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Chapter 12 KUV

Total questions: 21

Worksheet time: 14mins

Name
Class
Date
1.

Recombinant DNA technology is used:

a)

For production of herbicide-resistant plant.

b)

To make a particular protein.

c)

To clone a specific piece of DNA

d)

All of the above.

2.

Which of the following is correct about host cell?

a)

Plasmid is an example of host cell.

b)

Unable to receive DNA molecule through transformation.

c)

An organism that prevents cloning vectors from multiplying.

d)

An organism that is used to receive recombinant DNA for cloning purposes.

3.

What is the purpose of amplification?

a)

To screen for recombinant bacteria.

b)

To join the rDNA with the host cell.

c)

To produce multiple copies of the desired gene.

d)

To prevent the bacteria from reproducing.

4.

Which of these pairs is incorrectly matched?

a)

DNA ligase – mapping human chromosomes

b)

Target DNA – gene of interest

c)

Taq polymerase – PCR

d)

Plasmid as a vector – isolated from bacteria

5.

Which of these might be a biotechnology product?

a)

Vaccine.

b)

Modified enzyme.

c)

Protein hormone.

d)

All of the above.

6.

Plants are more readily manipulated by genetic engineering than are animals because:

a)

Plant genes do not contain introns.

b)

A somatic plant cell can often give rise to a complete plant.

c)

Genes can be inserted into plant cells by microinjection.

d)

Plant cells have larger nuclei.

7.

The following are steps involved in gene cloning procedures. Rearrange them into the correct sequence:

I. Transformation and amplification.

II. Screen for bacteria that contain recombinant

DNA.

III. Insert DNA fragment into the cut bacterial

plasmid.

IV. Cleave the plasmid and human DNA with the same restriction enzyme.

V. Isolate the bacterial plasmid and human DNA.

a)

A. I, II, III, IV, V

b)

B. V, IV, III, I, II

c)

C. V, IV, III, II, I

d)

D. IV, V, III, I, II

8.

In genetic engineering, DNA ligase is used as:

a)

a probe

b)

a sealing enzyme

c)

a restriction enzyme

d)

a mutagen

9.

Which one of the following statements about Restriction Endonuclease is true

a)

all restriction endonucleases cut DNA at specific sites

b)

all restriction endonucleases cut DNA at random sites

c)

all restriction endonucleases join DNA segments at specific sites

d)

all restriction endonucleases join DNA at random sites

10.
What is the purpose of PCR?
a)
To produce millions of copies of DNA.
b)
To produce millions of copies of a specific region of DNA
c)
To add nucleotides to a DNA sequence
d)
To watch polymerase work.
11.
At what temperature does the Denature step of PCR occur?
a)
94-96° C
b)
50-65° C
c)
72° C
d)
Any temperature
12.
Why does PCR require a specific type of polymerase?
a)
Taq polymerase can withstand the range of temperatures in PCR without denaturing.
b)
Taq polymerase is the most inexpensive type of polymerase.
c)
Taq polymerase is the most common type of polymerase.
d)
A specific type of polymerase is unnecessary.
13.

The first step in PCR is

a)

Primer annealing

b)

Denaturation

c)

Primer extension

d)

None of these

14.
What happens during the Anneal step of PCR?
a)
Primers are created.
b)
The primers attach to the target DNA region.
c)
Primers copy the new DNA strand.
d)
Primers sequence DNA
15.

What is the denaturation step?

a)

mutating RNA polymerase

b)

Cooling DNA to allow primers to form

c)

separating DNA helix in a cold environment

d)

separating DNA helix with using heat

16.

CRISPR system evolved in bacteria and archaea in their defense against....

a)

Coronaviruses

b)

Chemical reagents

c)

Bacteriophage

d)

Other bacteria

17.

Which suspect should be charged with the crime?

a)

Suspect 1

b)

Suspect 2

c)

Suspect 3

d)

None of these suspects

18.

Which sequence of DNA bases would pair with this partial strand

ATG TGA CAG

a)

ATG TGA CAG

b)

TAC ACT GTC

c)

GTA AGT GAC

d)

CAT TCA CTG

19.

This process of DNA fingerprinting separates the DNA fragments through a gel using an electrical current.

a)

DNA Extraction

b)

Polymerase Chain Reaction

c)

Gel Electrophoresis

d)

DNA Replication

20.

Which suspect is linked to the crime scene by this DNA analysis?

a)

Suspect A

b)

Suspect C

c)

Suspect D

d)

Suspect B

21.

In Paternity Tests, to know Whether a person wants to prove they are or are not the father, it is necessary:

a)

DNA from the baby solely

b)

DNA from both the potential father and the potential mother

c)

DNA from both the potential father and the baby