WorksheetsER: ID
Total questions: 58
Worksheet time: 29mins
A 22-year-old woman presents with cervical motion tenderness and yellow vaginal discharge. A PCR test confirms Chlamydia trachomatis. She is not pregnant and has no drug allergies. What is the appropriate treatment?
Azithromycin 1 g PO x1
Doxycycline 100 mg PO bid x 7 days
Metronidazole 2 g PO x1
Ceftriaxone 500 mg IM x1
A 25-year-old male presents with urethral discharge and dysuria. Gram stain shows gram-negative diplococci. He weighs 160 kg. What is the correct treatment?
Ceftriaxone 500 mg IM x1
Ceftriaxone 1 g IM x1
Doxycycline 100 mg PO bid x 7 days
Azithromycin 1 g PO x1
A 30-year-old woman presents with a frothy green vaginal discharge and vaginal itching. Wet prep reveals motile protozoa. What is the best treatment?
Doxycycline 100 mg PO bid x 7 days
Metronidazole 2 g PO x1
Ceftriaxone 250 mg IM x1
Acyclovir 400 mg PO tid x 7 days
A 27-year-old male presents with painful grouped vesicles on an erythematous base on the penis. He also has fever and lymphadenopathy. What is the appropriate initial treatment?
Ceftriaxone 500 mg IM x1
Doxycycline 100 mg PO bid x 7 days
Acyclovir 400 mg PO tid for 7–10 days
Azithromycin 1 g PO x1
A 32-year-old man presents with a painful genital ulcer and tender inguinal lymphadenopathy. What is the best empiric treatment?
Azithromycin 1 g PO x1
Acyclovir 400 mg PO tid
Penicillin G 2.4 million units IM
Doxycycline 100 mg PO bid x 21 days
A 28-year-old male presents with tender inguinal lymphadenopathy and reports a painless ulcer 2 weeks ago that has resolved. What is the most appropriate treatment?
Ceftriaxone 500 mg IM x1
Acyclovir 400 mg PO tid x 7 days
Doxycycline 100 mg PO bid x 21 days
Azithromycin 1 g PO x1
A 19-year-old woman presents with lower abdominal pain, abnormal vaginal discharge, and cervical motion tenderness. She is sexually active with inconsistent condom use. There is no fever. Which organism is most likely responsible?
Neisseria gonorrhoeae
Trichomonas vaginalis
Chlamydia trachomatis
Treponema pallidum
A 21-year-old male presents with dysuria and copious purulent urethral discharge. He denies any rash or lesions. Gram stain reveals gram-negative diplococci. Which pathogen is most likely?
Haemophilus ducreyi
Chlamydia trachomatis
Neisseria gonorrhoeae
Ureaplasma urealyticum
A 26-year-old female presents with vaginal itching and frothy greenish-yellow discharge. A wet mount reveals motile flagellated protozoa. What is the most likely diagnosis?
Bacterial vaginosis
Candidiasis
Trichomoniasis
Gonorrhea
A 29-year-old man presents with painful grouped vesicles on the shaft of his penis and tender inguinal lymphadenopathy. He reports flu-like symptoms and burning with urination.
Syphilis
HSV
Chancroid
LGV
A 35-year-old male presents with a painful genital ulcer and unilateral, tender inguinal lymphadenopathy. The lesion has irregular borders and a purulent base. What is the most likely diagnosis?
HSV
LGV
Chancroid
Syphilis
A 30-year-old man presents with tender inguinal lymphadenopathy ("buboes") and reports a painless ulcer on the penis that appeared two weeks ago and resolved spontaneously. He recently traveled to the Caribbean. What is the most likely diagnosis?
Syphilis
LGV
Chancroid
Gonorrhea
A 58-year-old man is brought in with altered mental status, fever, and hypotension. He meets 2 SIRS criteria, has a suspected infection, and a lactate of 5.2 mmol/L. What is the next best step?
Start norepinephrine immediately
Obtain blood cultures, then start broad-spectrum antibiotics
Delay antibiotics until ICU admission
Give dexamethasone before fluids
Which fluid resuscitation strategy is recommended within the first 3 hours for a patient with hypotension and suspected septic shock?
10 mL/kg NS
30 mL/kg crystalloid
1 L of D5NS over 4 hours
Albumin 5% bolus
In early sepsis, an initial lactate level of 4.5 mmol/L suggests:
Adequate perfusion
Need for blood transfusion
Significant hypoperfusion
Hepatic dysfunction only
Which pressor is considered first-line for septic shock unresponsive to fluid resuscitation?
Dobutamine
Epinephrine
Norepinephrine (Levophed)
Dopamine
A septic patient receives a 30 mL/kg bolus but remains hypotensive. MAP is 62 mm Hg. What's the next step?
Add corticosteroids
Start vasopressors
Repeat fluid bolus only
Observe for 6 hours
What is the minimum MAP goal when titrating vasopressors in septic shock?
60 mm Hg
65 mm Hg
75 mm Hg
90 mm Hg
Which of the following must be repeated within 6 hours if initially elevated?
INR
Hematocrit
Lactate
Platelet count
Why are antibiotics given before completing all labs in septic shock?
To reduce cost
Because cultures are unnecessary
Early antibiotics improve mortality
Imaging must confirm infection first
What's the most important first step in managing sepsis?
Airway control
Early pressors
Identifying source and initiating antibiotics
Foley catheter placement
In septic shock, which of the following indicates organ dysfunction?
MAP = 70
Platelets = 180,000
Lactate = 3.0 mmol/L
WBC = 12,500
Which is part of the 3-hour bundle in sepsis management?
Central line placement
Vasopressors
Reassess fluid status
Blood cultures before antibiotics
Which is included in the 6-hour bundle?
Measure lactate
Start norepinephrine
Insert Foley catheter
Start empiric antifungals
A patient with septic shock requires pressors. Where should they be administered?
Peripheral IV
Intraosseous access
Central venous line
Subcutaneous injection
Which of the following findings does NOT define sepsis-related organ dysfunction?
Bilirubin 1.2
Platelets 90,000
INR 1.7
Urine output <0.5 mL/kg/hr for 2 hours
A patient has sepsis with respiratory failure requiring intubation. What does this indicate?
Mild infection
No end-organ damage
Organ dysfunction
Transient hypoxia
A 21-year-old woman presents with lower abdominal pain and mucopurulent cervical discharge. PCR confirms Chlamydia trachomatis. What is the treatment of choice?
Metronidazole 2 g PO x1
Ceftriaxone 500 mg IM x1
Doxycycline 100 mg PO bid x 7 days
Acyclovir 400 mg PO tid
A 25-year-old male presents with copious purulent urethral discharge and dysuria. Gram stain shows gram-negative diplococci. What is the correct treatment?
Azithromycin 1 g PO x1
Ceftriaxone 500 mg IM x1
Doxycycline 100 mg PO bid x 7 days
Metronidazole 500 mg PO bid x 7 days
A woman presents to the ED with vaginal itching, foul-smelling yellow-green frothy discharge, and erythema. Motile protozoa are seen on wet mount. What is the recommended treatment?
Doxycycline 100 mg PO bid x 7 days
Azithromycin 1 g PO x1
Metronidazole 2 g PO x1
Ceftriaxone 1 g IM x1
A patient presents with painful genital ulcers, fever, and tender inguinal lymphadenopathy. PCR confirms HSV-2. What is the best initial treatment?
Penicillin G 2.4 million units IM x1
Acyclovir 400 mg PO tid for 7–10 days
Azithromycin 1 g PO x1
Doxycycline 100 mg PO bid x 21 days
A 34-year-old man presents with a painful genital ulcer and purulent base, along with unilateral tender lymphadenopathy. Which treatment is appropriate?
A. Acyclovir 400 mg PO tid x 7 days
B. Azithromycin 1 g PO x1
C. Ceftriaxone 250 mg IM x1
D. Both B and C are acceptable
A male patient presents with tender inguinal buboes and reports a painless ulcer on the penis 2 weeks prior. Which infection and treatment are correct?
HSV; acyclovir 400 mg PO tid
LGV; doxycycline 100 mg PO bid x 21 days
Chancroid; azithromycin 1 g PO x1
Syphilis; penicillin G 2.4 million units IM
A 23-year-old woman with vaginal discharge and dysuria tests positive for both gonorrhea and chlamydia. What is the appropriate ED treatment?
Azithromycin 1 g PO x1
Ceftriaxone 500 mg IM + doxycycline 100 mg PO bid x 7 days
Metronidazole 500 mg PO bid x 7 days
Acyclovir 400 mg PO tid
A 29-year-old man presents with painless ulcer on the penis. He is not circumcised and reports unprotected sex. Which of the following is most likely?
HSV-2
Chancroid
Syphilis
Trichomonas
A 31-year-old woman presents with burning urination and a positive wet mount for Trichomonas vaginalis. Which advice should be emphasized at discharge?
Begin iron supplements
Avoid dairy for 48 hours
Avoid alcohol for 48–72 hours
Take with high-fat meals
A patient with active genital HSV lesions is pregnant and goes into labor. What is the appropriate course of action?
Allow vaginal delivery
Administer IV penicillin
Start suppressive acyclovir therapy
Proceed with C-section
Dengue fever is most commonly transmitted by which of the following?
Anopheles mosquito
Contaminated seafood
Aedes mosquito
Tick bite
A traveler returns from the Caribbean with fever, retro-orbital pain, and facial flushing. What is the most likely diagnosis?
Malaria
Dengue fever
Typhoid fever
RMSF
What is the recommended treatment for dengue fever?
IV quinidine
Azithromycin
Supportive care
Oseltamivir
Malaria is caused by which genus of protozoa?
Giardia
Trypanosoma
Plasmodium
Cryptosporidium
Which of the following symptoms is most characteristic of malaria?
Painless genital ulcer
Cyclic fevers and splenomegaly
Facial flushing and retro-orbital pain
Non-bloody diarrhea
Which medication is first-line for severe malaria?
Chloroquine
IV artesunate
Acyclovir
Metronidazole
RMSF (Rocky Mountain Spotted Fever) is caused by which of the following organisms?
Rickettsia rickettsii
Plasmodium falciparum
Campylobacter jejuni
Vibrio cholerae
Which rash is most characteristic of RMSF (Rocky Mountain Spotted Fever)?
Vesicular rash on trunk
Rash starting on palms and soles
Maculopapular rash starting on wrists and ankles
Petechial rash on face
What is the treatment of choice for RMSF (Rocky Mountain Spotted Fever), even in pregnancy?
Azithromycin
Penicillin G
Doxycycline
Ceftriaxone
Which of the following organisms is a common cause of traveler’s diarrhea?
HSV-2
Plasmodium vivax
E. coli
Rickettsia typhi
A 24-year-old traveler presents with fever, cramping, and bloody diarrhea. Which diagnosis is most likely?
Norovirus
Traveler’s diarrhea
Hepatitis B
RMSF
What is the recommended treatment for febrile traveler’s diarrhea if antimicrobial therapy is needed?
A. Acyclovir
B. Vancomycin
C. Ciprofloxacin
D. Nystatin
Ciguatera poisoning is associated with consumption of which type of fish?
Shellfish like clams
Raw freshwater fish
Reef fish like barracuda and snapper
Spoiled tuna
Which neurologic symptom is considered pathognomonic for ciguatera?
Retro-orbital pain
Cold allodynia (hot-cold reversal)
Ascending weakness
Facial paralysis
What is an adjunctive treatment sometimes used for neurologic symptoms of ciguatera poisoning?
Doxycycline
IV mannitol
Vancomycin
Prednisone
Scombroid poisoning is caused by which of the following mechanisms?
Dinoflagellate neurotoxins
Histamine buildup from spoiled fish
Bacterial enterotoxins
Shellfish proteins
A patient develops flushing, palpitations, and oral burning within 20 minutes of eating tuna. What's the likely diagnosis?
Ciguatera
Shellfish allergy
Scombroid poisoning
RMSF
Which medication is first-line for scombroid poisoning?
A. Epinephrine
B. Antihistamines (H1 + H2 blockers)
C. Doxycycline
D. Metronidazole
PSP (paralytic shellfish poisoning) is caused by ingestion of shellfish contaminated with:
Staph enterotoxin
Histamine
Saxitoxins
Botulinum toxin
Which of the following is most characteristic of PSP (paralytic shellfish poisoning)?
Ascending paralysis with areflexia
Paresthesias of the mouth, ataxia, and respiratory depression
Jaundice and RUQ pain
Vesicular rash and myalgia
What is the priority treatment for a patient with PSP (paralytic shellfish poisoning) and respiratory compromise?
IV ciprofloxacin
Naloxone
Antitoxin
Airway protection and supportive care
