds to the operator:

a)

inducer

b)

repressor

4.

Transcription of the structural genes in an inducible operon

a)

occurs continuously in the cell.

b)

starts when the pathwayʹs substrate is present.

5.

Muscle cells and nerve cells in one species of animal owe their differences in structure to

a)

having different genes.

b)

having different genes expressed.

6.

If you were to observe the activity of methylated DNA, you would expect it to

a)

be unwinding in preparation for protein synthesis.

b)

have turned off or slowed down the process of transcription.

7.

Which enzyme was used to produce the molecule in the Figure?

a)

ligase

b)

a restriction enzyme

8.

Which of the following describe the structure of mature RNA? (more than 1 answer applies)

a)

Contains Uracil

b)

Contains introns and exons

c)

Has a poly-A tail and 5' cap

d)

Single stranded

e)

Circular strand

9.

Which of the following would be transcribed from the following DNA sequence? 3' ATC GAA TTA CGA 5'

a)

5' UAG CUU AAU GCU 3'

b)

5' AUC GAA UUA CGA 3'

c)

3' UCG UAA UUC UAG 5'

d)

3' TAG CTT AAT GCT 5'

e)

5' TAG CTT AAT GCT 3'

10.

Which enzyme catalyzes the elongation of a DNA strand in the 5ʹ → 3ʹ direction?

a)

primase

b)

DNA ligase

c)

DNA Polymerase

d)

helicase

11.

In the lac operon model, what is the role of the repressor protein?

a)

A) It binds to the operator to prevent transcription.

b)

B) It enhances the binding of RNA polymerase to the promoter.

c)

C) It acts as a co-repressor to activate gene expression.

d)

D) It degrades mRNA to stop protein synthesis.

12.

Which of the following is a mechanism of gene regulation in eukaryotes?

a)

A) RNA splicing

b)

B) Operon model

c)

C) Attenuation

d)

D) Feedback inhibition

13.

What is the function of an enhancer in gene regulation?

a)

A) It increases the rate of transcription when bound by specific proteins.

b)

B) It silences gene expression by binding to the promoter.

c)

C) It acts as a repressor to inhibit transcription.

d)

D) It degrades mRNA to prevent translation.

14.

How does DNA methylation affect gene expression?

a)

A) It typically suppresses gene expression by adding methyl groups to DNA.

b)

B) It enhances gene expression by loosening chromatin structure.

c)

C) It has no effect on gene expression.

d)

D) It increases the rate of transcription by binding to enhancers.

15.

In an experiment, a scientist observes that a certain gene is not expressed in the presence of glucose. What type of gene regulation is likely involved?

a)

A) Catabolite repression

b)

B) Positive feedback

c)

C) Negative feedback

d)

D) Inducible operon