Wayground logo

Free Printable Worksheets

Font size

S
M
L
XL
Worksheets

Prep for Final Semi 2

Total questions: 54

Worksheet time: 18mins

Name
Class
Date
1.

In abetalipoproteinemia, which of the following lipoproteins is NOT absent in plasma?

a)

HDL

b)

LDL

c)

Chylomicrons

d)

VLDL

e)

IDL

2.

What structural characteristic distinguishes trans fats from cis fats?

a)

Number of carbon atoms

b)

Length of the hydrocarbon chain

c)

Position of H atoms relative to double bonds

d)

Saturation level

3.

Which enzyme catalyzes the first step of beta-oxidation?

a)

Acetyl-CoA synthetase

b)

Acyl-CoA dehydrogenase

c)

Enoyl-CoA hydratase

d)

3-Ketoacyl-CoA thiolase

e)

HMG-CoA synthase

4.

Hypertriglyceridemia is most commonly associated with which of the following?

a)

Deficient production of chylomicrons

b)

Lipoprotein lipase deficiency

c)

Elevated HDL levels

d)

Increased beta-oxidation

e)

High dietary cholesterol

5.

Which of the following is the main substrate for ketogenesis?

a)

Fatty acids

b)

Glucose

c)

Pyruvate

d)

Amino acids

e)

Lactate

6.

Chylomicrons are primarily responsible for transporting:

a)

Endogenous triglycerides

b)

Dietary triglycerides

c)

Cholesterol esters

d)

Free fatty acids

e)

Phospholipids

7.

In ketoacidosis, elevated ketone bodies result in which of the following acid-base imbalances?

a)

Metabolic alkalosis

b)

Respiratory acidosis

c)

Metabolic acidosis

d)

Respiratory alkalosis

e)

Mixed acidosis

8.

The main apolipoprotein of HDL is:

a)

ApoA-I

b)

ApoB-100

c)

ApoC-II

d)

ApoE

e)

ApoB-48

9.

Fat malabsorption can result in deficiency of which of the following vitamins?

a)

Vitamin C

b)

Vitamin B6

c)

Vitamin A

d)

Vitamin B12

e)

Folic acid

10.

Which is the primary site of ketone body production?

a)

Brain

b)

Adipose tissue

c)

Liver

d)

Skeletal muscle

e)

Pancreas

11.

Familial hypercholesterolemia results from a mutation in which gene?

a)

APOE

b)

LDLR

c)

CETP

d)

HMG-CoA reductase

e)

ABCA1

12.

Which enzyme is inhibited by NSAIDs?

a)

COX-1 and COX-2

b)

Lipoxygenase

c)

Phospholipase A2

d)

HMG-CoA reductase

e)

AMP-dependent kinase

13.

Which lipoprotein is most directly responsible for reverse cholesterol transport?

a)

Chylomicrons

b)

LDL

c)

HDL

d)

VLDL

e)

IDL

14.

Lipoxins are anti-inflammatory mediators derived from:

a)

Prostaglandins

b)

Leukotrienes

c)

Palmitic acid

d)

Cholesterol

e)

Thromboxanes

15.

The primary function of COX-1 is:

a)

Pro-inflammatory cytokine production

b)

Maintenance of gastric mucosa

c)

Leukotriene synthesis

d)

Beta-oxidation of fatty acids

e)

Regulation of lipid absorption

16.

The overproduction of leukotrienes is most commonly associated with which condition?

a)

Hypertension

b)

Asthma

c)

Osteoarthritis

d)

Diabetes mellitus

e)

Hyperlipidemia

17.

What is the major energy source for muscle during fasting?

a)

Ketone bodies

b)

Fatty acids

c)

Glycogen

d)

Amino acids

e)

Glucose

18.

The Cori cycle connects which two tissues?

a)

Liver and muscle

b)

Adipose and brain

c)

Liver and brain

d)

Kidney and muscle

e)

Adipose and liver

19.

Which of the following metabolic pathways is suppressed during starvation?

a)

Gluconeogenesis

b)

Lipolysis

c)

Cholesterol synthesis

d)

Beta-oxidation

e)

Ketogenesis

20.

Which of the following minerals is a cofactor for insulin action?

a)

Copper

b)

Chromium

c)

Zinc

d)

Iron

e)

Iodine

21.

Which desaturase enzyme is absent in humans, making certain fatty acids essential?

a)

Δ4 desaturase

b)

Δ5 desaturase

c)

Δ6 desaturase

d)

Δ9 desaturase

e)

Δ12 desaturase

22.

Which structural feature of trans fats contributes to their harmful effects on cardiovascular health?

a)

Increased chain length

b)

Higher oxidative stability

c)

Linear configuration of double bonds

d)

Increased water solubility

e)

Greater susceptibility to lipase hydrolysis

23.

Hyperthyroidism is most commonly caused by:

a)

Hashimoto's thyroiditis

b)

Graves' disease

c)

Iodine deficiency

d)

Pituitary adenoma

e)

Cushing's syndrome

24.

In non-alcoholic fatty liver disease (NAFLD), which of the following contributes most significantly to hepatic fat accumulation?

a)

Increased beta-oxidation

b)

Enhanced de novo lipogenesis

c)

Elevated VLDL secretion

d)

Impaired ketogenesis

e)

Decreased dietary fat intake

25.

In Zellweger syndrome, very long-chain fatty acids (VLCFAs) accumulate due to:

a)

Defective peroxisomal beta-oxidation

b)

Increased mitochondrial beta-oxidation

c)

Enhanced ketogenesis

d)

Overexpression of HMG-CoA synthase

e)

Decreased lipolysis

26.

The activation of fatty acids for beta-oxidation requires:

a)

Conversion to fatty acyl-CoA by carnitine acyltransferase

b)

Hydrolysis of ATP to AMP

c)

Transport into the mitochondria via CPT-II

d)

Hydrolysis of ADP to ATP

e)

Oxidation to acetyl-CoA in the cytosol

27.

Thyroid hormones belong to which type of hormones?

a)

Steroid

b)

Protein

c)

Amine

d)

Glycoprotein

e)

Glycolipid

28.

A deficiency of LDL receptors causes which compensatory change in cholesterol metabolism?

a)

Increased HDL synthesis

b)

Enhanced HMG-CoA reductase activity

c)

Elevated CETP activity

d)

Decreased hepatic VLDL secretion

e)

Upregulation of chylomicron production

29.

Which of the following is the most specific marker of chylomicron metabolism?

a)

ApoE

b)

ApoC-II

c)

ApoB-48

d)

ApoA-I

e)

ApoB-100

30.

In lipoprotein lipase deficiency, which of the following lipid abnormalities is observed?

a)

Isolated hypercholesterolemia

b)

Elevated chylomicrons and VLDL

c)

Increased HDL

d)

Reduced LDL

e)

Normal triglycerides

31.

In primary hypothyroidism, which hormonal pattern is most commonly observed?

a)

Elevated TSH and low T3/T4

b)

Elevated TSH and elevated T3/T4

c)

Low TSH and elevated T3/T4

d)

Low TSH and low T3/T4

e)

Normal TSH with low T3/T4

32.

Congenital adrenal hyperplasia due to 21-hydroxylase deficiency is associated with:

a)

Hyperkalemia

b)

Hypertension

c)

Hypernatremia

d)

Increased cortisol production

e)

Decreased androgens

33.

Which enzyme requires thiamine pyrophosphate (TPP) as a cofactor?

a)

Pyruvate kinase

b)

Pyruvate dehydrogenase

c)

Lactate dehydrogenase

d)

Hexokinase

e)

Isocitrate dehydrogenase

34.

Which of the following biochemical processes is directly affected in scurvy?

a)

Glycogenolysis

b)

Proline hydroxylation

c)

Gluconeogenesis

d)

Fatty acid oxidation

e)

Cholesterol biosynthesis

35.

Pellagra, characterized by dermatitis, diarrhea, and dementia, results from a deficiency in:

a)

Riboflavin

b)

Niacin

c)

Pyridoxine

d)

Biotin

e)

Thiamine

36.

Hereditary orotic aciduria is caused by a deficiency in:

a)

PRPP synthetase

b)

UMP synthase

c)

Carbamoyl phosphate synthetase I

d)

Ornithine transcarbamylase

e)

Xanthine oxidase

37.

Which enzyme primarily converts ethanol to acetaldehyde in the liver?

a)

Acetaldehyde dehydrogenase

b)

Alcohol dehydrogenase

c)

Cytochrome P450 2E1

d)

Aldehyde oxidase

e)

Catalase

38.

The accumulation of NADH during ethanol metabolism inhibits which metabolic pathway?

a)

Glycolysis

b)

Gluconeogenesis

c)

Fatty acid synthesis

d)

Glycogenolysis

e)

Cholesterol synthesis

39.

Which hormone directly increases the activity of lipoprotein lipase in adipose tissue?

a)

Cortisol

b)

Glucagon

c)

Insulin

d)

Epinephrine

e)

Growth hormone

40.

Carnitine palmitoyltransferase I (CPT-I) is inhibited by which molecule?

a)

Acetyl-CoA

b)

Malonyl-CoA

c)

Citrate

d)

NADH

e)

FADH2

41.

The conversion of HMG-CoA to acetoacetate occurs in which cellular compartment?

a)

Cytosol

b)

Mitochondria

c)

Endoplasmic reticulum

d)

Peroxisomes

e)

Lysosomes

42.

Deficiency of peroxisomal beta-oxidation primarily leads to accumulation of:

a)

Short-chain fatty acids

b)

Medium-chain fatty acids

c)

Very long-chain fatty acids

d)

Ketone bodies

e)

Branched-chain amino acids

43.

Which step in the reverse cholesterol transport pathway involves the enzyme lecithin-cholesterol acyltransferase (LCAT)?

a)

Esterification of cholesterol on HDL

b)

Cholesterol efflux from macrophages

c)

Uptake of HDL by the liver

d)

Cholesterol transfer to VLDL

e)

Synthesis of ApoA-I

44.

Which eicosanoid acts as a potent platelet aggregator and vasoconstrictor?

a)

Prostaglandin E2

b)

Thromboxane A2

c)

Leukotriene B4

d)

Lipoxin A4

e)

Prostaglandin I2

45.

Which vitamin deficiency leads to impaired gamma-carboxylation of clotting factors?

a)

Cholecalciferol

b)

Phylloquinone

c)

Retinol

d)

Ascorbate

e)

Pyridoxine

46.

Excessive consumption of raw egg whites leads to which vitamin deficiency?

a)

Thiamine

b)

Riboflavin

c)

Biotin

d)

Niacin

e)

Pyridoxine

47.

Which hormone's receptor is intracellular and directly binds to DNA?

a)

Insulin

b)

Glucagon

c)

Cortisol

d)

Growth hormone

e)

Epinephrine

48.

Thyroid hormones are synthesized and stored in which form within the thyroid gland?

a)

Free hormones

b)

Bound to globulin in the bloodstream

c)

As thyroglobulin

d)

As iodide ions

e)

As triiodothyronine (T3)

49.

In starvation, muscle protein breakdown is stimulated primarily by:

a)

Glucagon

b)

Cortisol

c)

Insulin

d)

Growth hormone

50.

What is the major fuel for the brain during the first few days of fasting?

a)

Fatty acids

b)

Glucose

c)

Ketone bodies

d)

Amino acids

e)

Glycerol

51.

Which mineral deficiency leads to goiter?

a)

Iron

b)

Zinc

c)

Iodine

d)

Selenium

e)

Copper

52.

Gallstone formation is associated with:

a)

Increased bile acid synthesis

b)

Reduced cholesterol solubility in bile

c)

Elevated lecithin concentration

d)

Increased bile flow

e)

Decreased biliary bilirubin

53.

Which drug inhibits xanthine oxidase to treat gout?

a)

Probenecid

b)

Allopurinol

c)

Colchicine

d)

Methotrexate

e)

Indomethacin

54.

The synthesis of purines begins with which molecule?

a)

Aspartate

b)

Glycine

c)

Ribose-5-phosphate

d)

Glutamine

e)

Carbamoyl phosphate

Similar Resources on Wayground

Modes of reproduction

51 questions

Modes of reproduction

quiz

Worksheet

•

10th Grade - University

Nematology (SPEC 4)

50 questions

Nematology (SPEC 4)

quiz

Worksheet

•

University

Chapters 34/36

50 questions

Chapters 34/36

quiz

Worksheet

•

9th Grade - University

PHC I MIDTERM ARPILLEDA

50 questions

PHC I MIDTERM ARPILLEDA

quiz

Worksheet

•

University

BIO122 CHAPTER 2_Part 1

50 questions

BIO122 CHAPTER 2_Part 1

quiz

Worksheet

•

11th Grade - University

Released SOL

50 questions

Released SOL

quiz

Worksheet

•

9th Grade - University

MA ch10 Infection Control

52 questions

MA ch10 Infection Control

quiz

Worksheet

•

University

BIO201 KELLAR EXAM 3 REVIEW

50 questions

BIO201 KELLAR EXAM 3 REVIEW

quiz

Worksheet

•

University