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WorksheetsGenetic Code and Mutations Quiz
Total questions: 20
Worksheet time: 10mins
Genetic code is described as ‘degenerate’ because
Each codon codes for multiple amino acids
More than one codon can code for a single amino acid
Each amino acid is coded by only one codon
All codons code for start signals
Which amino acid has only one codon?
Valine
Leucine
Methionine
Serine
The start codon for translation in eukaryotes is
UGA
AUG
UAA
UAG
Wobble hypothesis explains
Initiation of translation
Termination of translation
Third base flexibility in tRNA pairing
Protein folding
According to Wobble hypothesis, the ‘wobble’ occurs at
1st position of codon
2nd position of codon
3rd position of codon
4th position of codon
A point mutation involves
Insertion of a base
Deletion of a base
Substitution of one base
Inversion of bases
Which mutation leads to complete shift in reading frame?
Silent mutation
Missense mutation
Frameshift mutation
Point mutation
A silent mutation results in
Stop codon
Change in amino acid
No change in amino acid
Frameshift
Which of the following is an example of a missense mutation?
Sickle cell anemia
Phenylketonuria
Thalassemia
Alkaptonuria
Protein folding is aided by which class of proteins?
Ligases
Chaperones
Proteases
Kinases
Which structure of protein is most affected by folding?
Primary
Secondary
Tertiary
Quaternary
Protein targeting ensures proteins reach
Only nucleus
Only cytoplasm
Their correct cellular location
Only mitochondria
Which organelle is involved in post-translational protein modification?
Ribosome
Nucleus
Golgi apparatus
Lysosome
In LAC operon, the structural genes include
Lac Z, Lac Y, Lac A
Lac I, Lac P, Lac O
Lac Z, Lac R, Lac I
Lac P, Lac Y, Lac R
Lac Z, Lac Y, Lac A
The repressor of the lac operon is coded by which gene?
Lac A
Lac Z
Lac I
Lac Y
Which molecule inactivates the repressor of the lac operon?
Lactose
Allolactose
Glucose
Galactose
LAC operon is induced in presence of
Glucose only
Lactose only
Both glucose and lactose
Lactose and absence of glucose
Which of the following acts as a negative regulator in lac operon?
RNA polymerase
Promoter
Operator
Repressor
CAP-cAMP complex enhances transcription in LAC operon by binding to
Operator
Promoter
Repressor gene
Structural gene
Frameshift mutations are commonly caused by
Base substitution
Base addition or deletion
Chromosome translocation
Nonsense codons
