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Immunohepatology and transfusion medicine

Total questions: 25

Worksheet time: 14mins

Name
Class
Date
1.

Which is not a mandatory test in screening of blood donation

a)

Hepatitis C antibody

b)

Hepatitis B

c)

Malaria

d)

VDRL

e)

Typhoid

2.

One unit of PRBC must be completely transferred within

a)

30 minutes

b)

4 hours

c)

6 hours

d)

8 hours

3.

A young male met with an accident and is brought to the ER with shock. Blood group of the patient is not known. This patient needs immediate blood transfusion, so which will be the most appropriate blood group to be given?

a)

O +ve

b)

AB +ve

c)

O -ve

d)

AB -ve

4.

Patient with DIC has Hb - 7g/dL and requires blood transfusion. One RBC unit is removed from the storage and should be transfused

a)

Within 1 hr of removal from cold storage

b)

Within 30 minutes of removal from cold storage

c)

After warming to 37°C

d)

Within 2hrs or when the unit has done to room temperature

5.

Truth about the development of anti A and anti B antibodies after birth is

a)

Develop in response to development of corresponding B on A antigens on RBCs

b)

Are inherited from the mother

c)

Develop in response to exposure to blood products

d)

Produced in response to bacteria, viruses and other substances that are inhaler or ingested

6.

Age limit for apheresis donation

a)

18-60 years

b)

15-45 years

c)

20-60 years

d)

18-65 years

7.

Condition Donor referral criteria

A)Dengue 1)Permanent Deferral

B)Minor Surgery 2)Permanent Deferral

C)MI 3)6 months

D)Previous Blood transfusion 4)12 months E)Etretinate 5)3 months

a)

A-2,B-3,C-5,D-1,E-4

b)

A-3,B-5,C-1,D-4,E-2

c)

A-2,B-3,C-5,D-4,E-1

d)

A-3,B-2,C-5,D-1,E-4

8.

Which statement is not true about Direct Coomb's test

a)

It detects antibody bound to RBC membrane

b)

It may detect complements attached to the RBC membrane

c)

It detects antibody circulating in the plasma

d)

AHG Reagent is used

9.

Which is true in Bombay phenotype?

a)

Autosomal dominant

b)

Contains A, B and H antigens

c)

Secretor

d)

Non secretor

10.

Interval between whole blood donation for males is _________ months and females is ______ months.

a)

5,6

b)

8,10

c)

3,4

d)

1,2

11.

Match the following

Anticoagulant Shelf life

1) CPD a)42 days

2) CPDA-1 b)21 days 3)ACD c)35 days

4)SAGM d)21 days

a)

1-b,2-c,3-d,4-a

b)

1-a,2-c,3-d,4-b

c)

1-a,2-b,3-c,4-d

d)

1-d,2-a,3-b,4-c

12.

True regarding platelet transfusion is

a)

Transfusion should begin as soon as platelets are received from the blood bank

b)

Stored at 20-24°C

c)

Kept on agitator

d)

All of the above

e)

None of the above

13.

Which antibodies will detect in immediate spin cross match and AHG crossmatch?

a)

IgM and IgG

b)

IgG and IgM

c)

IgM and IgE

d)

IgG and IgA

14.

Which of the following statements best describes the recent advancements in artificial blood research in Japan, as reported in scientific literature and transfusion medicine texts?

a)

Japan has developed a universal artificial blood containing synthetic hemoglobin and platelets that requires ABO matching.

b)

Japanese researchers developed a freeze-dried artificial blood capable of carrying oxygen and promoting clotting, tested successfully in animals

c)

Artificial blood research in Japan is focused exclusively on perfluorocarbon-based oxygen carriers

d)

Japan prohibits the use of artificial blood in clinical trials due to ethical concerns

15.

Which of the following is Rh antigen

a)

ABO

b)

K

c)

D

d)

MNS

16.

Bombay phenotype differentiated from 'O' Blood group using

a)

Anti A1 lectin

b)

Anti D

c)

Anti H lectin

d)

None of the above

17.

Which of the following will lead to intravascular hemolysis?

a)

Group 'O' RBC to group A recipient

b)

Group 'O' RBC to group AB recipient

c)

Rh+ve RBC to Rh negative Recipient

d)

Group 'A' RBC to group O recipient

18.

For whole blood donation in females Hb should be more than (a)   g/dL

19.

Which component is stored at 20-24°C

a)

PRBCs

b)

FFP

c)

Platelets

d)

Cryoprecipitate

20.

False about polycythemia vera

a)

JAK 2 mutation

b)

Therapeutic phlebotomy is a treatment

c)

Blood collected from polycythemic person can be used for transfusion

d)

Not more than 2 units removed during 24 hr period

21.

Platelet is stored for (a)   days

22.

Packed RBCs are prepared by

a)

Titration

b)

Centrifugation

c)

Precipitation

d)

Sedimentation

23.

1 single donor platelet equals to ____ RDP (Random Donor Platelets)

a)

2

b)

6

c)

3

d)

9

24.

False about single donor platelet component is

a)

Reduces multiple donor exposure

b)

Reduced blood products

c)

Increase risk of cytomegalovirus infection

d)

Better quality product

25.

Cryoprecipitate contains

a)

Factor 7

b)

Factor 9

c)

Factor 12

d)

Factor 1