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CBNS 120 MT 1 Review

Total questions: 15

Worksheet time: 11mins

Name
Class
Date
1.
1. Em deviates at low [K+]o primarily due to
a)
driving force for K+
b)
Na+/K+ ATPase
c)
Na+ conductance
d)
Ca2+ conductance
2.
2. How do invertebrates typically increase conduction velocity?
a)
myelination
b)
glial cells
c)
increase axon radius
d)
saltatory conduction
3.
3. Driving force is described as:
a)
Vm + Ex
b)
Vm - Ex
c)
(Vm)(Ex)
d)
Ex - Vm
4.
4. In a voltage clamp experiment:
a)
membrane voltage is kept constant
b)
membrane voltage is manipulated
c)
membrane current is kept constant
d)
action potentials are recorded
5.
5. Which of the following is true regarding a voltage-gated K+ channel?
a)
contains 4 voltage sensors
b)
contains 6 transmembrane segments per subunit
c)
blocked TEA
d)
blocked by TTX
6.
6. The Goldman equation takes into account the effects of
a)
voltage-gated Ca2+ channels
b)
Na+/K+ ATPase
c)
leak K+ channels
d)
Cl- movement
7.
7. To increase the conduction velocity in an unmyelinated axon, you can increase
a)
time constant
b)
internal resistance
c)
length constant
d)
axon radius
8.
8. The nicotinic Acetylcholine receptor contains:
a)
a voltage sensor
b)
2 acetylcholine binding sites
c)
6 subunits
d)
an inactivation particle
9.
9. Which of the following is true regarding NCX?
a)
sodium goes against its concentration gradient
b)
net positive charge flows out
c)
sodium enters the cell while calcium exits the cell
d)
requires ATP
10.
10. if [Na+]o was reduced:
a)
ENa also reduces
b)
Action potential amplitude increases
c)
Action potential amplitude decreases
11.
11. The slow AHP is:
a)
eliminated by introducing Cd2+
b)
reduced when lowering [Ca2+]o
c)
enhanced by repetitive action potential activity
d)
caused by the persistent Na+ channel
12.
12. The Hodgkin-Huxley equation describes:
a)
4 activation particles for voltage gated K+ channels
b)
4 activation particles for voltage gated Na+ channels
c)
1 inactivation particle for voltage gated Na+ channels
d)
1 inactivation particle for voltage gated K+ channels
13.
13. If you were to decrease the leak gNa in the squid:
a)
Em depolarizes
b)
Em hyperpolarizes
c)
Em doesn't change
14.
14. The IFM motif:
a)
has a binding site inside the channel
b)
inactivates voltage-gated Na+ channel
c)
is intracellular
d)
is extracellular
15.
15. The S4 motif:
a)
causes gating current
b)
causes capacitive current
c)
moves towards the extracellular side to activate the channel