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POST TEST CAD

Total questions: 5

Worksheet time: 3mins

Name
Class
Date
1.

This mechanism of drug-mediated immune injury to RBCs occurs as drugs in this group exhibit only weak direct binding to RBC membranes; thus, cellular injury is primarily mediated by complement activation at the cell surface, and a relatively small dose is needed to trigger the destruction of RBCs.  

a)

Hapten-drug adsorption

b)

Ternary complex

c)

Autoantibody binding

d)

All of the above

2.

Based on the case report and series presented, which drug used for CML had the highest incidence of causing cold agglutinin?

a)

Interferon

b)

Imatinib

c)

Bosulfan

d)

Bosutinib

3.

Patients with benign CA (but without evidence of CHAD) who can safely undergo cardiac surgery with normothermia and warm cardioplegia at 37°C do not require additional testing.

a)

True

b)

False

4.

Cold agglutinins are autoantibodies, most commonly of the IgM class, that target which specific antigens on the surface of red blood cells (RBCs)?

a)

I antigen

b)

Duffy

c)

Kid

d)

Kell

5.

Direct Anti-globulin Test is essentially useful among the following except:

a)

Autoimmune hemolytic anemia (AIHA)


b)

Hemolytic disease of the newborn

c)

Hemolytic transfusion reactions

d)

Pre-transfusion testing (antibody screening and cross-matching)