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BCBIO23-LAB CA

Total questions: 20

Worksheet time: 10mins

Name
Class
Date
1.

The cells synthesize RNA, growth factors and other molecules required for cell division.

a)

Lag Phase

b)

Log Phase

c)

Stationary Phase

d)

Death Phase

2.

This phase is marked by the doubling of the bacterial cells.

a)

Lag Phase

b)

Log Phase

c)

Stationary Phase

d)

Death Phase

3.

The cell population remains constant at this stage. Plotting this phase on the graph gives a smooth horizontal linear line.

a)

Lag Phase

b)

Log Phase

c)

Stationary Phase

d)

Death Phase

4.

This is the last phase of the bacterial growth.

a)

Lag Phase

b)

Log Phase

c)

Stationary Phase

d)

Death Phase

5.

What is the typical wavelength used to measure bacterial growth in a spectrophotometer?

a)

200 nm

b)

260 nm

c)

600 nm

d)

800 nm

6.

The Kirby-Bauer method is used to assess antibiotic sensitivity. What is the key indicator of antibiotic effectiveness?

a)

Zone of inhibition

b)

Increase in colony count

c)

Change in color of the agar plate

d)

pH variation

7.

Why is it important to use a control plate when testing antibiotic sensitivity?

a)

To ensure uniform bacterial growth

b)

To check for contamination

c)

To compare growth in the absence of antibiotics

d)

All of the above

8.

What is the role of ethidium bromide in agarose gel electrophoresis?

a)

To break down DNA

b)

To stain DNA for visualization under UV light

c)

To increase the migration speed of DNA

d)

To degrade proteins

9.

Why is loading dye added to DNA samples before running gel electrophoresis?

a)

To increase the density of the sample

b)

To visualize DNA bands

c)

To enhance DNA degradation

d)

To cut DNA into smaller fragments

10.

If two bands appear for the same plasmid DNA sample after gel electrophoresis, what does it indicate?

a)

Presence of RNA contamination

b)

Degradation of DNA

c)

Different conformations of plasmid DNA (supercoiled and relaxed)

d)

Presence of genomic DNA contamination

11.

What factor influences the migration speed of DNA in an agarose gel?

a)

Size of DNA fragments

b)

Strength of electric field

c)

Concentration of agarose

d)

All of the above

12.

If no plaques are observed after incubation in a bacteriophage isolation experiment, what could be the reason?

a)

No bacteriophages were present in the sample

b)

The bacterial strain used was resistant to infection

c)

The incubation conditions were not optimal

d)

All of the above

13.

Which method is commonly used to isolate bacteriophages from environmental samples?

a)

Agar dilution method

b)

Soft agar overlay method

c)

Gram staining

d)

PCR analysis

14.

Bacteriophages are viruses that specifically infect:

a)

Fungi

b)

Bacteria

c)

Plants

d)

Animals

15.

The zone of inhibition in antibiotic-producing bacteria is due to:

a)

Nutrient consumption

b)

Antibiotic diffusion

c)

Mutation in bacterial genes

d)

Increased oxygen concentration

16.

What is the function of chloroform in bacteriophage isolation?

a)

It enhances phage adsorption

b)

It lyses bacterial cells to release phages

c)

It stains phages for visualization

d)

It acts as a pH buffer

17.

What do plaques represent in a bacteriophage isolation experiment?

a)

Bacterial contamination

b)

Areas where phages have lysed bacteria

c)

Dead phages

d)

Bacterial colonies

18.

Which of the following conditions can affect plaque size in a bacteriophage experiment?

a)

All of the above

b)

Host bacterial strain

c)

Agar concentration

d)

Incubation time

19.

A zone of inhibition for penicillin against Staphylococcus aureus is measured to be 22 mm. If the required zone for susceptibility is ≥18 mm, is the bacteria susceptible or resistant?

a)

Susceptible

b)

Resistant

c)

Intermediate

d)

Cannot determine

20.

You inoculate 10 mL of bacterial culture into 90 mL of fresh medium. What is the dilution factor?

a)

1:5

b)

1:10

c)

1:50

d)

1:100