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PreTEST CAD

Total questions: 5

Worksheet time: 3mins

Name
Class
Date
1.

  Cold agglutinin disease is most commonly seen among

a)

Men

b)

Women

2.

It typically occurs in response to an underlying condition. These can include infections, autoimmune diseases, or lymphoproliferative disorders.

a)

Idiopathic cold agglutinin disease

b)

Primary Cold agglutinin Disease

c)

Cold agglutinin syndrome

d)

Benign cold agglutinin

3.

What is the key pathogenic mechanism in Cold Agglutinin Disease (CAD)?

a)

Complement fixation initiated by IgM

b)

Autoantibody-mediated destruction by IgG

c)

T-cell–mediated cytotoxicity

d)

Phagocytosis by dendritic cells

4.

Which type of antibody is primarily involved in Cold Agglutinin Disease?

a)

IgM

b)

IgG

c)

IgA

d)

IgE

5.

Which statement is FALSE regarding the risk assessment based on thermal amplitude and plasma titer?

a)

Low-thermal amplitude (20°C) may not be at risk of agglutination

b)

Low titer (<1:32) may not be at risk of agglutination

c)

Hemolysis is rarely seen if the titer is below 1:1000

d)

Antibody titer up to 1:40 is clinically significant