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Erythropoiesis and Coagulation Quiz

Total questions: 20

Worksheet time: 10mins

Name
Class
Date
1.

Which is the earliest recognizable cell in erythropoiesis?

a)

Reticulocyte

b)

Proerythroblast

c)

Normoblast

d)

Megakaryocyte

2.

Erythropoiesis predominantly occurs in adults at?

a)

Liver

b)

Femur

c)

Red bone marrow of flat bones

d)

Yolk sac

3.

Which hormone is the major stimulator of erythropoiesis?

a)

Insulin

b)

Erythropoietin

c)

Testosterone

d)

Thyroxine

4.

Erythropoietin is primarily secreted by?

a)

Liver

b)

Red bone marrow

c)

Kidneys

d)

Spleen

5.

During fetal life, erythropoiesis in the liver is most active during?

a)

First trimester

b)

Second trimester

c)

Third trimester

d)

Birth

6.

Final stage of erythrocyte maturation before becoming a mature RBC is?

a)

Normoblast

b)

Reticulocyte

c)

Proerythroblast

d)

Myelocyte

7.

Which of the following is a nutrient essential for DNA synthesis in erythropoiesis?

a)

Iron

b)

Vitamin B12

c)

Vitamin C

d)

Copper

8.

Which of the following is needed for hemoglobin synthesis?

a)

Zinc

b)

Iron

c)

Vitamin D

d)

Calcium

9.

Intrinsic pathway is initiated by?

a)

Tissue damage

b)

Exposure to collagen

c)

Thromboplastin

d)

Calcium

10.

Extrinsic pathway is initiated by?

a)

Platelet aggregation

b)

Endothelial injury

c)

Tissue thromboplastin

d)

Calcium

11.

Common pathway of coagulation begins with activation of?

a)

Factor X

b)

Factor VII

c)

Prothrombin

d)

Thrombin

12.

Which ion is essential for all steps in blood clotting?

a)

Sodium

b)

Potassium

c)

Calcium

d)

Magnesium

13.

Fibrin is formed from?

a)

Fibrinogen by thrombin

b)

Prothrombin by calcium

c)

Factor X by thrombin

d)

Fibrinogen by Factor XII

14.

Vitamin K is essential for synthesis of which clotting factor?

a)

Factor I

b)

Factor VII

c)

Factor IV

d)

Factor XII

15.

Which is a natural anticoagulant?

a)

Thrombin

b)

Heparin

c)

Factor V

d)

Vitamin K

16.

What is the function of thrombin?

a)

Converts fibrin to fibrinogen

b)

Converts prothrombin to thrombin

c)

Converts fibrinogen to fibrin

d)

Activates platelets

17.

Which test is used to assess intrinsic pathway?

a)

Prothrombin Time (PT)

b)

Bleeding time

c)

Partial Thromboplastin Time (PTT)

d)

Platelet count

18.

Deficiency of factor VIII leads to?

a)

Hemophilia A

b)

Hemophilia B

c)

Von Willebrand disease

d)

Scurvy

19.

The extrinsic pathway is assessed clinically by?

a)

PT

b)

PTT

c)

Bleeding time

d)

Clotting time

20.

Which clotting factor is also called Hageman factor?

a)

Factor IX

b)

Factor XI

c)

Factor XII

d)

Factor X