CBL: Case-Based Learning Scenario

Case: A 36 year old male is brought to the emergency department with confusion, nausea, and blurred vision. His friends report he had consumed homemade liquor the night before. His breath has a fruity odor, and fundus examination shows signs of optic nerve damage. Lab tests show high anion gap metabolic acidosis.

1. What is the most likely diagnosis?

CBL: Case-Based Learning Scenario

Case: A 45 year old female presents to the clinic with severe abdominal pain, vomiting, and confusion. She has a history of binge drinking and reports consuming a large quantity of alcohol the previous night. Physical examination reveals jaundice and asterixis. Lab tests indicate elevated liver enzymes and a high anion gap.

1. What is the most likely diagnosis?

Which of the following is a lipotropic factor important for preventing fatty liver?

alcohol-induced hypoglycemia, which gluconeogenic intermediate is reduced due to high NADH/NAD+ ratio?

Which of the following metabolic changes does NOT occur in chronic alcohol use?

What is the calorific value (kcal/gm) of ethanol?

What is the primary metabolic pathway for ethanol oxidation in the liver?

In the context of alcohol metabolism, what effect does a high NADH/NAD+ ratio have on the liver?

In the context of alcohol metabolism, what is the consequence of increased NADH levels?