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WorksheetsApoptosis
Total questions: 15
Worksheet time: 15mins
What is apoptosis?
Programmed cell death
Uncontrolled cell growth
Cell division
Cell differentiation
Which of the following is a key feature of apoptosis?
Cell swelling
Cell shrinkage
Inflammation
Necrosis
Which organelle is primarily involved in the intrinsic pathway of apoptosis?
Nucleus
Mitochondria
Endoplasmic reticulum
Golgi apparatus
Which protein family is crucial for the execution of apoptosis?
Caspases
Kinases
Phosphatases
Ligases
What role do Bcl-2 proteins play in apoptosis?
Inhibit apoptosis
Promote apoptosis
Repair DNA
Facilitate cell division
Which of the following is a characteristic of apoptotic cells?
Membrane blebbing
Cell fusion
Cell proliferation
Cell migration
How does apoptosis differ from necrosis?
Apoptosis is a controlled process, necrosis is not
Apoptosis causes inflammation, necrosis does not
Apoptosis results in cell swelling, necrosis in cell shrinkage
Apoptosis is a form of cell growth, necrosis is cell death
Which of the following is an example of apoptosis in development?
Formation of fingers and toes
Growth of hair
Increase in muscle mass
Expansion of lung capacity
What is the role of cytochrome c in apoptosis?
Activates caspases
Inhibits DNA replication
Promotes cell division
Blocks protein synthesis
Which assay is commonly used to detect apoptosis?
TUNEL assay
ELISA
Western blot
PCR
What is the significance of phosphatidylserine exposure on the cell surface during apoptosis?
Signals phagocytes to engulf the cell
Prevents cell division
Initiates DNA replication
Causes cell fusion
Which of the following diseases is associated with dysregulation of apoptosis?
Cancer
Diabetes
Hypertension
Asthma
What is the role of p53 in apoptosis?
Induces apoptosis in response to DNA damage
Prevents apoptosis
Facilitates cell division
Inhibits protein synthesis
How is apoptosis beneficial in the immune system?
Eliminates harmful or unnecessary cells
Promotes inflammation
Increases antibody production
Enhances pathogen entry
Which of the following is a morphological change observed in apoptosis?
Chromatin condensation
Cell fusion
Cell elongation
Cytoplasmic expansion
